Top 7 Best Folate and B12 Supplements
UpdatedOctober 23, 2024
Folate and B12 are two important vitamins that need to be taken for the proper functioning of the human body. Folate or vitamin B9 is necessary for the creation of red blood cells, as well as DNA and RNA. It also helps to regulate the nervous system effectively. Vitamin B12 on the other hand is useful in the formation of red blood cells, proper functioning of the brain, and also in DNA synthesis.
Though both folate and B12 can be obtained from the normal diet, there might be times when a person may need a supplement to help him/her get the needed amount of the two for the day. This is especially true when taken by pregnant women, vegetarians, or people with some medical conditions. Selecting the right folate and B12 supplement may be a little difficult since there are many types and brands that can be purchased today.
To come up with the top supplements in folate and B12, we spent several hours looking for and comparing different products. In the subsequent sections of this guide, we shall be presenting our most recommended products and giving a comprehensive analysis of each of them.
Top 3 Best Folate and B12 Supplements
Designs for Health Homocysteine Supreme
If you are interested in a high-quality folate supplement that assists with the metabolism of carbohydrates and the breakdown of proteins in the body, Pure Encapsulations B12 Folate is the product to consider. It supports metabolism, nerve function the brain, and digestion.
Pros
- Contains Methylated B vitamins for superior absorption
- Supports brain and cardiovascular health
- Vegetarian-friendly and free from soy, gluten, and GMOs
- Promotes healthy methylation and homocysteine metabolism
Cons
- Requires two capsules daily
- Higher price point compared to basic B vitamins
This supplement is packed with methylated B vitamins, including B6, B12, and folate, ensuring optimal absorption. It also includes L-serine and Trimethylglycine (TMG), known for their role in promoting healthy methylation, which is crucial for managing homocysteine levels. Riboflavin and Pyridoxal-5-Phosphate (P5P) are included to further support these metabolic pathways. Designed for vegetarians, it’s also free from common allergens like soy and gluten.
We’ve noticed a significant difference in how our body handles energy levels and mental clarity after incorporating this into our routine. The combination of B12 and folate, along with TMG, works seamlessly to support both brain function and cardiovascular health. It's particularly beneficial if you're concerned about homocysteine levels, which can impact heart health. The formula is easy to digest, and with just two capsules a day, it fits well into our daily regimen without any hassle. Overall, this supplement delivers excellent results for those looking to support their brain and heart health naturally.
If you are interested in a high-quality folate supplement that assists with the metabolism of carbohydrates and the breakdown of proteins in the body, Pure Encapsulations B12 Folate is the product to consider. It supports metabolism, nerve function the brain, and digestion.
Pros
- The active form of the B12 vitamin, methylcobalamin, supports GI tract and liver health.
- Pure Encapsulations products are free from common allergens, artificial or unnecessary ingredients, and GMOs.
- Folate is essential for fetal neural development, while B12 is an important nutrient for memory and cognitive support.
Cons
- The capsules are unflavored and may have a slightly unpleasant taste.
- The product is slightly more expensive than other similar supplements on the market.
- Some users may experience mild side effects such as headaches or upset stomachs.
In fact, we have been using Pure Encapsulations B12 Folate for about several weeks now, and we noticed some improvements. We are more energetic and our memory and cognitive functions are also enhanced. We also acknowledge that the product does not contain typical allergens or other additives which could be unhealthy to the users diets.
The supplement is convenient to use without any side effects being felt in the body. The capsules themselves are not flavored, which is fine because the capsules are small and easy to swallow. In conclusion, Pure Encapsulations B12 Folate supplement can be recommended for any person in search of a good folate supplement that can have an impact on multiple health aspects.
If you are in the market for a good and high-quality folate and B12 supplement, we strongly suggest Designs for Health Ultra B12-Folate.
Pros
- The NatureFolate blend contains safe, naturally-occurring folates in their active 5-MTHF form.
- The premium B12 in this product comes from equal amounts of adenosylcobalamin and methylcobalamin.
- The product is Non-GMO, Gluten-Free, and Vegetarian-friendly.
Cons
- The product is a bit expensive compared to other folate and B12 supplements.
- Some customers may find the capsules a bit difficult to swallow.
- The product may not work for everyone, as individual results may vary.
We have directly recommended a Designs for Health Ultra B12-Folate supplement and have found it to work well in enhancing methylation and encouraging proper levels of homocysteine to be maintained. It is also recommended for vegetarians and Vegans.
This product contains NatureFolate, carefully formulated, natural folates in their active 5-MTHF form, which is safer than synthetic folate. The premium B12 in this product contains equal concentrations of adenosylcobalamin and methylcobalamin, which are the active forms of B12.
On the matter of quality raw material, Designs for Health adheres to a no-compromises policy. It remains important to note that this product is non-GMO, Gluten-Free, and Vegetarian. More than 50,000 doctors have confirmed that Designs for Health is the physician’s choice among high-quality professional-strength supplements since 1989. Their “Science First” policy ensures that all their products reflect the most cutting-edge scientific research and contain the finest quality ingredients.
Therefore, if you are searching for an efficient and high-quality supplement of folate and B12, we suggest you try Designs for Health Ultra B12-Folate.
