Read below about pain in one thigh, including causes and common questions. Or get a personalized analysis of your pain in one thigh from our A.I. health assistant. At Buoy, we build tools that help you know what’s wrong right now and how to get the right care.

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A.I. Health Assistant Causes for Pain in One Thigh

The list below shows results from the use of our A.I. Health Assistant by Buoy users who experienced pain in one thigh. This list does not constitute medical advice.

  1. 1.Femoral Stress Fracture

    A femoral stress fracture is a small crack in the thigh bone (femur). These fractures are most often a result of overuse and are commonly seen with an increase in activity. Stress fractures of the thigh bone are much less common than those of the shin bone (tibia), but nonetheless do occur in high-risk groups such as athletes and military recruits.

    12 weeks is the usual duration of treatment. Stress fractures usually heal on their own.

    Rarity:
    Common
    Top Symptoms:
    dull, achy hip pain, pain in one thigh, thigh pain, spontaneous hip pain
    Urgency:
    Primary care doctor
  2. 2.Greater Trochanteric Pain Syndrome

    Greater trochanteric pain syndrome is a common cause of hip pain caused by damage to the tendons and/or bursa (fluid-filled sac near a joint) at the outside point of the hip known as the greater trochanter.

    Weeks to years

    Rarity:
    Uncommon
    Top Symptoms:
    lower back pain, pain in the outside of the hip, moderate hip pain, groin pain, limping
    Symptoms that always occur with greater trochanteric pain syndrome:
    pain in the outside of the hip
    Urgency:
    Primary care doctor
  3. 3.Repetitive Strain Injury of the Quadriceps

    Repetitive strain injury of the upper leg is caused by consistent repetitive use.

    Resolves with rest

    Rarity:
    Uncommon
    Top Symptoms:
    upper leg numbness, thigh weakness, thigh pain from overuse
    Symptoms that always occur with repetitive strain injury of the quadriceps:
    thigh pain from overuse
    Symptoms that never occur with repetitive strain injury of the quadriceps:
    upper leg injury, severe upper leg pain
    Urgency:
    Self-treatment
  4. 4.Deep Vein Thrombosis

    Deep vein thrombosis (DVT) is a blood clot that forms in a vein deep in the body. Most deep vein clots occur in the lower leg or thigh.

    Curable with medication or surgery but may recur.

    Rarity:
    Uncommon
    Top Symptoms:
    fever, thigh pain, upper leg swelling, calf pain, butt pain
    Urgency:
    Hospital emergency room

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  5. 5.Spinal Stenosis

    The spine, or backbone, protects the spinal cord and allows people to stand and bend. Spinal stenosis causes narrowing in the spine. The narrowing puts pressure on nerves and the spinal cord and can cause pain.

    Indefinite

    Rarity:
    Common
    Top Symptoms:
    lower back pain, back pain that shoots down the leg, back pain that shoots to the butt, difficulty walking, thigh pain
    Urgency:
    Primary care doctor
  6. 6.Thigh Nerve Issue (Meralgia Paresthetica)

    Meralgia paresthetica is a nerve condition that causes an area of skin over the upper outer thigh to feel numb, tingly, or painful. This is caused by compression of a nerve known as the lateral cutaneous nerve of the thigh as it passes underneath a tough fibrous ligament known as the inguinal ligament.

    Pain and pins-and-needles feeling resolves with time. Sometimes numbness and altered sensation remains for life.

    Rarity:
    Rare
    Top Symptoms:
    pain in the outside of the hip, pain in one thigh, thigh numbness, tingling upper leg, hip numbness
    Symptoms that never occur with thigh nerve issue (meralgia paresthetica):
    new headache, swollen hip, swollen hips, swelling of one hip, leg swelling, weakness of both legs, leg weakness, leaking urine
    Urgency:
    Primary care doctor
  7. 7.Compartment Syndrome

    Compartment syndrome is a serious condition that involves increased pressure in a muscle compartment. It can lead to muscle and nerve damage and problems with blood flow.

    Prognosis is highly variable after surgery and depends on how rapidly you are treated.

    Rarity:
    Rare
    Top Symptoms:
    arm numbness, hand numbness, foot numbness, pain in one leg, thigh numbness
    Urgency:
    Hospital emergency room
  8. 8.Pulmonary Embolism

    A pulmonary embolism is a sudden blockage in an artery in the lungs. It is a serious condition that can cause permanent damage to the affected lung, low oxygen levels in your blood, or damage to other organs in your body from not getting enough oxygen.

    A pulmonary embolism is life-threatening. Recovery depends on treatment.

    Rarity:
    Uncommon
    Top Symptoms:
    shortness of breath, cough, rib pain that gets worse when breathing, coughing, sneezing, or laughing, fever, wheezing
    Urgency:
    Emergency medical service
  9. 9.Peripheral Arterial Disease (Pad)

    Peripheral artery disease (PAD) occurs when the big blood vessels, called arteries, become too narrow due to clumps of fat (called plaques) building up inside the walls. If arteries become too narrow, not enough oxygen and nutrients are delivered to the muscles, skin, and organs. The arteries in the legs are often affected first, as they are the furthest from the heart.At first, PAD has no symptoms. As it gets worse, leg pain is likely to develop, leading to cramps in the calf, thigh, foot, or buttock upon exercise. PAD can also increase the risk of a blood clot if a piece of plaque detaches, leading to serious complications such as a heart attack or stroke.Peripheral artery disease is much more common in smokers and in people with diabetes. High blood pressure, high cholesterol, being overweight, and not getting much exercise also can put one at higher risk.

    The prognosis of this disease is highly variable and depends heavily on habits, medical history, and genetics. Peripheral artery disease is a chronic non-life threatening condition. Managing the disease, however, is very important in reducing the risk for stroke and heart attacks, so make sure to follow-up with a physician.

    Rarity:
    Common
    Top Symptoms:
    leg numbness, spontaneous foot pain, decreased exercise tolerance, cold feet, thigh pain
    Symptoms that never occur with peripheral arterial disease (pad):
    calf pain from an injury, thigh pain from an injury
    Urgency:
    Primary care doctor

Questions Your Doctor May Ask About Pain in One Thigh

  • Q.Do your symptoms get worse when you exercise?
  • Q.Do you run for exercise or sport?
  • Q.Have someone hold your leg that is hurting. Let your leg relax as the other person rotates the leg toward the middle. Does this hurt?
  • Q.Stand only on the affected leg. Now hop up and down ten times. Does this cause pain? (This is known as the hop test.)

If you've answered yes to one or more of these questions, try our pain in one thigh symptom checker to find out more.

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Pain in One Thigh Symptom Checker Statistics

  • People who have experienced pain in one thigh have also experienced:

    • 14% Lower Back Pain
    • 6% Pain in One Hip
    • 2% Deep, Throbbing Hip Pain
  • People who have experienced pain in one thigh had symptoms persist for:

    • 32% Over a Month
    • 26% Less Than a Week
    • 22% Less Than a Day
  • People who have experienced pain in one thigh were most often matched with:

    • 50% Femoral Stress Fracture
    • 37% Greater Trochanteric Pain Syndrome
    • 12% Repetitive Strain Injury of the Quadriceps
  • Source: Aggregated and anonymized results from visits to the Buoy AI health assistant (check it out by clicking on “Take Quiz”).

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