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Top 13 Best Saffron Supplements for Depression

Written by Andrew Le, MD

UpdatedOctober 23, 2024

Depression is a known psychological disorder that cuts across all the demographical divisions of people in the global society. Though there are numerous treatment procedures which have been known to work, some people still prefer to take natural products to treat their illness. One of such supplements which has recently sparked much interest regarding possible antidepressant properties is saffron.

Saffron is an herb that comes from the Crocus sativus plant and it is commonly used as a flavoring agent and coloring. In traditional system of medicine it has been employed since old ages for the cure of various diseases and conditions such as depression. Saffron has many phytochemicals like crocin and safranal that have been postulated to possess mood-regulating effects.

Top 3 Best Saffron Supplements for Depression

  1. Nutricost Saffron Extract 88.5mg, 240 Capsules
  2. Luma Nutrition Saffron Extract Capsules
  3. FORCE FACTOR Perfect Maca

We know how depression affects a person, and that is why we have provided a list of the best saffron supplements for depression. To make your shopping on Amazon simpler, our team has investigated and reviewed efficient saffron supplements. Parameters that were evaluated include the purity of the saffron extract, the active dose, and feedback received from customers. Keep reading to learn more about our favorite saffron supplement for depression


Nutricost Saffron Extract 88.5mg, 240 Capsules

Editor's Choice

Nutricost Saffron Extract 88.5mg, 240 Capsules

Our experience with Nutricost Saffron Extract revealed mood enhancement and anxiety reduction. Vegetarian, gluten, soy, and GMO-free—a blessing for dietary restrictions. While results varied among users and side effects were possible, patience and medical advice are key. Seeking a natural depression aid? Worth a shot!

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If you want to take a natural supplement which can be useful in depression, then Nutricost Saffron Extract could be of your interest.

Pros

  • Contains 88.5mg of saffron per serving
  • 240 vegetarian capsules per bottle for 240 servings (just 1 capsule per serving)
  • Vegetarian, gluten-free, soy-free, and non-GMO

Cons

  • Some users reported no noticeable effects
  • May take a few weeks to see results
  • Some users may experience mild side effects like dry mouth or dizziness

We decided to use Nutricost Saffron Extract for a few weeks and noted that it made a positive impact on our mood and lessened the level of anxiety. It is also vegetarian, gluten-free, soy-free, and non-GMO, so it is suitable for people with special needs.

There are some clients who stated that they didn’t see any changes, but it should be noted that it may take up to two weeks for the treatment to have an effect. However, some of the people may experience side effects such as dry mouth, dizziness and others hence consulting a doctor before taking any supplement is advisable.

In conclusion if you are seeking a natural supplement to use in the treatment of depression then Nutricost Saffron Extract could be of benefit to you.


Luma Nutrition Saffron Extract Capsules

Luma Nutrition Saffron Extract Capsules

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Luma Nutrition Saffron Extract Capsules can be a good supplement for mood support and for the health of the eyes.

Pros

  • Powerful supplement with multiple benefits
  • Made by a trusted brand with a satisfaction guarantee
  • Easy-to-swallow veggie capsules

Cons

  • May not work for everyone
  • Some users report no noticeable benefits
  • May take time to see results

I have been taking the Luma Nutrition Saffron Extract Capsules for a few weeks now and I feel that the product has had a real impact on my mood. They come in capsule form, which can be easily swallowed and does not cause any aftertaste.

Another advantage of this supplement is that it enhances the mood. Saffron extract was found to increase the serotonin level which has mood improving characteristics. Also, it is noteworthy that saffron extract can also be helpful to anyone who seeks to enhance his or her eyesight.

We note that Luma Nutrition is an established brand that is committed to the quality of its goods. They guarantee full refund or replacement in case the customers are not happy with products they have bought. You just need to talk to them and they will sort you out.

Still, we have to acknowledge that this supplements may have a negative effect on some people even if it had a positive effect on us. Some users have said they did not notice any positive changes, it may take some time before the outcome is observed. All the same, in our view, Luma Nutrition Saffron Extract Capsules deserve a place on the list of natural supplements to boost mood and eye health.


FORCE FACTOR Perfect Maca

FORCE FACTOR Perfect Maca

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We recently tried the FORCE FACTOR Perfect Maca Supplement, and it's clear why it's considered one of the best saffron supplements for depression. This supplement combines the power of Maca root, DIM, and saffron to offer a holistic approach to mood and energy support. Available in a dark cherry flavor, these 60 soft chews are designed to be both effective and enjoyable.

