Skip to main content
Read about

Top 12 Best Lysine Supplements

Tooltip Icon.
Written by Andrew Le, MD.
Medically reviewed by
Last updated June 5, 2024

Try our free symptom checker

Get a thorough self-assessment before your visit to the doctor.

Lysine is an essential amino acid involved in many physiological functions of the human body, primarily as a precursor to proteins. It is essential for bone formation and bone marrow, absorption of vitamin B12, and production of some red blood cells. Lysine, on the other hand, is a naturally occurring amino acid and can be obtained from foods that are rich in protein, such as meat, fish, and dairy products, but for those who do not get adequate amounts of lysine in their diets, there are supplements available. That is where lysine supplements come in handy.

Lysine supplements are in form of capsules, tablets and powders with the capsules being the most popular and easily used form. These are often employed as immunomodulators, ergogenic aids, and for decreasing the incidence and duration of cold sore outbreaks. However, it must be noted that not all the lysine supplements in the market are the same and selecting the appropriate supplement is crucial.

Top 3 Best Lysine Supplements

  1. Nutricost L-Lysine 1000mg
  2. Bronson L-Lysine Defense Immune Support Complex
  3. Nature Made L-Lysine 1000 mg

We realize that it may be difficult for you to determine which lysine supplement is ideal for you, given the numerous ones available in the market today. But we have found out the details for the best lysine supplements that are available in the market. These supplements have been recommended according to their efficiency, quality, and customer feedback. If you are interested in the lysine supplement for the enhancement of your immune system, the improvement of skin condition or the treatment of cold sores, you can find it on our list. Well, now, let us proceed with the recommended lysine supplements.


Nutricost L-Lysine 1000mg

The Editor's Choice

Nutricost L-Lysine 1000mg excels in quality and adapts to diverse dietary goals. Perfect for bolstering immunity, boosting collagen, and ensuring overall well-being. A hassle-free, trustworthy supplement catering to your health needs.

See Price on Amazon

Are you in the search for a good L-Lysine supplement? The Nutricost L-Lysine 1000mg pack contains 120 tablets, and this product may be the answer to your needs. It is ideal for people who take mindful of their diets, especially because it does not contain any form of gluten, GMOs, and it is vegetarian.

Pros

  • Each tablet delivers a potent dose of 1000mg L-Lysine, ensuring you get the maximum benefits with each serving.
  • Gluten-free formulation caters to individuals with gluten sensitivities or those following a gluten-free diet.
  • Non-GMO ingredients offer peace of mind for those concerned about the sourcing and quality of their supplements.
  • Vegetarian-friendly composition aligns with diverse dietary preferences and lifestyles.

Cons

  • Some users may find the tablet size larger than preferred, though it's manageable for most.
  • As with many supplements, results may vary among individuals, and it may take consistent use over a period of time to experience noticeable benefits.

Nutricost L-Lysine 1000mg is one of the best choices on the market because it is of high quality and can be a part of many diets. In general, this supplement is beneficial for its ability to provide essentials for everyday support and health such as enhanced immune support or boosting collagen production.

See price on Amazon

If you’re in search of an effective Lysine supplement that also boosts the immune system then the Bronson L-Lysine Defense Immune Support Complex is highly recommended.

Pros

  • The L-Lysine Defense Complex formula contains L-Lysine, Olive Leaf, Garlic, Vitamin C, and Zinc, which work together to provide superior immune support.
  • The highest quality formula is laboratory tested NON-GMO, and all Bronson products are tested in their state-of-the-art cGMP registered facility in New York.
  • Bronson Vitamins have been consistently mentioned by top medical professionals since their inception in 1960, so you can trust their product quality.

Cons

  • The capsules are relatively large, which may be difficult for some people to swallow.
  • The garlic flavor may be unpleasant for some users.
  • Some customers have reported discoloration in the tablets after a few months.

Personally we have found the Bronson L-Lysine Defense Immune Support Complex to work effectively in boosting our immune system. We can see that L-Lysine, Olive Leaf, Garlic, Vitamin C and Zinc for the immune system is very complete, and we also like that this product is laboratory tested NON-GMO.

Despite the size of the capsules being relatively large, we saw it fit to take them with ample amounts of water to help us swallow them easily. However, some users may consider them difficult to take. Also, the garlic flavor is a little strong for our tastes, but it was not a problem for us.

