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Top 12 Best Mushroom Supplements

UpdatedDecember 7, 2023

Medicinal mushrooms have been used in many cultures around the world in traditional medicine and, now, modern treatments. Still, they remain a delectable delicacy with health benefits to the human body. As a value add, edible varieties are ingredients in mushroom supplementation, popular for their health perks. So what are the best mushroom supplements? Stick around for a well-curated list of my favorite supplements in the market.

Top 3 Best Mushroom Supplements

  1. Quality of Life Premium Kinoko Platinum AHCC Herbal Supplement
  2. Nootrum Mushrooms
  3. NutriFlair Mushroom Supplement

Quality of Life Premium Kinoko Platinum AHCC Herbal Supplement

Editor's Choice

Elevate your well-being with Premium Kinoko Platinum AHCC. This powerhouse supplement enhances immunity and overall wellness, backed by a proven track record and premium ingredients. While the price and dosage may be considerations, the potential benefits make it a worthwhile investment in your health.

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Quality of Life Premium Kinoko Platinum AHCC Herbal Supplement is a remarkable choice for individuals who are committed to enhancing their overall well-being through the use of high-quality dietary supplements.


  • With extensive research backing its claims, this supplement is a reliable choice for those seeking results.
  • Regular use can fortify your body's natural defenses, helping you stay healthy and resilient.
  • It backed by clinical trials and studies, providing evidence of its efficacy.
  • It is crafted with the utmost care, ensuring that only the highest quality ingredients are used.


  • Costly
  • Requires consistent use.

Incorporating Premium Kinoko Platinum AHCC into your daily regimen can yield a substantial improvement in your quality of life. Whether you're looking to boost your immune system or simply enhance your overall wellness, this supplement's track record of effectiveness and the high standard of its ingredients make it a compelling choice. Just keep in mind that its price and dosage complexity may be factors to consider, but the potential benefits make it a worthwhile investment in your health and well-being.

Nootrum Mushrooms

The Most Comprehensive Mushrooms

Unlock the full power of mushrooms with Nootrum Mushrooms! Packed with 10-20 times more b-glucans, lectins, and phenolics than standard extracts, each capsule equals 3 grams of Reishi, Shiitake, Lion’s Mane, and Cordyceps. Experience ultimate nootropic, immune, and energy benefits. Plus, enjoy a risk-free trial with their money-back guarantee. Elevate your well-being today!

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Nootrum Mushrooms uses high yield extracts to fit an awful lot into a small package. Their mushroom extracts contain 10-20 times the amount of b-glucans, lectins and phenolics than standard extracts meaning that one of their capsules is the equivalent to 3grams of Reishi, Shiitake, Lion’s Mane and Cordyceps each! That means that you get the best of mushrooms nootropic effects as well as the immune and energy boost.

They also offer a money back guarantee, so if you’re not satisfied with Nootrum, then you’ve lost nothing.


  • Premium Quality Ingredients: Nootrum Mushrooms boast a meticulously curated blend of top-tier mushroom extracts, elevating its nutritional profile.
  • Versatility: This supplement transcends dietary boundaries, accommodating various preferences as it is vegan, gluten-free, and adheres to kosher standards.
  • Comprehensive Health Support: Nootrum Mushrooms go beyond the ordinary, providing holistic support for cognitive function, immune health, and overall vitality.
  • Abundant Supply: Each container generously holds a sufficient quantity, offering a prolonged period of reaping the benefits—90 capsules to sustain my well-being journey.
  • Certified Excellence: Backed by certifications attesting to its authenticity, Nootrum Mushrooms are a testament to quality, holding certifications for being USDA-certified organic and non-GMO.
  • Conscious Sourcing: Rooted in ethical practices, the brand prioritizes sustainable sourcing, ensuring that the journey from harvest to supplement aligns with environmentally responsible standards.


  • Patience Required: Similar to any profound wellness regimen, it may take time to fully experience the noticeable effects of Nootrum Mushrooms.

NutriFlair Mushroom Supplement

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Featuring 10 types of mushrooms, the kick starter pick, NutriFlair Mushroom Supplement, contains beneficial compounds that give a boost to the immune system, focus, and memory. Additionally, I like that this comprehensive mushroom supplement contains mushroom species that we are familiar with, including reishi and maitake mushrooms. Furthermore, this supplement also supports optimal cholesterol and balances hormones.

