Spontaneous Bone Pain Symptoms, Causes & Common Questions

Understand your spontaneous bone pain symptoms, including 7 causes and common questions.

This symptom can also be referred to as: bone hurts for no reason

  1. 7 Possible Spontaneous Bone Pain Causes
  2. Real-Life Stories
  3. Questions Your Doctor May Ask
  4. Statistics
  5. Related Articles

7 Possible Spontaneous Bone Pain Causes

The list below shows results from the use of our quiz by Buoy users who experienced spontaneous bone pain. This list does not constitute medical advice and may not accurately represent what you have.

Skeletal tuberculosis

Skeletal tuberculosis is an infectious (bacterial) disease caused most often by a the human tubercular baccilus known as mycobacterium tuberculosis. This type of tuberculosis spreads through the blood, and has the capacity to affect most joints in the body (except perhaps the jaw bone).

Rarity: Ultra rare

Top Symptoms: shoulder pain, back pain, joint pain, hip pain, knee pain

Urgency: Primary care doctor

Paget disease of the bone

Paget disease of bone is also called PDB, osteitis deformans, or osteodystrophica deformans. It is normal for bone cells to renew themselves throughout life, but in PDB the renewal becomes disordered. New bone cells are produced too quickly, causing the bones to become weakened and overgrown.

The cause of PDB is not known. It may be due to an inherited trait combined with certain viral infections.

Symptoms include enlargement, bowing, and abnormal curving of the bones, with pain and tenderness. The skull, pelvis, spine, and upper arms and thighs are most often affected. However, many patients have no symptoms and the condition is discovered while assessing something else.

If not treated, Paget disease of bone can lead to bone deformity; fractures; osteoarthritis; and hearing loss due to changes in the small bones within the ear.

Diagnosis is made through blood tests and an x-ray or CT scan.

There is no cure, but symptoms can be managed with medication, pain relievers, physical therapy, and sometimes surgery.

Rarity: Common

Top Symptoms: new headache, pelvis pain, back pain, spontaneous bone pain, moderate hip pain

Symptoms that always occur with paget disease of the bone: spontaneous bone pain

Urgency: Primary care doctor

Osteogenic sarcoma

Osteogenic sarcoma is a cancer of the bone that usually develops when bones are rapidly growing during adolescence. It is the most common primary tumor of the bone. Although any bone in the body can be affected, the thigh (femur), upper arm (humerus), shin (tibia), and pelvis are mo...

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Lung cancer (non-small cell)

Lung cancer is one of the leading causes of cancer-related deaths in the U.S. and worldwide. In 2012, lung cancer was diagnosed in 1.8 million people and caused approximately 1.6 million deaths. When someone is diagnosed with lung cancer, one of the first steps is to stage the disease in order to determine both treatment and prognosis. Ninety-five percent of all lung cancers can be categorized as “small cell” or “non-small cell.” About 10 to 15 percent of lung cancers are considered small cell lung cancers while 80 to 85 percent are non-small cell lung cancers. Cancer, in general, is a condition characterized by overgrowth of a certain cell type. Our bodies naturally have a variety of cell types to serve different functions. The distinction between small cell and non-small cell lung cancer can be determined by looking at a small sample of the lung tissue where the cancer is growing and determining what cell type is overgrowing. Based on the stage of the lung cancer, surgical resection may offer the best outcomes. There are a number of symptoms associated with lung cancer that will be discussed in this article, the most common of which being cough.

Rarity: Rare

Top Symptoms: cardinal symptoms of lung cancer like chest pain or changes in breathing, fatigue, cough, shortness of breath, chest pain

Urgency: Primary care doctor

Gaucher's disease

Gaucher's disease is the result of a buildup of certain fatty substances in certain organs, particularly the spleen and liver. This causes these organs to become much larger than normal and can affect their function.

Rarity: Rare

Top Symptoms: joint pain, spontaneous bone pain, thigh pain, hip pain that comes and goes, fever

Urgency: Primary care doctor


Rickets causes soft, weak bones in children. It usually occurs when they do not get enough vitamin D, which helps growing bones absorb the minerals calcium and phosphorous.

Rarity: Rare

Top Symptoms: muscle aches, irritability, fatigue, spontaneous bone pain, patchy hair loss

Urgency: Primary care doctor


Hyperparathyroidism is a disorder in which the parathyroid glands in the neck are overactive and produce too much parathyroid hormone (PTH). This hormone causes calcium to be released from bones and into the blood.

Rarity: Rare

Top Symptoms: fatigue, abdominal pain (stomach ache), depressed mood, irritability, nausea or vomiting

Urgency: Primary care doctor

Real-life Stories

Once your story is reviewed and approved by our editors, it will live on Buoy as a helpful resource for anyone who may be dealing with something similar. If you want to learn more, try Buoy Assistant.

Questions Your Doctor May Ask About Spontaneous Bone Pain

To diagnose this condition, your doctor would likely ask the following questions:

  • Have you been feeling more tired than usual, lethargic or fatigued despite sleeping a normal amount?
  • Have you had any changes in your weight?
  • Have you lost your appetite recently?
  • Have you had kidney stones before?

If you've answered yes to one or more of these questions

Spontaneous Bone Pain Symptom Checker

Take a quiz to find out what might be causing your spontaneous bone pain

Spontaneous Bone Pain Symptom Checker Statistics

People who have experienced spontaneous bone pain have also experienced:

  • 6% Fatigue
  • 3% Muscle Aches
  • 3% Joint Pain

People who have experienced spontaneous bone pain were most often matched with:

  • 36% Skeletal Tuberculosis
  • 36% Osteogenic Sarcoma
  • 27% Paget Disease Of The Bone

Source: Aggregated and anonymized results from Buoy Assistant (a.k.a. the quiz).

Spontaneous Bone Pain Symptom Checker

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