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Every Step Counts: New Study Shows Even Light Exercise Slashes Stroke Risk!

Written by Andrew Le, MD

UpdatedApril 17, 2024

Leisure-time physical activity (LTPA) is widely recognized for its beneficial effects on vascular health. A new study has systematically reviewed and analyzed how different intensities of LTPA—from very light to intense—impact the prevention of strokes. This article provides a synopsis of the study's background, methodology, and findings, as well as insights into how these results could influence public health recommendations and individual behaviors related to stroke prevention.

Background

Strokes are a leading cause of disability and death, casting a heavy burden on individuals, societies, and healthcare systems globally. It’s well accepted that engaging in leisure-time physical activity can guard against a variety of vascular diseases, including strokes. However, it was not clear if this protective effect was limited only to moderate or intense levels of physical activity, or whether lighter forms of physical activity could also provide benefits for stroke prevention.

Methodology

To shed light on this question, researchers conducted a comprehensive search for studies offering insights into the relationship between various predefined levels of leisure-time physical activity and the risk of any type of stroke in healthy populations. Their search spanned articles indexed in PubMed and Scopus up until April 22, 2023, which they then filtered down through a specific selection process.

Random-effect modeling was employed for meta-analyses, a statistical approach that considers the variations between different studies. They also performed meta-regression analyses to adjust for factors like age and sex that might influence the outcomes.

Results

After an extensive screening of 3,064 articles, the team selected 15 studies involving 16 cohorts—with a collective 752,050 subjects—for their meta-analyses. The average follow-up period for these studies was roughly 10.5 years.

Within these studies, varying levels of leisure-time physical activity were categorized, ranging from none to intense. The studies commonly identified three to five distinct levels of physical activity—including none, below target, ideal, insufficient, low, moderate, and intense.

The analysis revealed several key findings:

  • In studies with three levels of physical activity, engaging in physical activity below the recommended target still reduced stroke risk by 18%, while ideal activity levels reduced risk by 29% compared with no physical activity at all.
  • Studies that identified four levels of physical activity showed a reduced risk of 27% for moderate physical activity compared to no activity.
  • Lastly, in the more nuanced breakdown of five levels, moderate levels of activity led to a similar 29% reduction in stroke risk compared to inactivity.

Importantly, the researchers determined that the benefits of leisure-time physical activity were consistent regardless of the participant's age or sex.

Conclusions

The overarching conclusion of the study is that all levels of leisure-time physical activity are beneficial for stroke prevention. This includes even those levels that might be considered low or insufficient relative to existing public health guidelines, which typically recommend a minimum of 150 minutes of moderate activity or 75 minutes of vigorous activity per week to prevent cardiovascular diseases, including strokes.

The evidence from this study suggests that health campaigns and individual exercise plans should encourage people to engage in physical activity no matter how light, as even small amounts can contribute to reducing the risk of stroke. This finding could have significant implications for public health strategies, especially in terms of designing inclusive recommendations that can cater to a wide spectrum of abilities and lifestyles.

By demonstrating that even low levels of physical activity can be stroke-preventative, this study offers encouragement for individuals who may not reach standard activity goals but can still achieve health benefits from whatever amount of physical activity they can manage. It challenges the "all or nothing" mindset sometimes associated with exercise regimens and supports a more nuanced understanding of the health benefits of physical activity.

References

De Santis F, Romoli M, Foschi M, Sciancalepore FD, D'Anna L, Barba L, Abu-Rumeileh S, Sacco S, Ornello R. Risk of stroke with different levels of leisure-time physical activity: a systematic review and meta-analysis of prospective cohort studies. J Neurol Neurosurg Psychiatry. 2024 Mar 5:jnnp-2023-332457. doi: 10.1136/jnnp-2023-332457. Epub ahead of print. PMID: 38443158.