I also commend this brand for making their product 100% vegan and natural. There aren't any additives or artificial supplements, which makes it an excellent choice if you prefer all-natural ingredients. Furthermore, I prefer how there is no aftertaste after taking the supplements, and you don't have to worry about a pungent smell.

Lastly, I also noticed that the tablets are very large compared to normal tablets. Therefore, if you have a problem taking tablets, it might be a good idea to break them in half before taking them. It is easier if you space the three tablets throughout the day instead of taking them at once.


  • No side effects
  • All-natural
  • Improves energy levels
  • Unflavored
  • No aftertaste


  • Large tablets

Om Mushroom Superfood Master Blend Mushroom Powder Supplement

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For full-spectrum immune system health, this is the mushroom supplement for you. This is a powder supplement form that contains 34 servings. Additionally, it is infused with organic reishi mushroom, with 9 other mushroom species that have a ton of beneficial compounds. Furthermore, I like that this supplement also has 3 organic botanical adaptogens for that energy boost you need in the morning.

Apart from cognitive perks, this supplement also helps with anxiety and fatigue and gives a general sense of well-being. We tried taking the powder with water and coffee, but the taste is more bearable with a smoothie, tea, and a sweetener like honey. It's not bitter; it just has an earthy flavor, which might be overwhelming to some people.

Additionally, as one of the top-rated mushroom supplements, it blends in food or other drinks fairly well. I noticed a difference in taking this supplement within a few days. It is a great starting point if you have been looking for a mushroom supplement.


  • Easily dissolves
  • Value for money
  • Vegan friendly
  • Supports overall health
  • Great for gut health


  • Might give you a slight stomach ache

FreshCap, Ultimate Mushroom Complex Capsule

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This mushroom supplement contains up to 29% of beta-glucans, which are the active beneficial compounds in mushroom supplements. This cocktail of mushrooms has reishi, turkey tail, lion's mane, cordyceps, chaga, and maitake mushrooms.

This supplement is easy to take since it doesn't have any aftertaste or flavor, and the capsule form is easy to swallow.I experienced positive results within a few daysof taking this supplement, especially with digestion and intestinal cramps. Furthermore, reishi mushroom extracts are great for regulating your blood pressure.

I also enjoyed howthere is a visible boost in energy and focus when you incorporate the supplement into your breakfast. If you lack sleep, this will come in handy for those restless nights. It is also perfect if you wake up feeling groggy in the mornings.


  • Easy to swallow
  • Fast acting
  • Energizing
  • Affordable
  • High-quality


  • You will get heartburn in the first few weeks

Genius Mushroom - A Blend of Lions Mane, Cordyceps, and Reishi Mushrooms

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Everything from this brand is vegan, and the best part is you can’t taste the real mushroom flavor of the supplements. Additionally, thanks to the elevated concentrations of mushroomextracts from different species, you can lead a healthier life thanks to these capsules. Furthermore, I observed that itis one of those mushroom supplements that encourage natural energy production for a healthy lifestyle.

Whether you’re a pro athlete, stay-at-home parent, retiree, or anything in between, this mushroom company has something for everyone. Your boost in cognitive function will be noticeable within a few weeks of incorporating this supplement into your daily regimen. Of course, I noticed and increase in focus when it came to everyday work.

Furthermore, it helped me adapt to stress the same way an adaptogen would. Additionally, it boosts my energy levels, but not how a stimulant like coffee would. It also increases cognitive function, making me more awake and alert during the day.


  • Easy to digest
  • No side effects
  • High-quality
  • No noticeable aftertaste


  • The pills are large and hard to swallow

Organic Lions Mane Mushroom Capsules

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If you want to improve cognitive health, this is the mushroom supplement for you. As we age, we wake up feeling groggy in the morning, and this leads to a sluggish day, spacing out, and feeling general tiredness. This is one of the best mushroom supplements if you need a gradual effect since you will experience the full health benefits, including all its energizing properties for better mornings.

Of course, when it comes to medicinal mushroom supplements, I like to recommend patience since it takes a while for the effects to kick in. Still, the gradual but sure benefits are hard to dispute. Of course, taking this mushroom supplement daily keeps you sharp and focused on everyday activities. Furthermore, you won't experience burnout as easily as before.

I also recommend this mushroom supplement for anyone who needs extra energy, a general sense of well-being, and to boost energy. They are also perfect for older people and help with healthy brain function and immune support.