In conclusion, the Bronson L-Lysine Defense Immune Support Complex should go to anyone who is in the market for a supreme Lysine supplement that is built to enhance the function of your immune system.

See Price on Amazon

The Nature Made L-Lysine 1000 mg tablets are an ideal L-Lysine supplement for those seeking a high-quality supplement.

Pros

  • Provides 1000 mg of L-Lysine in just one daily tablet
  • Gluten-free with no color added, no artificial flavors, and no preservatives
  • Recommended by pharmacists as the #1 vitamin and supplement brand*

Cons

  • Tablet is quite large and may be difficult to swallow for some
  • Exposure to heat or sunlight may lead to melting/damage of the product, so customers should be available during delivery
  • Some users may need to take a higher dosage than 1000 mg for optimal results

We have been using Nature Made’s L-Lysine 1000 mg tablets for a couple of weeks now and these few weeks have made us more energetic. It is convenient to take one tablet per day and we liked that they are gluten-free and contain no colors, flavors, or preservatives.

However, we did find that the tablet was large and relatively hard to swallow, which may prove to be problematic to those who have issues with swallowing pills. Furthermore, we were afraid that the product could melt or be damaged in some way by the heat or sun exposure while in transport, so we ensured that we were available to receive the product.

All in all, we can highly recommend Nature Made’s L-Lysine 1000 mg tablets to anyone in need of a good quality L-Lysine for boosting their health and levels of energy.

*According to a survey that involved pharmacists who recommended branded vitamins and supplements. It is important to note that these statements have not been approved by the Food and Drug Administration. This product does not claim to be a cure, treatment, prevention, or diagnosis of any disease.

See Price on Amazon

If you are seeking for good lysine supplement, you will not go wrong with Pure Encapsulations L-Lysine Supplement.

We have tried this supplement our self and have felt an improvement in not only our immune system but our health in general. The capsules are smooth and the supplement does not contain allergens, artificial or unwanted compounds, or genetically modified organisms.

The Pure Encapsulations L-Lysine Supplement is also beneficial to the health of the gums and lips and helps minimize the occurrence of canker sores.

All in all, we would recommend this lysine supplement for anyone who wants to enhance their immune system and achieve superior health.

Please always seek medical advice from your doctor before using any new supplement, particularly if you are pregnant, a lactating mother, or if you are on medication.

Pros

  • Essential amino acid that supports the body's natural defenses
  • Provides nutritional support to help maintain immune function and immune system
  • Maintains arginine production and supports the body's natural immune defenses

Cons

  • May not be suitable for vegans or vegetarians
  • Some users may experience mild gastrointestinal discomfort
  • May interact with certain medications, so consult a doctor before use
See Price on Amazon

For anyone who is trying to find a good lysine supplement, NOW L-Lysine Hydrochloride Supplement is a product that can be considered.

In the past few weeks, we have been taking this supplement and we are realizing improvements in our general well-being and vitality. It is convenient to take tablets, and we like that the product is vegan and does not contain any allergenic components such as soy or gluten.

Something to note is that some people may have mild gastrointestinal upset after taking this supplement. Furthermore, some patients may also complain that the tablets are too big to be swallowed easily. However, these issues are relatively minor and shouldn’t affect you from trying NOW L-Lysine Hydrochloride Supplement.

All in all, we can say that this product is highly recommended for those who seek for an effective lysine supplement. It’s then very cheap, efficient and comes from a company that has been around for more than thirty years.

Pros

  • Double strength vegan tablets/essential amino acid: Lysine is an essential amino acid that must be obtained through diet or supplementation.
  • SUPPORTS COLLAGEN SYNTHESIS: Necessary for the production of all proteins in the body and is required for the maintenance of the structural proteins collagen and elastin.
  • Certifications/classifications: Soy-free, non-GMO, vegan/vegetarian, nut-free, made without gluten, dairy-free, egg-free, kosher.

Cons

  • Some people may experience mild stomach discomfort when taking this supplement.
  • Some users may find the tablets too large and difficult to swallow.
  • Natural color variation may occur in this product.
See Price on Amazon

If you seeking a supplement for healthy calcium metabolism and a healthy stress response.

For the past few months, we have been using this supplement and it has greatly improved the health of our body. The capsules are convenient to swallow and we also like it that the product is certified Non-GMO and Gluten free. We also appreciate that the supplement works to prevent glycation since it is one of the several processes that contribute to the aging process.