Pros

  • The blend of Yellow and Black Maca provides a balanced approach to enhancing energy and mood.
  • Added vitamins, minerals, and antioxidants contribute to overall wellness.
  • Saffron is known for its potential to support mood regulation, making this supplement ideal for those struggling with depression.
  • The dark cherry flavor makes taking the supplement a pleasant experience.

Cons

  • The soft chews might not be suitable for those with dietary restrictions or preferences against sweeteners.
  • As with any supplement, individual results may vary

FORCE FACTOR Perfect Maca combines Yellow and Black Maca root, DIM (Diindolylmethane), and saffron to create a powerful supplement that supports both energy levels and mood. Each chew contains a blend of essential vitamins and minerals, along with antioxidants to enhance overall health. The dark cherry flavor adds a touch of sweetness, making these soft chews easy to incorporate into your daily routine.

FORCE FACTOR Perfect Maca lives up to its promises. We noticed a boost in energy levels and a positive shift in mood after consistent use. The combination of Maca root and saffron seems to work well, providing a noticeable improvement in overall well-being. The chews are convenient and enjoyable, making them a practical choice for those seeking a natural mood and energy boost.


Double Wood Supplements Saffron Extract Capsules

Double Wood Supplements Saffron Extract Capsules

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For people who are seeking for a supplement that can naturally help them with their mood and appetite issues, we fully endorse the Double Wood Supplements Saffron Extract Capsules.

Pros

  • Supports healthy appetite control
  • Supports optimal eye health
  • May support optimal mood
  • Vegan, Non-GMO, Gluten-Free
  • Manufactured and tested in the USA

Cons

  • May not work for everyone
  • May take time to see results
  • May interact with certain medications

This product comes with a high concentration of saffron extract per capsule which is known to control hunger and in turn reduce meal intake. Further, it should also be mentioned that saffron extract contains a high concentration of carotenoids which are essential for proper functioning of eyes. We also liked the fact that the capsules are vegan and non GMO, they do not contain gluten and are made and tested in USA for microbes and heavy metals.

However, one has to understand two things; the saffron extract may not have the same effect on everyone and may take sometime to show results. They also advise that one should contact a doctor before using this supplement if they are taking other medicines.

In sum, we think that if you want to improve your mood, appetite control, and other similar issues, then Double Wood Supplements Saffron Extract Capsules can be helpful for you.


Flamingo Supplements Saffron Extract Gummies

Flamingo Supplements Saffron Extract Gummies

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Flamingo Supplements Saffron Extract Gummies have become one of our top choices for mood support and managing symptoms of depression.

Pros

  • Sugar-free and easy to consume.
  • Combines saffron with mood-enhancing ingredients like GABA and Saint John’s Wort.
  • No artificial flavors or additives.

Cons

  • Limited supply in each bottle (only 60 gummies).
  • May take time to see noticeable effects.
  • Some users might find the flavor slightly bitter.

Flamingo Supplements Saffron Extract Gummies contain 88mg of saffron extract per serving, which is known for supporting emotional health and focus. Enhanced with GABA, a natural relaxant, Saint John’s Wort, which is often used for depression, and Passion Flower to reduce anxiety, this formula provides comprehensive mental support. These gummies are sugar-free, which makes them ideal for health-conscious individuals or those managing blood sugar levels. Additionally, they’re free from artificial ingredients, making them a clean option for mood management.

We noticed a significant improvement in overall mood and mental clarity after consistent use. The combination of saffron and the other ingredients worked well to reduce stress and anxiety, especially on tough days. Although the flavor may not appeal to everyone, the benefits far outweigh this minor drawback. With regular use, it can be a great, natural supplement for managing low moods or stress.


NUTRAHARMONY Natural Saffron Supplements

NUTRAHARMONY Natural Saffron Supplements

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In our search for the best saffron supplement for mood support, we came across NUTRAHARMONY Natural Saffron Supplements. These capsules offer a potent 88.5 mg of pure saffron extract, providing a natural solution for enhancing mood, focus, vision, and energy. Made in the USA, these Non-GMO, vegan pills come in a convenient 90-capsule bottle, offering a 3-month supply for both men and women.

Pros

  • Potent 88.5 mg saffron extract per capsule
  • Supports mood, focus, vision, and energy
  • Non-GMO and vegan
  • 3-month supply in one bottle

Cons

  • Capsules might be large for some to swallow

NUTRAHARMONY Natural Saffron Supplements boast a variety of impressive features. Each capsule contains a potent 88.5 mg dose of pure saffron extract, designed to support mood, focus, vision, and energy levels. This supplement is crafted in the USA, ensuring high-quality production standards. The capsules are Non-GMO and vegan, catering to a wide range of dietary needs. Additionally, the 90-capsule bottle provides a 3-month supply, making it a cost-effective choice for long-term use.

