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Vigorous Exercise: A Double-Edged Sword for Weight Management

Vigorous Exercise for Weight Management
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Written by Andrew Le, MD.
Medically reviewed by
Last updated June 18, 2024

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Exercise is universally acknowledged as beneficial for physical and mental health. It's an essential component in the fight against obesity, a giant looming over global health. The generally accepted notion was simple: exercise leads to weight loss. However, new research led by Daisuke Funabashi and colleagues at the University of Tsukuba, Japan, which has been accepted for publication in "Medicine & Science in Sports & Exercise®," presents an intriguing twist to this belief. It appears that intense exercise might paradoxically contribute to weight gain, rather than weight loss.

This study, funded primarily by the Japan Society for the Promotion of Science and the Japan Science and Technology Agency, delved into the effects of acute vigorous exercise on non-exercise physical activity (NEPA), body temperature, and ultimately, body weight. Researchers implanted mice with activity monitors to track their NEPA and body temperature for two days before and three days after a 30-minute treadmill session designed to simulate moderate and vigorous exercise.

The findings, available in full glory at http://journals.lww.com/acsm-msse, were startling. Only the mice subjected to vigorous exercise exhibited a decline in both NEPA and body temperature, which led to weight gain the following day. Surprisingly, this occurred without any apparent changes in their food intake.

The study reveals that vigorous exercise might throw off the body's carefully tuned balance, disturbing the NEPA and body temperature remarkably — a dynamic duo that usually works in tandem. A prime suspect behind the scenes is corticosterone, a hormone that shows a circadian rhythm similar to physical activity. Researchers noticed a strong correlation between corticosterone levels post-exercise and changes in NEPA across all exercise groups, sparking a hypothesis that disturbances in corticosterone's rhythm could be a key player.

This research stands as a pioneer in redefining the role of exercise intensity in health benefits beyond simply burning calories. It opens doors to a slew of new questions. Do the outcomes translate to long-term effects on weight for those who regularly engage in vigorous exercise? Could light-intensity exercise be the unsung hero that promotes both NEPA and brain health? As the researchers propose, future studies need to tackle these queries head-on to sculpt an optimal exercise strategy for a physically active lifestyle and effective weight management.

For those intrigued by the full spectrum of data and discussions behind these conclusions, additional information can be sought from Dr. Takashi Matsui at the University of Tsukuba.

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Jeff brings to Buoy over 20 years of clinical experience as a physician assistant in urgent care and internal medicine. He also has extensive experience in healthcare administration, most recently as developer and director of an urgent care center. While completing his doctorate in Health Sciences at A.T. Still University, Jeff studied population health, healthcare systems, and evidence-based medi...
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References

Funabashi, D., Dobashi, S., Sameshima, K., Sagayama, H., Nishijima, T., & Matsui, T. (2024). Acute Vigorous Exercise Decreases Subsequent Non-Exercise Physical Activity and Body Temperature Linked to Weight Gain. Medicine & Science in Sports & Exercise. Advance online publication. http://doi.org/10.1249/MSS.0000000000003487