Read below about pain in one thigh, including causes and common questions. Or get a personalized analysis of your pain in one thigh from our A.I. health assistant. At Buoy, we build tools that help you know what’s wrong right now and how to get the right care.

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10 Potential Pain in One Thigh Causes

Disclaimer: The article does not replace an evaluation by a physician. Information on this page is provided as an information resource only, and is not to be used or relied on for any diagnostic or treatment purposes.

  1. 1.Femoral Stress Fracture

    A femoral stress fracture is a small crack in the thigh bone (femur). These fractures are most often a result of overuse and are commonly seen with an increase in activity. Stress fractures of the thigh bone are much less common than those of the shin bone (tibia), but nonetheless do occur in high-risk groups such as athletes and military recruits.

    12 weeks is the usual duration of treatment. Stress fractures usually heal on their own.

    Rarity:
    Common
    Top Symptoms:
    dull, achy hip pain, pain in one thigh, thigh pain, spontaneous hip pain
    Urgency:
    Primary care doctor
  2. 2.Thigh Bruise

    A bruise is the damage of the blood vessels that return blood to the heart (the capillaries and veins), which causes pooling of the blood. This explains the blue/purple color of most bruises.

    Bruises will begin to heal over the course of a week

    Rarity:
    Rare
    Top Symptoms:
    pain in one thigh, upper leg injury, thigh pain from an injury, thigh bruise, swelling of one thigh
    Symptoms that always occur with thigh bruise:
    upper leg injury, thigh pain from an injury
    Urgency:
    Self-treatment
  3. 3.Thigh Nerve Issue (Meralgia Paresthetica)

    Meralgia paresthetica is a nerve condition that causes an area of skin over the upper outer thigh to feel numb, tingly, or painful. This is caused by compression of a nerve known as the lateral cutaneous nerve of the thigh as it passes underneath a tough fibrous ligament known as the inguinal ligament.

    Pain and pins-and-needles feeling resolves with time. Sometimes numbness and altered sensation remains for life.

    Rarity:
    Rare
    Top Symptoms:
    pain in the outside of the hip, pain in one thigh, thigh numbness, tingling upper leg, hip numbness
    Symptoms that never occur with thigh nerve issue (meralgia paresthetica):
    new headache, swollen hip, swollen hips, swelling of one hip, leg swelling, weakness of both legs, leg weakness, leaking urine
    Urgency:
    Primary care doctor
  4. 4.Deep Vein Thrombosis

    Deep vein thrombosis (DVT) is a blood clot that forms in a vein deep in the body. Most deep vein clots occur in the lower leg or thigh.

    Curable with medication or surgery but may recur.

    Rarity:
    Uncommon
    Top Symptoms:
    fever, thigh pain, upper leg swelling, calf pain, butt pain
    Urgency:
    Hospital emergency room
  5. 5.Femoral Shaft Fracture

    A femoral shaft fracture is a break anywhere along the long, straight part of the femur (thighbone) known as the shaft. Since the femur is the longest, strongest bone in the body, it is fairly difficult to break it (car crashes account for the most femur fractures).

    4 to 6 months after surgery

    Rarity:
    Rare
    Top Symptoms:
    constant upper leg pain, abnormally high heartrate, swollen thigh, thigh pain, severe thigh pain
    Symptoms that always occur with femoral shaft fracture:
    inability to bear weight immediately after injury, thigh pain, severe thigh pain, pain when touching the thigh, swollen thigh, constant upper leg pain
    Urgency:
    Emergency medical service

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  6. 6.Hip Dislocation

    A slipped capital femoral epiphysis is a separation of the ball of the hip joint from the thigh bone (femur) at the upper growing end (growth plate) of the bone.

    With treatment and after recovery in the hospital, no long-term effects.

    Rarity:
    Rare
    Top Symptoms:
    hip pain, moderate hip pain, dull, achy hip pain, thigh pain, groin pain
    Symptoms that always occur with hip dislocation:
    hip pain
    Urgency:
    Hospital emergency room
  7. 7.Osteoid Osteoma

    An osteoid osteoma is a benign (non-cancerous) tumor that usually develops in the long bones of the legs. The thigh bone (femur) is affected most commonly, although the bones of the hand or the spine can have occasional involvement. This condition is most often found in young people.

    Good prognosis, 90% chance that the condition will not come back. A short recovery time after surgery is expected.

    Rarity:
    Rare
    Top Symptoms:
    lower back pain, upper back pain, spontaneous back pain, back pain that shoots to the butt, severe back pain
    Symptoms that never occur with osteoid osteoma:
    hip pain, bilateral leg swelling, weakness in both arms, weakness of both legs
    Urgency:
    Primary care doctor
  8. 8.Hip Bone Damage (Osteonecrosis)

    Osteonecrosis of the hip is painful, progressive damage of the hip joint caused by a loss of blood flow.

    4 years

    Rarity:
    Rare
    Top Symptoms:
    severe or worsening pain in the hip or groin area, thigh pain, deep, throbbing hip pain, limping, pain in one knee
    Symptoms that always occur with hip bone damage (osteonecrosis):
    severe or worsening pain in the hip or groin area
    Urgency:
    Hospital emergency room
  9. 9.Giant Cell Tumor

    A giant cell tumor (GCT) is a rare benign (non-cancerous) growth that generally occurs in adults between the ages of 20 to 40 years. Most of these tumors appear in the tips of long bones next to joints. GCTs appear on their own for no specific cause. The first symptom that they usually cause is pain.

    Full bone healing after surgery may take up to 6 weeks.

    Rarity:
    Rare
    Top Symptoms:
    pain in one knee, spontaneous bone pain, wrist pain, pain in one thigh, spontaneous hip pain
    Symptoms that always occur with giant cell tumor:
    spontaneous bone pain
    Urgency:
    Primary care doctor
  10. 10.Fibrosarcoma

    The connective tissue found at the ends of bones of the arm or legs can change significantly with aging. Some of these changes can become a serious health risk.

    Prognosis is highly variable and a consultation from a specialist may be required to determine the outlook.

    Rarity:
    Rare
    Top Symptoms:
    neck bump, pain in one knee, abdominal bump, hard palpable mass, spontaneous bone pain
    Urgency:
    Primary care doctor

Questions Your Doctor May Ask About Pain in One Thigh

  • Q.Do your symptoms get worse when you exercise?
  • Q.Do you run for exercise or sport?
  • Q.Which of the following describes your physical fitness:
  • Q.What is your body mass?

If you've answered yes to one or more of these questions, try our pain in one thigh symptom checker to find out more.

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Pain in One Thigh Symptom Checker Statistics

  • People who have experienced pain in one thigh have also experienced:

    • 14% Lower Back Pain
    • 6% Pain in One Hip
    • 2% Deep, Throbbing Hip Pain
  • People who have experienced pain in one thigh had symptoms persist for:

    • 33% Over a Month
    • 26% Less Than a Week
    • 22% Less Than a Day
  • People who have experienced pain in one thigh were most often matched with:

    • 42% Femoral Stress Fracture
    • 4% Thigh Nerve Issue (Meralgia Paresthetica)
    • 2% Thigh Bruise
  • Source: Aggregated and anonymized results from visits to the Buoy AI health assistant (check it out by clicking on “Take Quiz”).

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