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Am I Losing My Mind? Here’s How Anxiety Mimics the Fear of Schizophrenia

anxiety mimics schizophrenia
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Written by Andrew Le, MD.
Medically reviewed by
Last updated July 18, 2025

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Anxiety and schizophrenia may seem like two very different things. One is a common feeling that many people experience from time to time. The other is a serious mental health disorder that affects how someone sees and understands the world. But what if anxiety and schizophrenia are more connected than they appear?

According to studies, intense anxiety is often present at the very beginning of schizophrenia, even before any clear signs of psychosis. This early phase is called the prodromal phase, and it can last for days, months, or even years. During this time, people may feel anxious, confused, or emotionally numb. Some may start noticing that the world around them looks or feels different in strange and unsettling ways.

These changes can be deeply frightening. What’s more, they may not be caused by outside danger, but by how the brain processes what it sees. Some researchers believe that when our ability to find pleasure or make sense of our surroundings breaks down, the world can suddenly feel unsafe or even threatening. This confusion and fear might push the brain to create explanations, sometimes in the form of delusions.

In this article, we’ll explore how anxiety can feel like the beginning of schizophrenia. We’ll look at the science behind this link and what it means for people who live with deep anxiety or fear that they may be losing touch with reality.

Anxiety in the Early Phase of Schizophrenia

Before schizophrenia shows its full symptoms, many people go through a confusing early stage called the prodromal phase. This phase often includes strong anxiety and strange changes in how the world looks or feels. Researchers believe these early signs may help us understand how anxiety connects to schizophrenia.

Here are the key findings from different studies:

  • Experts found that patients described objects and spaces as suddenly looking unfamiliar, even though they had seen them many times before.
  • People in the prodromal phase often experience disturbing changes in how they see the world, leading to deep anxiety.
  • Studies observed that early visual changes, like shifts in color or contrast, can seem harmless at first but later cause overwhelming anxiety as perception breaks down.
  • Anxiety often shows up before other symptoms of schizophrenia, especially in people with a high genetic risk for the condition.
  • Anxiety has also been linked to the risk of psychotic relapse, meaning it may not only appear at the start but also signal a possible return of symptoms later on.

These studies suggest that anxiety is more than just a feeling—it may be one of the brain’s first warning signs that something is going wrong with how it sees and understands the world.

The Role of Anhedonia

Anhedonia is the loss of the ability to feel pleasure. It’s more than just feeling bored—it’s when things that once felt rewarding, exciting, or comforting no longer bring any joy. This may seem unrelated to how we see the world, but researchers believe that anhedonia plays a powerful role in how the brain processes what it sees and understands.

According to studies, pleasure helps the brain organize and rebuild the visual world. Every moment, our brains piece together changing sights—like shadows, angles, and movement—to help us recognize shapes and spaces. When we feel pleasure, our brain works harder to make sense of what it sees.

But when anhedonia takes over:

  • The brain loses interest in solving visual puzzles, like understanding foreshortened shapes or hidden parts of objects.
  • Recognition of familiar patterns becomes weaker or slower.
  • The motivation to connect pieces of information fades, making the world feel less predictable.
  • Small distortions in the environment may go unnoticed until they suddenly feel overwhelming or threatening.

Anhedonia is common in both schizophrenia and anxiety. Berridge and Robinson explain that dopamine, a chemical tied to reward and motivation, plays a major role. When dopamine drops—often due to stress—the ability to enjoy things fades. This lack of pleasure may cause the brain to stop trying to understand its surroundings, making reality seem unstable.

This could help explain why people with deep anxiety sometimes describe feeling like something is wrong with the world, even if they can't say what. Their brains may no longer be fully engaged in interpreting what they see, and this breakdown may quietly build fear.

Stress, Dynorphin, Anhedonia, and Anxiety

Stress doesn’t just make you feel overwhelmed—it also changes how your brain works. When stress is intense or long-lasting, it sets off a chain reaction inside your body. Chemicals like adrenaline, cortisol, and a lesser-known hormone called dynorphin get released. These chemicals are meant to protect you, but sometimes they cause more harm than help.

According to experts, dynorphin plays a major role in this process. It lowers dopamine levels in the brain’s reward system, especially in an area called the nucleus accumbens. Dopamine is what helps you feel motivated and enjoy things. So when dynorphin reduces dopamine, it causes anhedonia—the loss of pleasure.