We've noticed significant improvements in our mood and focus after consistently taking these supplements for a few weeks. The boost in energy is subtle but noticeable, helping us stay more alert throughout the day. Our vision also seems sharper, adding to the overall benefits. While the capsules are a bit large, they are manageable with water. Despite being on the pricier side, the quality and effectiveness of NUTRAHARMONY Natural Saffron Supplements make them a worthwhile investment for those seeking a natural approach to mood and energy support.


OLLY Hello Happy Gummy Worms

OLLY Hello Happy Gummy Worms

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We’ve been exploring mood-enhancing supplements, and OLLY Hello Happy Gummy Worms have quickly become our favorite for mood support. With their unique blend of Vitamin D and saffron, these gummies are designed to boost mood and promote emotional well-being.

Pros

  • Delicious Taste
  • The combination of saffron and Vitamin D is known for its mood-boosting properties.
  • These gummies are a hassle-free alternative to traditional supplements

Cons

  • Each serving contains a fair amount of sugar, which might be a concern for those monitoring their sugar intake.
  • While effective for many, individual results can vary

OLLY Hello Happy Gummy Worms stand out with their thoughtful formulation. Each gummy is packed with saffron, a well-regarded herb for mood support, combined with Vitamin D to enhance overall well-being. The gummies are adult-friendly, easy to chew, and come in a tropical zing flavor that makes them a treat rather than a chore. Plus, the 60-count bottle ensures a one-month supply, making it a practical choice for daily use.

OLLY Hello Happy Gummy Worms deliver on their promise of mood support. The blend of saffron and Vitamin D has proven effective in helping us manage stress and elevate our mood. The gummies are a pleasant addition to our wellness routine, offering both taste and tangible benefits.


Clean Nutraceuticals Saffron Supplements

Clean Nutraceuticals Saffron Supplements

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We recently tried Clean Nutraceuticals Saffron Supplements with Ashwagandha 8000mg, and we believe these are the best saffron supplements for depression. Combining potent ingredients like L-Theanine, Ginkgo Biloba, St. John's Wort, Rhodiola Rosea, and 5-HTP, this supplement promises comprehensive mood support and stress relief.

Pros

  • High potency blend of mood-enhancing ingredients
  • Includes natural adaptogens for stress relief
  • Non-GMO

Cons

  • Large capsule size might be challenging for some
  • Requires consistent use for best results
  • Some ingredients may interact with medications

Clean Nutraceuticals Saffron Supplements boast a powerful blend of ingredients. With 8000mg of Ashwagandha, known for its stress-relieving properties, and 200mg of L-Theanine for calming effects, these capsules offer a balanced approach to mood support. The 6000mg of Ginkgo Biloba enhances cognitive function, while St. John's Wort at 6000mg and Rhodiola Rosea at 3000mg work together to alleviate depressive symptoms and boost overall mental health. Additionally, the inclusion of 500mg of 5-HTP aids in serotonin production, further supporting mood stabilization.

In our experience, Clean Nutraceuticals Saffron Supplements effectively elevate mood and reduce stress. After consistent use over a few weeks, we noticed a significant improvement in our overall emotional well-being. The combination of Ashwagandha and L-Theanine helped us feel calmer and more centered throughout the day. Ginkgo Biloba and Rhodiola Rosea provided an extra boost in mental clarity and focus, while St. John's Wort and 5-HTP contributed to a noticeable reduction in depressive symptoms. However, due to the high potency of the ingredients, it's essential to monitor for any interactions with other medications.


Aurite Saffron Supplement

Aurite Saffron Supplement

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For those seeking a safe and herbal solution for their mental health and brain function, Aurite Saffron Supplement could be your perfect match.

Pros

  • With regular use, it can help reduce stress and promote a positive mood.
  • Made with a vegetarian-friendly formula that is free from GMOs, gluten, and soy.
  • Each bottle contains 60 capsules, providing a convenient and long-lasting supply.

Cons

  • Some users reported feeling tired after taking the supplement.
  • The effects may not be noticeable immediately.
  • The price point may be higher than other saffron supplements on the market.

Aurite Saffron Supplement has proven to be useful in dealing with stress, and generally, enhance the calmness one feels in a given day. We like that it is formulated with pure saffron extract and there are no other chemicals involved in its production. This is also good for us given that we are vegetarians and hence the vegetarian-friendly formula.