  • Easy to swallow
  • No flavor
  • No aftertaste
  • 2-month supply


  • You might get a minor tummy ache

Aceworkz Mushroom Supplement - Infused With Lions Mane, Reishi, and Cordyceps Mushrooms

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Made with organically grown mushrooms, this supplement is filled with antioxidants and immune defense properties to optimize a strong and adaptive immune system. We all know the feeling of waking up groggy and dazed. This mushroom blend gives you the mental clarity to go about your day.

It's a great supplement for gut health, and it will help your sleeping patterns if you suffer from irregular or lack of sleep. Plus, this mixture of beneficial mushrooms also improves mood and calms anxiety. Of course, the effects are gradual and not immediate, unlike pharmaceutical medication.

The pills are larger than usual, but they still go down easily. However, Inoticed a lingering aftertaste that's gag-worthy. Apart from that, this is still one of the best mushroom supplements for general health and well-being.


  • No side effects
  • Easy to digest
  • Leads to increased productivity
  • Potent


  • Lingering aftertaste
  • Large pills

VEGATOT 10 in 1 High Strength Mushroom Supplement

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Made with high-quality mushroom supplements, this supplement is concentrated with 10 mushroom species, including lion's mane, cordyceps, turkey tail, Agaricus, enoki, and shiitake mushrooms.

With these functional mushrooms in your supplement, you will notice your brain fog and forgetfulness lifting within a few weeks of use. Of course, I should also mention how the pills regulate high blood pressure. However, you need to remember to take two pills a day to see the effects. The correct dosage will help you to focus and get rid of fatigue and burnout.

Pure mushroom supplements, like Vegatot, are made using a unique process that concentrates the bioactive compounds found in mushrooms. This results in a more potent and effective supplement compared to other options on the market.Hence, I got a boost in energy levels due to the resulting potency.


  • Potent
  • High-quality ingredients
  • Vegan friendly
  • Easy to swallow
  • 90 day supply


  • Acne-prone people might get breakouts

Satoomi 10 in-1 Mushroom Complex

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A dose of this mushroom supplement daily is perfect for optimizing your mental and physical well-being.Additionally, this sugar-free supplement makes my mornings energized and rejuvenated. Furthermore, there is a lot of effort, including third-party lab testing, that has gone into creating this mushroom blend to support healthy brain function.

Each serving of the mushroom complex delivers a powerful mix of beta-glucans, polysaccharides, proteins, triterpenes, and other nutritional compounds. Of course,it was a delight that all the ingredients were free from any artificial flavors or preservatives, giving me a clean, natural taste.

Additionally,I could take the pill with a meal, after one, or any time of the day. My experience with this mushroom formula was excellent, and I recommend it to anyone struggling with forgetfulness, mood swings, and low energy.


  • Easy to swallow
  • Quality ingredients
  • Enhances concentration
  • Non-GMO
  • Vegan friendly


  • Not as potent as other mushroom supplements

The Mushroom Latte Organic Coffee Extract with Grass-Fed Collagen from Everyday Dose

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This tasty mushroom coffee supplement is perfect for anyone with an aversion to the weird aftertaste that most formulations have. If you have an aversion to the weird aftertaste that most supplements have, then this mushroom coffee supplement is the one for you.

I would recommend it for its fresh and soothing creamy mushroom taste. Additionally, it doesn't come with the jitters, crashes, bloating, and digestive issues coffee has. The low-acidity coffee extract mixed with this mushroom magic will give you the pep you need in your step.

Apart from that, the ingredients are double extracted from the fruiting body of lion's mane mushrooms, among other nootropics. This super mushroom coffee promotes relaxation and calmness, which is important for a good night's sleep. Additionally, infused with the power of medicinal mushrooms, this supplement provides a balanced and focused start to your day.

With the best mushroom supplements for your immune system function, you won't have an issue with digestion, brain health, and blood pressure. I did notice a difference in overall health and alertness within a week of taking these supplements.


  • Great flavor
  • Blends well
  • High-quality
  • Low caffeine and acidity
  • Easy to digest


  • Induces headaches in the first week

Stonehenge Health Dynamic Mushrooms

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Formulated with a combination of comprehensive mushroom supplements, this brand delivers better immune function and energy boost. Of course, since it's derived from the best mushroom extracts, there is little debate that these supplements are healthy. While it might take a few weeks for the capsules to work, the mental clarity you get is unmatched.