However, it should be noted that the capsules are relatively large, which can be problematic for those who do not like swallowing large pills. Also, the supplement may not be in the best interest of those with kidney or liver complications. It is also important to note that before the effects begin to show, it might take some time.

In conclusion, we highly recommend Life Extension L-Lysine Supplement to anybody who wants to improve his/her health.

Pros

  • The supplement helps inhibit glycation, which is one of several factors that lead to the physiological effects of aging.
  • It's sourced using only the finest raw ingredients with the purity and potency your body deserves.
  • The product is certified non-GMO and gluten-free.

Cons

  • The capsules are big, which may be difficult to swallow for some people.
  • The supplement may not be suitable for people with kidney or liver problems.
  • It may take some time before you start noticing any effects.
See Price on Amazon

If you are interested in an L-Lysine NonGMO Dietary Supplement, we suggest that you purchase the Superior Labs L-Lysine NonGMO Dietary Supplement as it helps in boosting and supporting the immune system and the respiratory system.

L-Lysine NonGMO Dietary Supplement that we purchase from the Superior Labs has proved to be effective in enhancing the immune and respiratory system within the time that we have been using it. The 500 mg pure active L-Lysine has assisted us in building muscle mass and in decreasing the time it takes to recover after a good session.

There is no doubt about the quality of the product because it does not contain any chemical compounds and it is being made in 3rd party certified NSF certified facilities. We acknowledge the fact that the product contains no other binder such as stearates, dioxides, glycerides or fillers that most manufacturers add to their products to make production cheaper, faster and easier.

However, some of the users complained that the capsules were not sealed properly and some other capsules contained some powdered residue. Also, it is an unflavored product, which could be an issue for people who prefer to take flavored supplements. Lastly, the package dimensions are 4. 8 x 3. 39 x 2. 64 inches, which might be big for some people who like small packages.

In general, the Superior Labs L-Lysine NonGMO Dietary Supplement is a wonderful product for people who want to strengthen their immunity and respiratory system. Since the product is pure, high quality and effective then it will be worth using it.

Pros

  • The 500 mg pure active L-Lysine supports calcium absorption and immune function to maintain muscle mass and promote well-being.
  • L-Lysine can support repair and restoration of muscle tissue. This helps to maintain muscle mass and reduce recovery time from workouts.
  • The product is 100% free of contaminants and produced in 3rd party certified NSF certified facilities.

Cons

  • Some users have reported that the capsules weren't closed properly and there was some loose powder on some of the other capsules.
  • The product is unflavored, which may be a downside for those who prefer flavored supplements.
  • The package dimensions are 4.8 x 3.39 x 2.64 inches, which may be too large for those who prefer smaller packaging.
See Price on Amazon

We highly suggest getting the NOW Supplements L-Lysine because this is an amino acid that is actually required for the synthesis of all proteins in the body. It maintains the health of tissues that connect and support the body as well as the calcium category and might aid the immune as well as cardiovascular systems in their functioning.

NOW Supplements L-Lysine is something that we have been taking for quite some time and we have definitely seen positive changes in our health. The tablets are portable and do not cause any bad smell or funny taste in the mouth. We are delighted by the fact that the product is Non-GMO, Dairy-free, Egg-free, Gluten-free, made without nuts or soy, and vegan/vegetarian friendly.

We understand that the tablets come in large sizes and this may pose a challenge to some individuals as they find it hard to swallow the tablets. In addition, some users may suffer from stomach pains after consuming the supplement. One must understand that people with kidney and liver complications should consult a doctor before taking this supplement.

In conclusion, NOW Supplements L-Lysine is one of the best supplements on the market, and we encourage people to try it if they want to improve their well-being. The product is cheap, efficient, and manufactured by a company that has been in the market for more than half a century.

Pros

  • Supports healthy connective tissue and calcium absorption
  • May help to support a healthy immune system and proper cardiovascular function
  • Non-GMO, Dairy Free, Egg Free, Made without Gluten, Nut Free, Soy Free, Vegan/Vegetarian

Cons

  • Large tablets may be difficult to swallow for some
  • May cause stomach discomfort for some users
  • May not be suitable for those with kidney or liver disease
See Price on Amazon

If you are interested in taking a lysine supplement for your immune system, we suggest that you try Amazon Elements Lysine Complex with Vitamin C.

