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Top 10 Best Niacinamide Serums for Reducing Redness

Written by Andrew Le, MD

UpdatedOctober 23, 2024

Many individuals suffer from persistent skin redness due to conditions like rosacea, acne, and irritation from environmental factors. This persistent redness can lead to discomfort and a lack of confidence, as finding effective solutions can be challenging.

Despite numerous skincare products on the market, many fail to effectively reduce redness, often exacerbating the problem with harsh ingredients. This leads to frustration, wasted time, and increased skin irritation, leaving individuals desperate for a reliable solution.

Fortunately, incorporating niacinamide into your skincare routine can offer substantial benefits. Research has shown that niacinamide has anti-inflammatory effects making it a suitable component in skincare products to reduce skin redness and irritation. Here are the best niacinamide serums that can help you achieve the clear, radiant skin you’ve longed for.

Niacinamide for Skin Health

Niacinamide has gained significant attention in cosmetic dermatology due to its diverse range of beneficial effects on the skin. Recent studies have elucidated the various mechanisms through which niacinamide exerts its effects, making it a key ingredient in skincare formulations aimed at improving skin health and appearance.

Anti-Inflammatory Mechanisms

Niacinamide, a form of vitamin B3, is well-known for its significant anti-inflammatory properties. According to previous research, niacinamide reduces redness by inhibiting the activity of pro-inflammatory cytokines, such as interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-α), which are molecules that promote inflammation.

This suppression is vital in calming the skin and reducing the redness associated with various skin conditions, including acne.

Enhancement of Skin Barrier Function

Niacinamide plays a crucial role in improving the function of the skin barrier. One study observed that a niacinamide-containing moisturizer significantly enhanced the stratum corneum barrier function in subjects with rosacea.

This improvement was evidenced by increased stratum corneum hydration and reduced transepidermal water loss (TEWL). Enhanced barrier function is essential for maintaining skin hydration and protecting against environmental irritants.

Reduction of Hyperpigmentation

Niacinamide inhibits the transfer of melanosomes from melanocytes to keratinocytes, thereby reducing hyperpigmentation. One study demonstrated that niacinamide significantly decreases melanin production and improves skin tone when used in combination with other active ingredients. This mechanism makes niacinamide an effective treatment for melasma and age spots.

Anti-Aging Effects

Niacinamide has been extensively studied for its anti-aging and anti-pigmentation effects. According to a study, niacinamide’s role in restoring cellular NAD+ pools and mitochondrial energetics is fundamental to its anti-aging properties. By boosting NAD+ levels, niacinamide enhances cellular repair processes and energy metabolism, vital for maintaining youthful skin.

Top 10 Best Niacinamide Serums

We have researched the top 10 best niacinamide serums and selected them based on their effectiveness, quality, and user reviews. These serums enhance skin health by reducing redness, improving skin barrier function, and addressing hyperpigmentation and signs of aging.


COSRX Niacinamide 15%

COSRX Niacinamide 15%

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COSRX Niacinamide 15% Face Serum is a potent skincare solution designed to address various skin concerns, including redness relief, enlarged pores, and discoloration. With a powerful concentration of 15% niacinamide, this serum effectively improves skin texture, reduces pore size, and brightens the complexion.

The addition of Zinc PCA helps regulate sebum production and prevent breakouts, making it suitable for oily and acne-prone skin. This serum is formulated with skin-friendly ingredients and adheres to COSRX's high standards for hypoallergenic and cruelty-free products.

Pros

  • High concentration of 15% niacinamide helps to minimize enlarged pores and refine uneven skin tone.
  • Zinc PCA included in the formula aids in preventing breakouts and controlling excess oil production.
  • The serum is free from parabens, sulfates, and artificial fragrances, making it suitable for sensitive skin.
  • Hypoallergenic and dermatologist-tested, ensuring it is gentle and safe for various skin types.
  • It helps fade dark spots and improves overall skin radiance and texture.
  • The lightweight, non-greasy texture makes it easy to apply and layer with other skincare products.
  • Not tested on animals, aligning with ethical and cruelty-free beauty standards.

Cons

  • The 15% niacinamide concentration may be too potent for some, potentially causing initial irritation for sensitive skin types. It's advisable to perform a patch test before incorporating it fully into your routine.
  • Some users may find the serum slightly drying, necessitating the use of a good moisturizer afterward.
  • A few users might experience mild burning when the serum comes into contact with any skin imperfections.