I also realized how great these supplements are if you want to relax and have a whole night's sleep. If you're having difficulty falling asleep, these supplements work fast. For that reason, I find that it's best to take it at night. Of course, you will still wake up feeling very energized and notice a change in your general mood.

While it is recommended to take at least 2 pills a day, this might not be the right dosage for first-time users and anyone who suffers from heartburn. A lesser dosage still has the same effects, and you won't get debilitating heartburn in the first few weeks.


  • Improves mental clarity
  • Easy to swallow
  • No noticeable flavor


  • Contains additives
  • You might get heartburn

How to Choose the Best Mushroom Supplements

It is essential to choose the best mushroom supplement brand based on specific criteria to ensure optimal benefits and safety. Of course, since the differences are not immediately apparent, selecting the best brand can be a little daunting. However, here are some factors to consider if you want the best mushroom supplements.

a) Third-Party Testing

Third-party testing refers to other certified companies testing the mushroom supplements to ensure the quality and purity of the products. In the supplement industry, third-party testing and certifications ensure that the customer knows what they are getting in terms of identity, strengths (dosages), quality, and purity of the ingredients in the products.

If banned products are found in the supplements, there is usually an immediate recall. Additionally, like with many other supplement companies, the side effects are directly noted on the packaging.

b) Method of Extraction

The extraction method that yields mushroom supplements matters because it affects the potency. Using hot water extraction is the most common method.

Sometimes,the dual extraction method is used. This is the process of mixing both hot water and alcohol to extract the helpful compounds in mushroom powders. However, dual extractions are only used for mushroom tinctures.

Additionally, the hot water method ensures you get all the active and beneficial compounds from the mushrooms, like beta-glucans and triterpenes. You still get water and alcohol-soluble compounds with this method.

Because many mushrooms do not require dual extraction and may be adversely affected, it is essential to ensure that the appropriate solvent is utilized. Furthermore, since mushroom supplements are usually extracted in powder form, they have a long shelf life.

c) Mushroom Species

Different mushroom species offer different health benefits. Therefore, various types of mushrooms have different uses, depending on the type of health benefits you are interested in.For example, organic reishi mushroom is great for immune system function, organic Chaga mushrooms are ideal for lowering blood sugar levels, and lion's mane mushroom protects liver and kidney health.

Common species of mushrooms contain bioactive compounds that help with overall health. Of course, you can also get a supplement with a cocktail of all the mushroom species you prefer. Most supplements have at least 10 types of mushroom extracts within them. This will give you a broader range of benefits that will combat various problems.

Since mushroom supplements are considered dietary supplements, the health and wellness industry has formulated potent forms of these products for adaptive health benefits.

d) Form and Dosage

Different supplements come in various forms, with the most common being pills, powder, and mushroom tinctures.If pills or capsules are hard to swallow, you can use powder for easier consumption. So when searching for the best way to take mushroom supplements,ensure you select the form that's easiest to take.

You can determine the most convenient form by keeping powders, capsules, and other single-serve forms readily available. Of course, since supplements typically work best when paired with an established routine, you should choose a simple mushroom supplement to incorporate into your daily health regimen.

Additionally, it's important to remember that the potency of mushroom supplements varies depending on the species or blend. This is where the dosage comes into prevent any cases of overconsumption. Typically, the label contains the dosage of 1-3 pills a day for pill supplements and single-serve measurements for powdered supplements. Plus, it is recommended to stick to the dosage and not go above it, but you can always take less than the required.

e) Side Effects

Like most dietary products, most broad-spectrum mushroom supplements usually have potential side effects, and the common ones include:

  • Nausea
  • Headaches
  • Heartburn
  • Stomach upset
  • Dizziness
  • Itching
  • Rash

While most of these side effects usually resolve within the first few weeks, it isn't recommended that you continue to take them if the side effects persist. Additionally, you are required to discontinue use if any of the side effects become adverse, like vomiting or severe abdominal cramps.

Therefore, before buying these supplements, ensure to do enough research on the side effects and the potency. Remember, not everyone experiences side effects, and you might only experience mild forms of headaches or stomach upset.

f) Clinical Studies and Research

There are many mushroom supplements on the market, but not all are backed by scientific research. Additionally, not all mushrooms are to be consumed. Therefore, before you buy a supplement, look at the ingredient list, and find any studies you can that prove their efficacy and safety when it comes to consumption. While medicinal mushrooms exhibit a wide range of important health benefits, clinical trials must be conducted to confirm safe use and perks.

