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VESIcare

(VEH-sih-care)

For the treatment of overactive bladder

Disclaimer

The content on this page is not medical advice and should be used for informational purposes only. Always consult your health care provider or pharmacist to determine what medication and dosage are right for you.

Last updatedJuly 27, 2021

VESIcare

VESIcare is an antispasmodic drug used to treat overactive bladder, such as incontinence, in adults. In children, it is taken to treat neurogenic detrusor overactivity, a bladder disorder.

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Generic name

Solifenacin succinate
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Rx or OTC

Available by prescription only

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When & How

  • Take 5 mg once a day with water.
  • If you tolerate the drug well, your doctor may increase to a maximum of 10 mg daily if needed.
  • If you have any type of kidney or liver disease, the maximum recommended daily dose is 5 mg.
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Do’s

  • Take the tablet whole (do not crush or chew).
  • Before each dose of the oral suspension formulation (for children), shake the bottle well. Use an oral syringe for the proper measurements.
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Don’ts

  • If you miss a dose, do not take a dose if more than 12 hours have passed since the dosing time. Skip that dose and take your next dose as usual.
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Discuss with your doctor

  • If you experience constipation or any severe abdominal pain for more than 3 days while taking VESIcare
  • If you have blurred vision while taking this drug
  • If  you experience confusion and/or headache while taking VESIcare
  • Any signs of urinary tract infection such as a persistent urge to urinate, burning sensation while urinating, cloudy urine
  • If you have severe narrow-angle glaucoma—you should not take this drug.
  • If you have severe liver or kidney disease. Your doctor should choose a different drug or, depending on the severity, recommend a low dose.
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What is VESIcare?

VESIcare is for overactive bladder, which causes symptoms of urinary incontinence, urgency, or frequency.

It helps reduce contractions or spasms of the muscles in the bladder.

It is also taken for neurogenic detrusor activity in children, a bladder disorder.

It is available by prescription only.

VESIcare dosages
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Tablets & liquid

  • 5 mg tablet
  • 10 mg tablet
  • 5mg/5ml suspension

Similar drugs to VESIcare

  • Darifenacin Extended Release
  • Fesoterodine Extended Release
  • Oxybutynin Immediate Release
  • Oxybutynin Extended Release
  • Oxybutynin Transdermal
  • Tolterodine Extended Release
  • Trospium Extended Release
  • Trospium Immediate Release

Side effects

Disclaimer

Medications may affect individuals differently. Usage of any medication may include side effects and other interactions. Here is a list of known common side effects and interactions. This list is not exhaustive -- there may be other side effects or interactions for this medication that are not listed here. In some cases, the likelihood of side effects or interactions may increase depending on dosage. It’s important to keep in mind that in extreme cases, other serious side effects, even death, may occur. Always consult your health care provider or pharmacist to determine what medication and dosage is right for you.

Dry mouth (taking 10 mg)

28% of people experience dry mouth

Constipation (taking 10 mg)

13% of people experience constipation

Blurred vision (taking 10 mg)

5% of people experience blurred vision

Urinary tract infection (taking 10 mg)

5% of people experience urinary tract infection

Indigestion (taking 10 mg)

4% of people experience indigestion

Nausea (taking 10 mg)

3% of people experience nausea

Dizziness (taking 10 mg)

2% of people experience dizziness

Dry eyes (taking 10 mg)

2% of people experience dry eyes

Fatigue (taking 10 mg)

2% of people experience fatigue

Full list of side effects

  • Dry Mouth
  • Constipation
  • Nausea
  • Indigestion
  • Upper abdominal pain
  • Vomiting
  • Urinary tract infection
  • Influenza
  • Pharyngitis
  • Dizziness
  • Blurred vision
  • Dry eyes
  • Urinary retention
  • Lower limb edema
  • Fatigue
  • Depression
  • Cough
  • High blood pressure

Long-term complications

  • Long-term use may interfere with the treatment of Alzheimer's disease who are on medications to promote cholinergic activity.

Safety notes

  • When beginning treatment, may cause central nervous system side effects such as headache, confusion, or hallucinations. If this occurs, call your doctor and stop taking VESIcare. Your doctor may reduce the dose.
  • May impair vision. Do not drive or operate heavy machinery until you know how VESIcare affects you.
  • May cause drowsiness. Do not drive or operate heavy machinery until you know how VESIcare affects you.
  • There is a risk of overheating in hot weather or when exercising.
  • Not recommended when there’s bladder obstruction as this may increase the risk of urinary retention.
  • People with decreased gastrointestinal motility may have severe abdominal pain or constipation. Contact your doctor if you are constipated or have severe pain for more than 3 days.
  • Rare risk of an allergic reaction such as anaphylaxis or angioedema (swelling of face, lips, tongue, throat).
  • There is a risk for QT prolongation (a heart rhythm disorder) based on the dose of VESIcare you are taking.

What else you should know

  • Grapefruit juice seems to increase the level effects of VESIcare, so limit how much you drink.

VESIcare interactions

Disclaimer

Medications may affect individuals differently. Usage of any medication may include side effects and other interactions. Here is a list of known common side effects and interactions. This list is not exhaustive -- there may be other side effects or interactions for this medication that are not listed here. In some cases, the likelihood of side effects or interactions may increase depending on dosage. It’s important to keep in mind that in extreme cases, other serious side effects, even death, may occur. Always consult your health care provider or pharmacist to determine what medication and dosage is right for you.

Tell your doctor if you are taking any of these medications or supplements

  • CYP3A4 inhibitors may increase VESIcare concentrations.
  • CYP3A4 inducers may decrease VESIcare concentrations.

Tell your doctor if you have any of these pre-existing conditions

  • Alzheimer's disease
  • Kidney disease
  • Liver disease
  • History of QT prolongation
  • Narrow-angle glaucoma

VESIcare pricing

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References