We have been using Amazon Elements Lysine Complex with Vitamin C for the past several weeks and feel that our bodies immune systems have benefited. It is convenient to use as a supplement, and we like to know that the product contains some natural compounds to boost our immune system. However, we did find that there was a faint smell when the bottle was first opened, but the smell was not too strong. We also had to ensure that the supplement did not get spoiled by heat or direct sunlight during storage. All in all, we are happy with the purchase and can refer this product to other individuals in search of a healthy boost to their immunity system.

Pros

  • The supplement contains a variety of harvested ingredients, including echinacea, bee propolis, and licorice root, in addition to lysine and vitamin C, to support immune health.
  • The product is vegetarian, gluten-free, and doesn't contain any artificial colors, flavors, or chemical preservatives.
  • Amazon Elements thoroughly tests every batch of product for quality and safety.

Cons

  • The supplement may have a slight to moderate smell that is similar to tree sap due to the bee propolis ingredient.
  • Exposure to heat or sunlight may lead to melting or damage of the product, so customers are expected to be available during the product delivery.
  • The pills may be a bit large and difficult to swallow for some people.
See Price on Amazon

Solgar L-Lysine is another great lysine supplement and is a great source of L-Lysine 1000 mg.

We have been taking Solgar L-Lysine 1000 mg for a couple of weeks now and really have observed some positive changes in the skin and lips. The tablets can be easily swallowed and are readily assimilated by the body.

The tablets are relatively large in size but we have not had any problems in swallowing them at all. However, they may be hard to swallow to some of the users. The recommended dose of two tablets a day may also be uncomfortable for some users.

All in all, Solgar L-Lysine 1000 mg got our seal of approval and we suggest it to any individuals who would like to incorporate lysine into their dietary plan. The product is vegan and does not contain many allergens, which makes it appropriate for many people.

Pros

  • The formulation of Solgar L-Lysine 1000mg provides the body with Free Form L-Lysine in order to promote optimal absorption and assimilation into the body’s systems.
  • L-Lysine is an essential amino acid that contributes to the body being able to support the health of skin tissue.
  • Suitable for vegans – All tablets are non-GMO and certified gluten-free. They are also free of wheat, dairy, soy, yeast, sugar, sodium, artificial flavors, sweeteners, preservatives, and colors.

Cons

  • The tablets are quite large and may be difficult to swallow for some people.
  • The recommended dosage is two tablets per day, which may be inconvenient for some users.
  • Some users may experience mild stomach upset when taking this supplement.
See Price on Amazon

We recommend the Horbäach L-Lysine supplement to be bought because it is affordable and has optimum quality.

We have been taking the Horbäach L-Lysine supplement for a number of months now and have seen the general well-being of our health improve greatly. The supplement is in the form of capsules and does not have any side effects as long as it is used as recommended.

The fact that this L Lysine is brewed in a high dosage per serving means that this is sufficient for boosting my immune system, skin, and other general body health checks. It also contains nutritional supplement that is vegetarian, non-GMO, and gluten-free depending on our dietary needs.

Overall, only a small issue related to the size of the caplets that may be difficult to swallow for some individuals is found in this supplement. Moreover, they might not be individuals who should use the supplement due to allergies or restrictions of their diets. But we do believe that this supplement can be very useful in helping players train and perform better, despite its disadvantages.

All in all, the Horbäach L-Lysine supplement is uniquely recommended to anyone struggling with overall health issues.

Pros

  • The supplement delivers a high dose of L-Lysine per serving, which is essential for overall health.
  • The caplets are coated, making them easy to swallow.
  • The supplement is vegetarian, non-GMO, and gluten-free.

Cons

  • The caplets are quite large, which may be difficult for some people to swallow.
  • The supplement may not be suitable for those with certain allergies or dietary restrictions.
  • The price point may be higher than some other L-Lysine supplements on the market.
See Price on Amazon

The NOW Supplements, L-Lysine is worth a try especially if you are in the market for a good lysine supplement.

We have been taking NOW Supplements, L-Lysine for about few weeks now and our skin especially the face has really changed for the better. The capsules that are used are small and easy to swallow and also unlike most supplements we have used before they do not have a bad aftertaste in your mouth.

We understand that this product is Non-GMO, Halal, and Soy Free which makes this product suitable for consumption by individuals with special diets. Furthermore, it plays a role in collagen synthesis and may maintain and promote immunity as well as proper cardiovascular function.

