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Unlocking the Secret to Longevity: The Role of Physical Performance in Octogenarians

The Role of Physical Performance in Octogenarians
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Written by Andrew Le, MD.
Medically reviewed by
Last updated May 30, 2024

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A recent study, published in the Journal of the American Geriatrics Society, has unveiled a significant connection between physical performance and the longevity of adults aged 80 years and older. This groundbreaking research comes from the "Aging and Longevity in the Sirente geographic area" (ilSIRENTE) study, which offers fascinating insights into the factors contributing to reaching the age of 95 and beyond.

Originating from the collaborative efforts of experts at the Università Cattolica del Sacro Cuore and the Fondazione Policlinico Universitario “Agostino Gemelli” IRCCS in Rome, Italy, the ilSIRENTE study assessed 195 community-dwelling octogenarians. On average, participants joined the study at 82.3 years old, with women making up approximately two-thirds of the study group.

Researchers utilized comprehensive tools such as the Minimum Data Set for Home Care and the Short Physical Performance Battery (SPPB) to measure participants' physical abilities. The SPPB test, which includes balance, gait speed, and chair-stand tests, helped categorize individuals' functional impairment levels ranging from severe to absent.

Surprisingly, traditional predictors like the number of diseases an individual had did not significantly forecast their chances of becoming a nonagenarian. Instead, the study revealed that those who lived to 95 or older generally exhibited superior physical performance, maintained a higher body mass index, and showed lower levels of disability. Additionally, these long-term survivors consumed fewer medications and exhibited lower levels of the inflammatory marker interleukin 6 (IL6).

A noteworthy finding is that none of the participants who lived beyond 95 suffered from heart failure, highlighting the potential implications of specific health conditions on mortality. Moreover, survival rates were closely linked to physical performance, with Cox regression analyses underscoring the predictive quality of higher SPPB scores and faster gait speed for decreased mortality risks.

The implications of this research are far-reaching, reinforcing the concept that maintaining physical capability well into old age may be more critical for longevity than the mere management of chronic diseases. Consequently, this may shift the focus of healthcare providers towards promoting physical fitness as a priority in geriatric care.

The ilSIRENTE study's discovery, supported by the Italian Ministry of Health—Ricerca Corrente 2023 and the European Commission's Next Generation EU initiative, marks a significant step forward in our understanding of aging and longevity.

For a more detailed look into this illuminating study, the full article can be accessed through the Wiley Online Library or by visiting https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/jgs.18941.

These findings serve as a beacon of knowledge, guiding us to invest in physical health as a pathway to a longer and healthier life. It is through studies like this that we can extend our vision of a vibrant old age for future generations.

This news article was crafted with the assistance of Buoy Health.


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Jeff brings to Buoy over 20 years of clinical experience as a physician assistant in urgent care and internal medicine. He also has extensive experience in healthcare administration, most recently as developer and director of an urgent care center. While completing his doctorate in Health Sciences at A.T. Still University, Jeff studied population health, healthcare systems, and evidence-based medi...
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References

Cacciatore, S., Calvani, R., Marzetti, E., Picca, A., Russo, A., Tosato, M., & Landi, F. (2024). Physical performance is associated with long-term survival in adults 80 years and older: Results from the ilSIRENTE study. Journal of the American Geriatrics Society, 1-5. https://doi.org/10.1111/jgs.18941