It is also important to note that the effects may not be realised in the short-term. It may take a few days or even weeks to see the improvement in your mood and mental abilities. Further, some users have complained of dizziness and sometimes getting tired easily after taking the supplement, and this is something one should look out for.

All in all, we would encourage everyone interested in natural mood enhancement and cognitive performance booster to give Aurite Saffron Supplement a shot.


UpNourish Joyful Saffron and Ashwagandha

UpNourish Joyful Saffron and Ashwagandha

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If you are wondering about the herbal remedies for stress and mood support, UpNourish Joyful Saffron and Ashwagandha could be a good choice.

Pros

  • The combination of clinically proven SENSORIL ashwagandha organic extract, AFFRON saffron extract, gut-brain axis probiotics, L-Theanine, adaptogens Rhodiola Rosea and Siberian Ginseng provides a comprehensive approach to stress relief and mood enhancement.
  • AFFRON saffron extract has been shown in clinical studies to improve rest quality and reduce the number of awakenings during the night.
  • The 180-day money-back guarantee provides peace of mind for those who are not satisfied with the product.

Cons

  • The product may not be suitable for those who are allergic to any of the ingredients.
  • The effects may vary from person to person and may take some time to become noticeable.
  • The product is relatively expensive compared to other saffron supplements on the market.

For several weeks now we have been taking UpNourish Joyful Saffron and Ashwagandha and already feel the difference in our mood and energy. The blend of adaptogenic herbs, probiotics, and saffron extract is well combined in the formula to enhance the relaxation process while at the same time providing energy and concentration boost.

The capsules are small and are easily ingested, the product appears to be of good quality. We also like that the product is vegan and has no artificial colors, flavors, and preservatives.

All in all, we would encourage anyone who is in search of natural means of managing stress or even uplifting their moods to consider using UpNourish Joyful Saffron and Ashwagandha. It does not suit everyone but the 180 days’ money back guarantee ensures that the consumer is safe and can try the product and see if it works for him/her or not.


Mother Nutrient Saffron Extract Supplements

Mother Nutrient Saffron Extract Supplements

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If you are interested in natural products that may work against depression, we suggest that you try the Mother Nutrient Saffron Extract Supplements.

Pros

  • The saffron extract is of premium quality, resulting in a sought-after reddish orange color in every capsule.
  • The value is unbeatable, with 210 vegetarian capsules per bottle, which equates to a seven-month supply.
  • The capsules are easy to take, with just one veggie capsule per day to get an 88.5 mg dose of Crocus Sativus.

Cons

  • It may take some time to see the effects, as with any natural supplement.
  • The effects may not be as strong as with prescription medication.
  • The capsules may not work for everyone.

In the course of the research we noted that the Mother Nutrient Saffron Extract Supplements had an affirmative impact on our mood and specifically the symptoms associated with depression. The capsules were convenient to swallow and did not come with any unwanted additives or artificial ingredients. It was good to have confirmation that the saffron extract was of good quality to make sure we were provided with the best quality.

Though, it may take a while to experience the changes, our findings were positive; if taken regularly, the supplements helped enhance our health. However, the effects could be less pronounced than those of prescription medicine and, in some cases, the capsules may not produce the intended results.

In general, it is safe to say that the Mother Nutrient Saffron Extract Supplements are an effective natural solution for people experiencing symptoms of depression.


Pure Micronutrients Saffron Supplements

Pure Micronutrients Saffron Supplements

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We highly recommend this product to anyone who is searching for natural way to elevate their mood through supplementing their diet.

Pros

  • Boosts energy, attitude, and mood
  • Supports metabolism and heart health
  • Promotes optimal eye health and macular degeneration

Cons

  • May not work for everyone
  • Some users may experience mild side effects
  • May take some time to see noticeable results

We have ourselves used the Pure Micronutrients Saffron Supplements and have come to have better results. Also, this supplement has antioxidant properties and replenishes dopamine which plays an important role in protecting brain cells from the damaging effects of oxidative stress. There is generally high energy and elevated spirits in the course of the day.

Besides managing mood disorders, this supplement has other benefits of maintaining a healthy metabolism besides heart issues. Saffron has also proved to have high antioxidant compounds, which in turn assist in shaping up the immune system by fighting free radicals. We have also observed a great improvement especially in our eyes after taking this supplement.

This product may not be effective for every user and certain individuals may have mild side effects but since this is a natural supplement, it can be considered as a worthy trial for those who wish to strengthen their immune system. The effects may be noticed after a few weeks and sometimes month; however, the results are exquisite.