However, it needs to be mentioned that it may have some side effects and is not recommended for people with certain health issues. Others may also develop some mild side effects like nausea and vomiting or have loose stools. Lastly, vegans may want to look for other products as this product is not suitable for vegans.

All in all, we can comfortably endorse NOW Supplements, L-Lysine for anyone interested in promoting skin health while at the same time boosting the immune and cardiovascular systems.

Pros

  • Supports collagen synthesis for healthy skin and connective tissues.
  • May help to support a healthy immune system and proper cardiovascular function.
  • Non-GMO, Halal, Soy Free.

Cons

  • May not be suitable for those with pre-existing medical conditions.
  • Some users may experience mild side effects such as stomach upset or diarrhea.
  • May not be suitable for vegans.

Buying Guide

When looking for the best lysine supplement, there are a few key features to consider. Here are some factors to keep in mind when making your purchase:

1. Dosage

The first aspect to look at is the amount of lysine in the supplement. The dosage of lysine should range from 1,000 to 3,000 mg per day and the chosen supplement should contain it.

2. Form

Lysine supplements are available in the form of capsules, tablets, powders, and liquids. It is essential to select a form that does not inconvenience you and one that you can easily accomplish.

3. Purity

When selecting a lysine supplement, ensure that it is third-party certified to be pure and fit for human consumption. Try to identify products, which received meals from independent laboratories and proved their high quality and purity.

4. Other Ingredients

Read other contents that may be present in the supplement and check the label for them. Some products may contain other vitamins or minerals that may enhance the effects of lysine while other products may contain bulking agents or other additives.

5. Price

However, although price should not be your leading criterion, affordable lysine supplements should be your aim. Search for the right price range for the brand and product you require to ensure you get a good price deal.

Frequently Asked Questions

1. What are the benefits of taking Lysine supplements?

Lysine supplements are specifically used to manage and prevent cold sore formations caused by the herpes simplex virus. Moreover, lysine can help boost the immune system and strengthen collagen and the absorption of calcium.

2. How much Lysine should I take daily?

The daily requirement for lysine may also differ depending on age, sex, body weight, condition, and other factors. Nonetheless, most adults can consume up to 3 grams of lysine daily without experiencing any ill effects.

3. What are the different types of Lysine supplements available?

Lysine is obtainable in the form of capsules, tablets, powders, and liquids. It is also important to note that some of the products may also have other natural ingredients like vitamin C and zinc added to them.

4. Which brand of Lysine supplement is the most effective?

Lysine supplements are not to be the same effective in all cases since the required time to intake the supplement will depend on the need and preference of an individual. Consumers should be very careful when selecting a brand to use and also they should consult a doctor before using any new supplement.

5. Is it safe to take Lysine supplements daily?

Lysine supplements are not known to have significant side effects when they are used in the recommended dosages. However, lysine in large doses can induce gastrointestinal symptoms including nausea and diarrhea. It is advisable to use lysine within the recommended dosage levels and consult a doctor on the right time to take lysine supplements.

6. Can Lysine supplements help prevent viral shedding?

In terms of its effects on the herpes simplex virus, studies indicate that lysine supplements can actually help slow down the viral shedding process in patients. However, carrying out more investigation about the subject will help in the attempts to find out what the most effective dosage and time span for this treatment should be.

Affiliate Disclosure:
the links provided may earn us a small commission at no additional cost to you if you choose to purchase the recommended product. This support allows our research and editorial team to continue providing high-quality recommendations. As a participant in the Amazon Services LLC Associates Program, an affiliate advertising initiative, we are able to earn advertising fees through providing links to products on Amazon.com. Please rest assured that we only recommend high-quality products.

Share your story
Once your story receives approval from our editors, it will exist on Buoy as a helpful resource for others who may experience something similar.
The stories shared below are not written by Buoy employees. Buoy does not endorse any of the information in these stories. Whenever you have questions or concerns about a medical condition, you should always contact your doctor or a healthcare provider.
Jeff brings to Buoy over 20 years of clinical experience as a physician assistant in urgent care and internal medicine. He also has extensive experience in healthcare administration, most recently as developer and director of an urgent care center. While completing his doctorate in Health Sciences at A.T. Still University, Jeff studied population health, healthcare systems, and evidence-based medi...
Read full bio

Was this article helpful?

Tooltip Icon.