But that’s not all dynorphin does:

  • It activates certain receptors in the brain that trigger anxiety.
  • It may make people feel on edge even when nothing dangerous is happening.
  • It can leave someone stuck in a state of fear, tension, or emotional shutdown.

Researchers like Chavkin have found that blocking dynorphin in animal studies leads to fewer signs of anxiety. This shows that dynorphin may directly cause fear, not just by removing pleasure, but also by affecting the brain’s anxiety centers, like the amygdala.

What does this mean for you? If you’ve ever felt deeply anxious without knowing why, stress and dynorphin could be playing a role. When your brain can’t feel pleasure and keeps signaling danger, everyday life can feel like something is wrong—even if you can’t explain it.

Delusions as the Brain’s Way of Making Sense of Fear

When fear becomes too intense and the world no longer makes sense, the brain may try to protect itself. One way it does this is by creating delusions—firm beliefs that are not based in reality. These are not random or meaningless. Delusions may be the brain’s attempt to bring order to a confusing and frightening world.

Imagine feeling like something terrible is about to happen, but you don’t know what or why. That feeling can be overwhelming. Some people in the early stages of schizophrenia describe a sudden moment of “clarity,” when all the fear seems to finally make sense. This moment, called an “aha” experience, brings relief because the brain has created a new explanation, often in the form of a delusional belief.

Here’s how delusions may develop:

  • The brain feels flooded with fear, it can’t explain
  • It searches for a reason behind the confusion and fear.
  • A false—but-meaningful—belief forms to explain the strange experience.
  • This belief, though incorrect, helps calm the anxiety by giving it a purpose.

According to studies, these delusions can help organize a person’s thoughts and give structure to a world that feels broken. For example, someone might believe they’re being tested or controlled because it explains why everything feels so wrong. Even if the belief is not true, it offers a story that helps reduce fear.

Interestingly, researchers have noticed that anxiety sometimes fades once delusions appear. This supports the idea that delusions are a coping tool—a mental strategy the brain uses to survive emotional chaos. It may not be accurate, but it can bring temporary peace when fear becomes too much to bear.

When Anxiety Looks Like the Start of Schizophrenia

Not all anxiety is part of a mental illness. But in some cases, it can look and feel like something more serious is happening. For people at risk of schizophrenia, anxiety may not just be a stress reaction—it may be an early sign that the brain is struggling with deeper changes.

According to studies, anxiety is often seen during the prodromal phase of schizophrenia and even right before a psychotic relapse. This shows that anxiety might be part of the illness itself, not just something that happens alongside it. Jones and colleagues found that people with a higher genetic risk for schizophrenia often show high levels of anxiety long before any clear signs of psychosis appear.

Here’s how anxiety can resemble the beginning of schizophrenia:

  • It may appear suddenly and feel out of proportion to what’s happening.
  • It may come with feelings of dread or fear that can’t be explained.
  • It may involve intense sensitivity to surroundings, sounds, or people.
  • It may include thoughts that feel strange, disconnected, or hard to control.

What makes this more confusing is that anxiety and schizophrenia often share symptoms. Both may include paranoia, emotional numbness, and anhedonia (the loss of pleasure). But the difference lies in the cause. In anxiety, paranoia comes from fear of real-life problems. In schizophrenia, paranoia often comes from delusional beliefs, where the brain invents explanations that aren’t based in reality.

This overlap can make it hard to know where one condition ends and the other begins. For some people, anxiety may be a warning. For others, it may be part of the illness itself. Recognizing this early connection could help doctors treat anxiety before it turns into something more serious.

Bottom Line

Anxiety and schizophrenia may seem very different, but science shows they can be closely connected. For some people, deep anxiety comes before the more serious signs of schizophrenia. This fear may start when the brain struggles to process what it sees or loses the ability to feel pleasure. When the world begins to look or feel “off,” fear can grow quickly. If this sounds familiar, it might be a sign to get help. Understanding this link gives us a better chance to catch problems early and stop them from getting worse.

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The stories shared below are not written by Buoy employees. Buoy does not endorse any of the information in these stories. Whenever you have questions or concerns about a medical condition, you should always contact your doctor or a healthcare provider.
Jeff brings to Buoy over 20 years of clinical experience as a physician assistant in urgent care and internal medicine. He also has extensive experience in healthcare administration, most recently as developer and director of an urgent care center. While completing his doctorate in Health Sciences at A.T. Still University, Jeff studied population health, healthcare systems, and evidence-based medi...
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