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Minoxidil vs Finasteride: A Comparison of Staple Hair Loss Treatments

Minoxidil vs Finasteride
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Written by Andrew Le, MD.
Medically reviewed by
Last updated May 10, 2024

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Hair loss used to be a life sentence. But hair loss treatments have come a long way in the last several years. Minoxidil and finasteride are the powerhouses at the forefront of hair regrowth, but which one is best for you?

Minoxidil and finasteride are very different treatments, but there are tradeoffs. This article will explore the pros and cons of each medication, review potential side effects, and give you the information you need to determine the best treatment for you.

Key Takeaways

  • Minoxidil and finasteride are popular treatments for male pattern hair loss, and each is effective in different ways.
  • Minoxidil is a topical solution that stimulates hair follicle growth and is most effective for early-stage hair loss or thinning.
  • Finasteride is an oral medication that inhibits the hormonal cause of hair thinning. It stops follicles from shrinking, preventing and potentially reversing balding.
  • Both minoxidil and finasteride require consistent use to be effective.
  • If you stop taking either medication, your hair loss will return.
  • Minoxidil’s side effects include potential scalp irritation or unexpected hair growth in areas other than the scalp.
  • Finasteride’s potential side effects may lead to decreased libido and erectile dysfunction.

Understanding Minoxidil

Minoxidil is a popular topical medication that’s used on the scalp to treat male pattern hair loss, also known as androgenic alopecia. It’s marketed under several brands and is most commonly known as Rogaine.

Minoxidil is most effective during the early stages of hair loss or if you have gradual thinning. It works by dilating your scalp’s blood vessels to allow more oxygen, blood, and other nutrients to your hair follicles, making them stronger, encouraging hair regrowth, and stabilizing hair growth over time. You may experience more hair loss before you see hair growth, but that’s simply the process of pushing out old, thin hairs to make room for new hair growth. With consistent treatments, you can expect to see an increase in your hair's thickness and coverage after a few months.

Minoxidil is available in both a 2% and 5% topical solution. The higher solution is more effective, although it can have more irritating side effects, which may be a concern if your skin (or scalp) is sensitive.

Pros and Cons of Minoxidil

One key advantage of minoxidil, especially the more potent 5% solution, is how well it helps hair grow. There will typically be a noticeable increase in hair density.

Side effects of minoxidil include scalp irritation and initial hair loss. And while it can be distressing to lose hair you’re trying to regrow, the effect is usually temporary. More serious side effects are rare and include facial or body hair, dizziness, a fast or irregular heartbeat, fainting, chest pain, swelling of hands or feet, weight gain, and tiredness.

Minoxidil does require you to apply the greasy solution twice a day with your hands, and you may have to figure out a new hair regime.

Understanding Finasteride

Finasteride is an oral medication that targets the hormonal cause of male pattern baldness by inhibiting testosterone's conversion to DHT, the hormone that is mainly responsible for hereditary hair loss. Finasteride not only stops the progression of baldness, it also encourages regrowth.

Pros and Cons of Finasteride

Finasteride is convenient as it only requires you to take a small tablet once a day—no cream to spread on your scalp.

Like minoxidil, finasteride is not a cure but a treatment that you’ll need to take for the rest of your life. If you stop taking the medication, you may lose the hair you’ve gained, and your thinning may continue.

Effectiveness and Results

Finasteride has been shown in numerous studies to slow down hair loss significantly and even promote regrowth. However, how effective it is can vary depending on how severe your hair loss is when you begin treatment. And while some people notice an improvement within several months, many don’t see visible results for a year.

Potential Side Effects

As with any medication, finasteride comes with potential side effects. The most common ones involve sexual health. Some men might experience decreased libido or erectile dysfunction during their treatment. You should discuss these potential side effects with a healthcare professional before using this medication.

Another point to consider is that discontinuing use may lead to the recurrence of hair loss. Considering long-term usage and personal commitment to the treatment is paramount.

Making the Decision: Minoxidil vs Finasteride

If you’re considering taking either minoxidil or finasteride, thoroughly understanding how they stack up against one another will help you choose the treatment that suits you best. The best choice will ultimately depend on your individual preferences and should involve a consultation with your healthcare provider.

The Mechanism of Minoxidil and Finasteride

Minoxidil is a topical solution that primarily focuses on stimulating hair follicle growth. The exact mechanism is not fully understood, yet it's believed to extend the growth phase of the hair follicle. The results are potentially thicker hair and slower thinning.

Finasteride is an oral medication that tackles the issue at the hormonal level by inhibiting the conversion of testosterone to DHT, an androgen responsible for hair thinning. Finasteride not only stops the progression of baldness but also encourages regrowth.

Evaluating Efficacy and Side Effects

Results for both minoxidil and finasteride can vary greatly. It might take a few months to notice a difference for minoxidil, but it may take up to a year before you see significant changes with finasteride. Side effects of finasteride, while generally rare, can result in decreased libido and erectile dysfunction. Scalp irritation and excess hair growth in areas other than the scalp are minoxidil’s most common side effects.

Conclusion

Neither minoxidil nor finasteride is a one-size-fits-all solution. Both have their merits for treating male pattern hair loss. Minoxidil can kickstart hair growth sooner, but finasteride offers the potential for more robust regrowth. Weigh the side effects carefully due to the potential implications of finasteride's side effects on your sexual health. Consult with a trusted healthcare professional who knows your medical history, and don’t forget that stopping treatment can reverse your hard-won hair regrowth, so it's not a decision to make lightly.

Frequently Asked Questions

What is the main difference between minoxidil and finasteride?

Minoxidil is a topical solution that stimulates hair follicle growth, and finasteride is an oral medication that prevents hair thinning and promotes regrowth by inhibiting the conversion of testosterone to DHT.

When can results be seen from minoxidil and finasteride?

Results from minoxidil can usually be seen within months, while it can take up to a year to see the effects of finasteride.

Are there side effects of minoxidil and finasteride?

Yes, the side effects differ between the two treatments. Finasteride could potentially affect your libido and cause erectile dysfunction. Minoxidil’s side effects are likely to cause scalp irritation.

Should I consult with a healthcare professional before using minoxidil or finasteride?

Consulting with a healthcare professional is always advised when considering new treatment decisions.

What happens if I stop using minoxidil or finasteride?

Stopping or changing treatments can reverse the progress of hair regrowth so that you’ll likely return to the same level of hair loss you had before you began treatment.

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Jeff brings to Buoy over 20 years of clinical experience as a physician assistant in urgent care and internal medicine. He also has extensive experience in healthcare administration, most recently as developer and director of an urgent care center. While completing his doctorate in Health Sciences at A.T. Still University, Jeff studied population health, healthcare systems, and evidence-based medi...
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