Research about the bioactive compositions and nutritional values of different mushrooms has increased significantly in the past several years. These studies have yielded results that highlight the benefits, like the high content of dietary fiber, amino acids, and low levels of fats.

Frequently Asked Questions About the Best Mushroom Supplements

i) Which mushroom supplement is best for me?

The best mushroom supplement is the NutriFlair Mushroom Supplement. Any mushroom supplement with reishi mushrooms is an excellent start because they are the most studied, calm the nerves, reduce stress, and boost the immune system. Often called the "queen of mushrooms," you shouldn't have any problem taking this mushroom supplement.

ii) Do mushroom supplements work?

Yes, they do. Medicinal mushrooms contain nutrients that are known for their healing capabilities. Their uses have been studied and backed up by research in the past and present. Furthermore, mushrooms have always been documented as having superfood status that is great for gut health and the immune system.

iii) Which mushroom gives the most energy?

Cordyceps mushrooms are known to contain various bioactive compounds, including polysaccharides, nucleosides, and amino acids, which contribute to their potential health benefits. These compounds are believed to support the body's energy production and overall well-being.

One of the key bioactive compounds in cordyceps mushrooms is adenosine, a nucleoside that plays a role in the body's energy metabolism. Adenosine helps in the production of adenosine triphosphate (ATP), which is the primary energy currency in cells. By supporting ATP production, cordyceps mushrooms may help enhance energy levels and reduce fatigue.

iv) What is the best mushroom for aging?

When it comes to aging, certain mushrooms are believed to offer potential health benefits due to their nutritional content and bioactive compounds. One mushroom that is often mentioned for its potential anti-aging properties is the Reishi mushroom (Ganoderma lucidum).

Reishi mushrooms are highly regarded in traditional Chinese medicine and have been used for centuries to promote longevity and overall well-being. They are known for their adaptogenic properties, meaning they may help the body adapt to stress and support a balanced immune system. Reishi mushrooms are rich in antioxidants, such as triterpenes and polysaccharides, which are believed to contribute to their potential anti-aging effects by combating oxidative stress and inflammation.

v) What mushroom is best for inflammation?

One of the most well-known mushrooms for its potential anti-inflammatory properties is the Turkey Tail mushroom (Trametes versicolor). Turkey Tail is a common mushroom found in many parts of the world and has been studied extensively for its medicinal properties.

Turkey Tail mushrooms are rich in various bioactive compounds, including polysaccharides like beta-glucans and triterpenoids, which are believed to contribute to their anti-inflammatory effects. These compounds may help modulate the immune system and reduce inflammation in the body.

vi) What are the best mushroom supplements for focus and memory?

Mushroom supplements have been associated with better cognitive health and function. Specifically, those extracted from Lion's Mane, Reishi, and Chaga mushrooms are effective for focus and memory. The best mushroom supplements for focus and memory include the Genius Mushroom Supplement and FreshCap, Ultimate Mushroom Complex Capsule.

vii) What is the best mushroom mix for the brain?

When it comes to mushroom supplements for brain health, a mix of Lion's Mane (Hericium erinaceus) and Cordyceps (Ophiocordyceps sinensis) mushrooms is often considered one of the best combinations.

Lion's Mane is well-regarded for its potential benefits in supporting cognitive function and brain health. It contains compounds called hericenones and erinacines, which have been studied for their neuroprotective and nerve-regenerating properties. These compounds may support the growth and repair of nerve cells, which can be beneficial for memory, learning, and overall brain function.

Cordyceps mushrooms have been traditionally used for their adaptogenic properties and their potential to improve energy and stamina. While not specifically a brain-focused mushroom, Cordyceps' ability to support energy levels and overall well-being can indirectly contribute to improved mental clarity and focus.

viii) How long does it take for mushroom supplements to work?

The time it takes for mushroom supplements to work can vary depending on several factors, including the individual, the specific mushroom supplement, the dosage, and the intended health benefit. In some cases, people may start noticing subtle effects relatively quickly, while for others, it may take several weeks or even months to experience noticeable changes.

The Bottom Line:

For people who want to improve their health naturally, these wonderful fungi have become a go-to supplement. People are clamoring for mushrooms because of their therapeutic and functional properties, and it is undeniable that these adaptable marvels are making rapid success in the world of natural health supplements. Furthermore, many are relying more and more on natural products for their well-being, so it isn't a surprise that the mushroom revival is a hit.

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