Anua Niacinamide 10% + 4% Tranexamic Acid Serum

Anua Niacinamide 10% + 4% Tranexamic Acid Serum

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Anua 10% Niacinamide + 4% Tranexamic Acid Serum is a comprehensive skincare solution designed to address multiple skin concerns, particularly redness and discoloration. This serum combines 10% niacinamide with 4% tranexamic acid to effectively brighten the skin, reduce the appearance of dark spots, and minimize enlarged pores.

Additionally, the formula is enriched with ceramides and hyaluronic acid to protect the skin barrier, provide deep hydration, and soothe sensitive skin. The serum's lightweight, non-greasy texture makes it easy to incorporate into both morning and evening skincare routines.

Pros

  • High concentration of 10% niacinamide helps to minimize enlarged pores and refine uneven skin tone.
  • Tranexamic acid effectively targets and reduces dark spots and discoloration.
  • The inclusion of ceramides and hyaluronic acid protects the skin barrier and provides deep hydration.
  • The serum is free from parabens, sulfates, and artificial fragrances, making it suitable for sensitive skin.
  • Hypoallergenic and dermatologist-tested, ensuring it is gentle and safe for various skin types.
  • Helps reduce redness and improve overall skin radiance and texture.
  • The lightweight, non-greasy texture makes it easy to apply and layer with other skincare products.
  • Not tested on animals, aligning with ethical and cruelty-free beauty standards.

Cons

  • The 10% niacinamide concentration may be too potent for some, potentially causing initial irritation for sensitive skin types. It's advisable to perform a patch test before incorporating it fully into your routine.
  • Some users may find the serum slightly sticky, which might be uncomfortable for those with oily skin.
  • A few users might experience mild burning when the serum comes into contact with any skin imperfections.

Kiehl's Ultra Pure High-Potency 5.0% Niacinamide Serum

Kiehl's Ultra Pure High-Potency 5.0% Niacinamide Serum

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Kiehl's Ultra Pure High-Potency 5.0% Niacinamide Serum is a targeted skincare solution designed to address excess oil and shine while helping to minimize imperfections for a natural glow. This serum is specifically formulated to reduce redness and improve the overall appearance of the skin by balancing the skin's natural surface oils.

With a concentration of 5.0% niacinamide, it works effectively to visibly brighten skin tone, smooth texture, and reduce the appearance of blemishes, making it suitable for individuals with oily or acne-prone skin. Additionally, the serum is unscented and paraben-free, ensuring it is gentle enough for daily use without causing irritation.

Pros

  • Contains 5.0% niacinamide, which helps to visibly brighten skin tone and reduce redness.
  • Effectively balances the skin's natural surface oils, reducing excess oil and shine.
  • Helps minimize the appearance of imperfections and blemishes, leaving the complexion smooth and glowy.
  • Lightweight and fast-absorbing formula that does not leave a greasy residue.
  • Unscented and paraben-free, making it suitable for sensitive skin.
  • Suitable for use both in the morning and at night, and can be layered with other skincare products.
  • Comes in a convenient dropper bottle for easy and precise application.

Cons

  • Some users may find the serum slightly sticky upon application.
  • The lightweight formula might not provide enough hydration for very dry skin types, necessitating an additional moisturizer.
  • A few users with extremely sensitive skin may experience initial irritation, making a patch test advisable before full use.

Good Molecules Niacinamide Serum

Good Molecules Niacinamide Serum

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Good Molecules Niacinamide Serum is a versatile skincare product designed to improve your skin's tone and texture. This serum contains 10% niacinamide, known for its ability to refine skin tone, minimize the appearance of pores, and enhance the skin's barrier function. It is particularly beneficial for those with acne-prone skin, helping to reduce breakouts and redness. Additionally, the serum is formulated to be hydrating and non-drying, making it suitable for daily use without causing irritation. Its lightweight, unscented formula absorbs quickly, making it an excellent addition to any skincare routine for a smoother and more even complexion.

Pros

  • Contains 10% niacinamide, which helps to refine skin tone and texture while reducing redness.
  • Effective for acne-prone skin and helps minimize breakouts and inflammation.
  • Hydrating and non-drying formula supports a healthy skin barrier.
  • Lightweight, non-greasy, and quickly absorbing texture.
  • Unscented and free from parabens, making it suitable for sensitive skin.
  • Cruelty-free and vegan, aligning with ethical beauty standards.