In conclusion, Pure Micronutrients Saffron Supplements can be recommended for those willing to improve their mood and overall well-being.


Youtheory Saffron Advanced with Rhodiola, 60 Count

Youtheory Saffron Advanced with Rhodiola, 60 Count

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For people who would like to improve their mood and cognitive functioning, we highly recommend Youtheory Saffron Advanced with Rhodiola.

Pros

  • Youtheory Saffron Advanced with Rhodiola combines three powerful botanicals to help boost mood, reduce stress, and improve mental performance.
  • It is vegan, dairy-free, soy-free, and contains no gluten ingredients.
  • This product is third-party tested and manufactured in the USA.

Cons

  • Some users have reported experiencing hallucinations when taking two capsules.
  • The bottle is large and appears to be only about 1/4 full.
  • It may take time for some of the effects to build up.

During our research, Youtheory Saffron Advanced with Rhodiola has been helpful for enhancing the mood and cognitive functions. Saffron, ashwagandha, and rhodiola together blend into a natural nootropic that sustains energy all day long.

We like that this product is vegan, and it does not contain dairy or soy, which are allergens to many people. Moreover, it is third-party tested, and the product is made in the USA, which makes me trust this supplement.

What one should not forget is that there are cases where people have had hallucinations after taking two capsules. The recommended dosage is one capsule; however, depending on the severity of the condition, the dosage can be doubled.

In conclusion, Youtheory Saffron Advanced with Rhodiola is beneficial for anyone who wants to have a natural method to improve his or her mood and cognitive function.

Buying Guide

When it comes to the selection of the best saffron supplement that can effectively work on depression, it is important that you consider some important factors.

Quality

Saffron quality is not consistent and this makes it crucial that one chooses the right supplement to use that contains good quality saffron. When searching for these supplements, try to find one that contains saffron that has been standardized for particular levels of crocin and safranal. This can help in establishing that the dose you are taking is consistent and has the desired effectiveness.

Dosage

Saffron dosage can also differ between brands and forms of the product, therefore it is crucial to select the supplement that delivers the correct amount. The saffron dosage commonly used in the treatment of depression is approximately thirty milligrams daily. It is important to note that the supplement should have this amount on its label.

Additional Ingredients

It should also be noted that some saffron supplements may come with special additives that can further complement its use. For instance, some supplements may include other natural substances that can affect your mood, including ashwagandha or rhodiola. Some of them may contain vitamin or minerals that help the body to be strong and healthy.

Price

The cost of saffron supplements can also differ and therefore it is important to identify a supplement that fits a certain budget. However, one also needs to keep in mind the reality that lower costing supplements may not be as potent or of equal quality to the more costly ones. You should therefore always take your time and ensure that the supplement that you are going to use is one that is worth your money.

In conclusion, while selecting the saffron supplement for depression, one must ensure that the supplement has quality saffron, appropriate dosage, might contain other components and affordable prices. With these factors in mind, selecting a supplement that would be safe, effective in contributing to an improvement of mood and overall well-being is achievable.

Frequently Asked Questions

What are the benefits of saffron supplements for depression?

Antioxidants found in saffron enhance the mood and reduce common signs of depression . These drugs operate on the system of serotonin in the brain, which is a mood stabilizer.

What are the top-rated saffron supplement brands for depression?

The best saffron supplement brands for the depression are Nature’s Bounty, Life Extension, and Puritan’s Pride. These brands are well known for its good quality supplements and its effectiveness in the treatment of depression.

What is the recommended form of saffron supplement for depression?

For depression, the suggested type of saffron supplement is known as a standardized extract. This type of supplement comes in packages that has a particular quantity of saffron extract thus being able to offer the appropriate amount of the active ingredients.

Are there any side effects of saffron supplements for depression?

Saffron supplements are recognized to be safe and cause little, if any, side effects. However, the common side effects may include nausea, dizziness, or dry mouth. One should consult with the doctor before taking any new supplement particularly when the individual has other medication or any health condition.

Can saffron supplements help improve mood and reduce symptoms of depression?

Yes, research has indicated that saffron supplements have an effect on mood and alleviation of depression symptoms. It is indicated that they act by raising the levels of serotonin in the brain which is a chemical that is associated with moods.

How do saffron supplements compare to other natural remedies for depression?

Saffron supplements are among the several natural products that may help when it comes to managing depression. Other natural interventions include St John’s Wort, Omega Three fatty acids, and exercise. Before starting with new supplements or beginning a new regimen for depression it is advisable that you consult with your physician.

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