Jarrow Formulas Extra Strength Methyl B-12 1000 mcg & Methyl Folate 400 mcg + P-5-P
Jarrow Formulas Extra Strength Methyl B-12 1000 mcg & Methyl Folate 400 mcg + P-5-P
If you need an all-natural, easy-to-swallow, vegan, and gluten-free supplement that helps in enhancing the cellular energy metabolism, brain, nerve, and cardiovascular system, then Jarrow Formulas Extra Strength Methyl B-12 1000 mcg & Methyl Folate 400 mcg + P-5-P might be for you.
Pros
- Unique combination of B Vitamins in easy-to-take, lemon-flavored chewable tablets
- Contains Methyl B12, Methyl Folate, and Pyridoxal-5-Phosphate (P-5-P), the active forms of Vitamins B-12, B9, and B6
- Supports neurologic health, cellular energy metabolism, proper cell division, and the metabolism of proteins and amino acids
Cons
- The taste might not be for everyone
- Some people might prefer a different form of supplement, such as a capsule or liquid
- Results may vary depending on individual health needs and lifestyle factors
For a couple of weeks now, we have been taking Jarrow Formulas Extra Strength Methyl B-12 1000 mcg & Methyl Folate 400 mcg + P-5-P chewable tablets that are easy to take and come with an optimum citrus flavor. We also note that this supplement has active forms of Vitamins B-12, B9, and B6, which means that the human body can easily assimilate them.
We also appreciate that it contributes to neurologic function, cellular energy production, correct DNA synthesis, and protein and amino acids metabolism. In regards to positive changes, it has been observed that there are better energy levels during the day and improved alertness.
That being said though, we can understand that not everyone may like the taste, and there are people who will prefer taking a capsule or even a liquid supplement. It is also important to note that the outcome of any treatment may differ from one person to another depending on his or her health status or behaviors.
All in all, we would suggest Jarrow Formulas Extra Strength Methyl B-12 1000 mcg & Methyl Folate 400 mcg + P-5-P for all those who seek an efficient supplement that positively contributes to the enhancement of the cellular energy metabolism, brain and nerve efficacy, as well as cardiovascular system.
Life Extension BioActive Folate & Vitamin B12 – For Heart, Brain & GI Tract Health
Life Extension BioActive Folate & Vitamin B12 – For Heart, Brain & GI Tract Health
If you’re interested in a supplement that supports cardiovascular, cognitive, and gastrointestinal well-being, then Life Extension’s BioActive Folate & Vitamin B12 is a top-notch solution.
Pros
- We love that this supplement contains the active forms of folate (as 5-MTHF) and vitamin B12 (as methylcobalamin) that are readily absorbed by the body.
- This supplement offers many health benefits, including promoting healthy DNA function, maintaining healthy homocysteine levels for heart health, supporting brain health and cognition, and promoting healthier skin, a healthy digestive tract, and a healthy immune response.
- We appreciate that this supplement is non-GMO, gluten-free, and manufactured in the USA, ensuring that the raw ingredients are of the highest quality.
Cons
- This supplement may not be suitable for people who are allergic to any of the ingredients.
- Some users may find the price of this supplement to be a bit high compared to other similar supplements.
- This supplement may not be suitable for people who are looking for a supplement that contains a higher dosage of folate or vitamin B12.
Life Extension BioActive Folate & Vitamin B12 are two vitamins that are crucial for proper health of an individual. Folate is a vitamin of the B-complex group and is abundant in green leafy vegetables. It converts vitamin B12 into one of the biologically active forms and is involved in an enzymatic process that synthesizes the DNA required for cell division and the formation of new cells. Folate benefits include playing a role in the promotion of healthy DNA synthesis, in maintaining already normal homocysteine blood levels for heart health, and in supporting healthy skin, digestion, and immune functions.
All in all, we unhesitatingly endorse Life Extension BioActive Folate & Vitamin B12 to anyone interested in taking a superior supplement related to cardiovascular, neurological, and gastrointestinal health.
Why Not Natural Vitamin B12 Liquid Plus Folate
Why Not Natural Vitamin B12 Liquid Plus Folate
If you are planning to produce natural energy, enhance your mood, or sharpen your memory, then you should try using Why Not Natural Vitamin B12 Liquid Plus Folate.
Pros
- Achieves natural energy, mood, and memory boost.
- Supports healthy metabolism, immunity, and nervous system functioning.
- Features methylcobalamin and folinic acid, the bioavailable forms of B12 and folate.
Cons
- Tastes bitter and not unflavored as advertised.
- Difficult to quickly determine the dosage.
- May not work for everyone.
We have used Why Not Natural Vitamin B12 Liquid Plus Folate, and it is clear that it works. We seemed more alert during the day and also experienced an improvement in our mood. We also observed that particularly our memory and general body health are enhanced for the better.
The supplement is an organic sublingual Vitamin B12 and folate that can help to control homocysteine levels, the heart and brain functions, metabolism, and GI tract. Folate is essential in the creation of the spinal cord and is valuable for women who may become pregnant.