Cons

  • Some users may find the 10% concentration of niacinamide too strong, potentially causing initial irritation for sensitive skin types. A patch test is recommended.
  • The serum can leave a slightly tacky finish on the skin, which might not be preferred by everyone.
  • A few users have reported experiencing breakouts when first incorporating the serum into their routine, suggesting it may not be suitable for all skin types.

Advanced Clinicals 5% Niacinamide Serum

Advanced Clinicals 5% Niacinamide Serum

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Advanced Clinicals 5% Niacinamide Serum is a powerful yet gentle solution designed to enhance your skincare routine. This serum features a 5% concentration of niacinamide, an effective ingredient known for its ability to brighten the skin and reduce redness.

Infused with hyaluronic acid, ferulic acid, aloe vera, and natural fruit extracts, this serum not only hydrates but also helps to clarify and even out skin tone. It is particularly beneficial for those dealing with dark spots, age spots, and signs of aging.

Dermatologist and allergy tested, this cruelty-free formula is manufactured in a federally audited lab in the USA, ensuring high quality and ethical sourcing.

Pros

  • Contains 5% niacinamide, which is effective for brightening and reducing redness.
  • Infused with hyaluronic acid, ferulic acid, aloe vera, and fruit extracts for added hydration and skin nourishment.
  • Helps reduce the appearance of fine lines and wrinkles, providing a smooth, hydrated finish.
  • Dermatologist and allergy tested, making it safe for all skin types.
  • Cruelty-free and manufactured in a federally audited lab in the USA.
  • Lightweight and easily absorbed, leaving no sticky residue.
  • Suitable for daily use, both morning and night.

Cons

  • Higher concentrations of niacinamide can cause skin irritation for some users.
  • The glass dropper bottle can be fragile and less convenient compared to pump dispensers.
  • Some users may find the initial texture slightly tacky before fully absorbing.
  • While effective, results can vary and may require consistent use over time to see significant improvements.

The Ordinary Niacinamide 10% + Zinc 1%

The Ordinary Niacinamide 10% + Zinc 1%

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The Ordinary Niacinamide 10% + Zinc 1% serum is a powerful and affordable skincare solution designed to target and reduce the appearance of skin blemishes and congestion. This serum combines the benefits of high-strength niacinamide (vitamin B3) and zinc PCA to help balance sebum activity, making it particularly beneficial for those with oily or acne-prone skin.

Niacinamide is known for its anti-inflammatory properties, which help reduce redness and soothe the skin, while zinc supports skin healing and reduces the formation of new blemishes. The lightweight, water-based formula absorbs quickly into the skin, leaving it feeling smooth and refreshed without any greasy residue.

Pros

  • Contains 10% niacinamide, which is effective in reducing redness and soothing the skin.
  • Includes zinc PCA, which helps to regulate sebum production and minimize breakouts.
  • Lightweight, water-based formula that absorbs quickly without leaving a greasy residue.
  • Cruelty-free and vegan, with no alcohol, gluten, nuts, oils, silicones, parabens, or sulfates.
  • Suitable for daily use, both morning and night, and works well under other skincare products and makeup.
  • Helps to improve overall skin texture and clarity, leaving the skin looking brighter and more even-toned.

Cons

  • The initial texture can feel slightly sticky before fully absorbing into the skin.
  • Some users may experience a tingling sensation upon application, which might not be suitable for very sensitive skin.
  • Results can vary, and consistent use over several weeks is often required to see significant improvements.
  • The dropper bottle packaging can be less convenient and more prone to spills compared to pump dispensers.

Naturium Niacinamide Face Serum 12% Plus Zinc 2%

Naturium Niacinamide Face Serum 12% Plus Zinc 2%

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Naturium Niacinamide Face Serum 12% Plus Zinc 2% is a powerful skincare solution designed to address multiple skin concerns, including enlarged pores, uneven texture, and excess oil production. Formulated with a high concentration of niacinamide (vitamin B3) and zinc PCA, this serum helps to visibly refine the skin's complexion, making it smoother and more radiant. Additionally, it effectively reduces redness and soothes the skin, making it an excellent choice for those with sensitive or acne-prone skin. The inclusion of hyaluronic acid and vitamin E ensures that the skin remains hydrated and nourished, promoting a healthy, youthful appearance. This serum is suitable for daily use and can be seamlessly integrated into any skincare routine.

