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If you’re in pain, blame your nerves, which send pain signals to your brain. But your nerves also deserve thanks for keeping you safe. They alert you to dangers like extreme heat—or even a bug crawling on your skin.

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A pinched nerve means that something is putting pressure on a nerve, causing pain, numbness, or loss of function. Pinched nerves can occur anywhere in your body from your back to your legs to your wrists.
ALS is a condition that affects nerve cells, leading to eventual loss of control over muscle function. Symptoms include muscle twitches, cramps or weakness.
Sciatica describes any shooting pain that begins at the spine and travels down the leg. The most common cause is a herniated or "slipped" disc in the lower spine.
Guillain-Barre syndrome is a condition in which the body's immune system damages parts of neurons. Symptoms include progressive weakness, numbness or tingling, decreased reflexes, body aches, double vision, loss of balance, and other serious symptoms.
Diabetic neuropathy is nerve damage caused by longstanding or poorly controlled diabetes and other conditions. Symptoms include a loss of sensation, weakness, pain, nausea, and more. Learn which symptoms can be treated.
Mitochondrial myopathies are a group of neuromuscular diseases caused by damage to the mitochondria. Symptoms include exercise intolerance and muscle weakness.