It is worth mentioning that this product contains methylcobalamin and folinic acid, which are the active forms of B12 and folate, respectively, that the body can easily absorb. It does not have toxic cyanide or synthetic folic acid like other low-quality vitamin supplements.
The graduated/printed dropper enables you to get 2000mcg B12 + 800mcg folate or some other amount that is suitable for an individual. However, the addition of the black liquid and the black markings on the dropper hinder one from estimating the dosage quickly.
All in all, if it is a safe and natural need for an energy/mood and memory boost that you are searching for, then Why Not Natural Vitamin B12 Liquid Plus Folate should not be overlooked.
Vital Nutrients Vitamin B12 and Methyl Folate
Vital Nutrients Vitamin B12 and Methyl Folate
For those people who are interested in obtaining a quality folate and B12 supplement, then you might want to consider the Vital Nutrients Vitamin B12 and Methyl Folate.
Pros
- Supports gastrointestinal health
- Methylated forms of B12 and folate are highly bioavailable
- Contains L-5-MTHF 800mcg, which may reduce the risk of neural tube birth defects
Cons
- Capsules may be difficult to swallow for some
- May not be suitable for those with certain medical conditions
- Somewhat expensive compared to other options
We’ve been using Vital Nutrients Vitamin B12 and Methyl Folate for some weeks now, and the changes in my energy level and general health are positive. This supplement is also unique because it supports the health of the digestive system. There have been fewer digestive complications since using it, which has been a plus for us.
We also like the fact that this supplement absorbs well in the body, and this is due to its bioavailability. These are the methylated forms of B12 and folate; therefore, the body absorbs all the benefits from these doses without wasting any. We also noted that this supplement comes with L-5-MTHF 800mcg and is very relevant for pregnant or intending to get pregnant women.
Having learned from our experience with Vital Nutrients Vitamin B12 and Methyl Folate, we want to admit that the supplement in question may not fit everyone. Some people may have difficulties swallowing the capsules, and people with some underlying health issues should talk to their doctors first before taking this product. However, it is slightly pricier than some of the other products available on the market today.
In conclusion, Vital Nutrients Vitamin B12 and Methyl Folate should be recommended as a perfect product for patients in need of folate and B12 supplement that also contributes to the health of the gastrointestinal tract and the overall health of the patient.
Buying Guide
Form of Supplement
Folate and B12 are available in different formats including capsules, tablets, and gummies. Both forms have their merits and demerits. Capsules and tablets are easy to swallow and can be stored for longer periods, while gummies may be more pleasant to take for those who face challenges when swallowing pills.
Dosage
The amount of folate and B12 present in the supplements also differ from one product to the other. It is necessary to select a product that contains these vitamins at the recommended daily allowance. Just remember to read the label before use to confirm whether the dosage is going to meet your needs or not.
Quality
It is important to note the quality of the supplement being used. Choose products from well-established firms and those that have gone through third-party testing and certification. This helps to confirm that the product has the stated ingredients on the can and does not contain any harmful substance.
Additional Ingredients
Certain folate and B12 supplements may also include other compounds such as other vitamins or minerals. These can be useful but it must be seen that they do not interfere with the medications that you might be undergoing. It should be noted that before using any new supplement, it is advisable to consult your doctor.
Frequently Asked Questions
What are the best brands of B12 supplements to take daily?
Presently, there are different types of efficient supplements of B12 that are available for consumers in the market. Some of the leading brands of vegetarian supplements are Garden of Life, Jarrow Formulas, and Solgar. This is because the quality of a product is determined by the ingredients used in the production and production procedures.
What are the benefits of taking a B12 supplement with methylcobalamin and adenosylcobalamin?
Methylcobalamin and adenosylcobalamin are two forms of B12 that are considered to have high bioavailability. Consuming a supplement that contains both of these forms can be beneficial in maintaining healthy energy metabolism, cognition, and immune system.
What are some vegan-friendly B12 supplements?
Most of the B12 supplements come from animals; however, there are vegan types on the market as well. The best vitamins for vegans are Garden of Life Vitamin Code Raw B12, Deva Vegan B12, and Solgar Sublingual Methylcobalamin.
How can I increase my intake of vitamin B12 and folate through my diet?
Some of the foods rich in B12 are those of animal origin, including meat, fish, and dairy products. People who avoid animal products should opt for fortified plant-based milks, cereals, and nutritional yeast as sources of B12. The rich sources of folate are green vegetables, beans, and grains that are fortified with this vitamin.
What are the differences between sublingual and tablet forms of B12 supplements?
Sublingual B12 is a type of supplement meant to be placed under the tongue where it quickly supplies the body with the vitamin B12 it needs. Cyanocobalamin B12 comes in tablet forms, which must be ingested and the substance is absorbed in the gastrointestinal tract. It is also useful to mention that for people with gastrointestinal pathology the sublingual forms might be more useful.
Is it recommended to take B12 and folate together for optimal health?
B12 and folate are involved in the synthesis of red blood cells and proper functioning of the neurological system. Combining these two nutrients might have extra benefits that were not observed when supplementing with only one of them. Nonetheless, it is crucial to consult a healthcare provider before undertaking any new supplement intake plan.
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