Pros

  • Contains 12% niacinamide, which effectively reduces redness and soothes the skin.
  • Includes 2% zinc PCA to help control sebum production and minimize breakouts.
  • Lightweight and non-greasy formula that absorbs quickly into the skin.
  • Free from parabens, gluten, and synthetic fragrances, making it suitable for sensitive skin.
  • Cruelty-free and vegan, with dermatologist-tested formulations.
  • Helps to refine skin texture and reduce the appearance of large pores.
  • Provides hydration and nourishment thanks to the inclusion of hyaluronic acid and vitamin E.

Cons

  • The initial texture can feel slightly sticky before fully absorbing into the skin.
  • Some users might experience a mild tingling sensation upon application, which may not be suitable for very sensitive skin.
  • Results can vary, and consistent use over several weeks is often required to see significant improvements.
  • The packaging, while elegant, does not allow users to see how much product is left, which can be inconvenient.

Neutrogena Hydro Boost+ Niacinamide Serum

Neutrogena Hydro Boost+ Niacinamide Serum

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Neutrogena Hydro Boost + Niacinamide Serum offers an advanced approach to skincare by combining the hydrating power of hyaluronic acid with the complexion-enhancing benefits of niacinamide.

Formulated with 10% niacinamide, this serum helps to reduce redness, improve uneven skin tone, and diminish the appearance of dark marks, leaving your skin looking brighter and more balanced. The addition of hyaluronic acid ensures that your skin remains well-hydrated, plump, and smooth.

This fragrance-free, non-comedogenic, and hypoallergenic formula is suitable for all skin types, including sensitive and acne-prone skin. Incorporate this serum into your daily skincare routine to achieve a clearer, more radiant complexion.

Pros

  • Contains 10% niacinamide, which effectively reduces redness and improves uneven skin tone.
  • Includes hyaluronic acid for deep hydration and plumping of the skin.
  • Lightweight and absorbs quickly without leaving a greasy residue.
  • Fragrance-free, paraben-free, phthalate-free, and dye-free, making it suitable for sensitive skin.
  • Dermatologist-recommended brand with a non-comedogenic and hypoallergenic formula.
  • Helps to refine the look of pores and diminish the appearance of dark marks.
  • Provides a smooth and radiant complexion with consistent use.

Cons

  • The packaging pump can be inconsistent, sometimes dispensing product unevenly.
  • Some users may find the initial texture slightly sticky before it fully absorbs.
  • May cause a mild tingling sensation for very sensitive skin upon first application.
  • Results can take a few weeks to become noticeable, requiring patience and consistent use.

TruSkin Niacinamide (B3) Serum

TruSkin Niacinamide (B3) Serum

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TruSkin Niacinamide Serum offers a comprehensive solution for those looking to improve their skin's texture and tone while reducing redness. Formulated with a blend of potent ingredients such as Niacinamide (Vitamin B3), Hyaluronic Acid, Vitamin E, Aloe Vera, and Avocado Oil, this serum helps to soothe blemishes, minimize pores, and hydrate the skin.

It works effectively to even out skin tone and combat fine lines and wrinkles, making it a versatile addition to any skincare routine. Ideal for all skin types, this dermatologist-tested serum is free from fragrances, parabens, and other harmful chemicals, ensuring a gentle yet powerful treatment for your skin

Pros

  • Contains Niacinamide, which helps to reduce redness and improve skin texture.
  • Hyaluronic Acid delivers intense hydration, keeping the skin plump and moisturized.
  • Vitamin E and Avocado Oil support skin elasticity and moisture retention.
  • Aloe Vera nourishes and soothes the skin, reducing irritation.
  • Formulated for all skin types, making it versatile and inclusive.
  • Fragrance-free and free from parabens, ensuring a gentle formulation.
  • Dermatologist-tested and cruelty-free, supporting ethical skincare practices.
  • Helps to even out skin tone and reduce fine lines and wrinkles.

Cons

  • Initial results may take a few weeks to become noticeable, requiring consistent use.
  • Some users may experience a mild tingling sensation upon first application.
  • The creamy texture might feel slightly heavy for those with very oily skin.
  • Requires a patch test before use to avoid potential irritation.

Redness Prone Skin Serum Niacinamide 10%

Redness Prone Skin Serum Niacinamide 10%

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Real Basic Redness Prone Skin Serum offers an effective solution for those seeking to reduce redness and achieve an even skin tone. Formulated with a powerful 10% Niacinamide, this serum is designed to soothe and diminish inflammation and redness while improving the overall texture of the skin.

Additionally, it contains Kombucha at an active level of 3%, a breakthrough ingredient that helps to brighten, balance, and protect the skin. The serum is further enhanced with natural ingredients like Aloe Vera, which nourishes and soothes the skin, making it suitable for all skin types.

It can be incorporated into your daily skincare regimen both in the morning and evening, ensuring consistent care and noticeable results over time.

Pros

  • Contains 10% Niacinamide, which is highly effective in reducing redness and evening out skin tone.
  • Formulated with Kombucha, a vegan probiotic that brightens, soothes, balances, and protects the skin.
  • Includes Aloe Vera, known for its nourishing and soothing properties.
  • Suitable for all skin types, making it a versatile addition to any skincare routine.
  • Cruelty-free and made in the USA with natural ingredients.
  • Can be used twice daily, fitting seamlessly into both morning and evening skincare routines.
  • Free from parabens and other harmful chemicals, ensuring a gentle formulation.

Cons

  • Some users may find the serum to be slightly sticky after application.
  • The serum may not be effective for all types of redness, particularly those not related to skin dryness.
  • A patch test is recommended before use to avoid potential irritation.

Final Words

Among the top 10 best niacinamide serums, the COSRX Niacinamide 15% Face Serum stands out as the best choice for reducing redness and improving overall skin health. With its high concentration of 15% niacinamide, this serum effectively addresses multiple skin concerns, including redness relief, enlarged pores, and discoloration.

The addition of Zinc PCA helps regulate sebum production and prevent breakouts, making it particularly suitable for oily and acne-prone skin. Its formulation with skin-friendly ingredients and adherence to hypoallergenic and cruelty-free standards further solidifies its top pick position.

Experience the transformative benefits of COSRX Niacinamide 15% Face Serum and achieve calmer, more radiant skin. Incorporate this powerful serum into your skincare routine and see the difference. Order now and take the first step towards healthier, more even-toned skin.

FAQs about Niacinamide Serums

Can niacinamide serums be used with other active ingredients?

Yes, niacinamide serums can often be used with other active ingredients like retinol, vitamin c, caffeine, or salicylic acid.

What percentage of Niacinamide is effective in reducing redness?

Niacinamide concentrations between 2%-5% effectively reduce redness and improve overall skin texture.

How often should Niacinamide serum be applied?

Niacinamide serum is ideal for twice-daily use.

References

  • Gehring W. (2004). Nicotinic acid/niacinamide and the skin. Journal of cosmetic dermatology, 3(2), 88–93. https://doi.org/10.1111/j.1473-2130.2004.00115.x
  • Saurat, J.-H., Halioua, B., Baissac, C., Saint Aroman, M., Taieb, C., & Skayem, C. (2024). Epidemiology of acne and rosacea: A worldwide global study. Journal of the American Academy of Dermatology, 90(5), 1016-1018. https://doi.org/10.1016/j.jaad.2023.12.038
  • Marques, C., Hadjab, F., Porcello, A., Lourenço, K., Scaletta, C., Abdel-Sayed, P., Hirt-Burri, N., Applegate, L. A., & Laurent, A. (2024). Mechanistic Insights into the Multiple Functions of Niacinamide: Therapeutic Implications and Cosmeceutical Applications in Functional Skincare Products. Antioxidants (Basel, Switzerland), 13(4), 425. https://doi.org/10.3390/antiox13040425
  • Draelos, Z. D., Ertel, K., & Berge, C. (2005). Niacinamide-containing facial moisturizer improves skin barrier and benefits subjects with rosacea. Cutis, 76(2), 135–141. Retrieved from https://pubmed.ncbi.nlm.nih.gov/16209160/
  • Viyoch, J., Tengamnuay, I., Phetdee, K., Tuntijarukorn, P., & Waranuch, N. (2010). Effects of trans-4-(aminomethyl) cyclohexanecarboxylic acid/potassium azeloyl diglycinate/niacinamide topical emulsion in Thai adults with melasma: a single-center, randomized, double-blind, controlled study. Current therapeutic research, clinical and experimental, 71(6), 345–359. https://doi.org/10.1016/S0011-393X(10)80001-3
  • Boo Y. C. (2021). Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation. Antioxidants (Basel, Switzerland), 10(8), 1315. https://doi.org/10.3390/antiox10081315