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How do you know when it’s time to replace your albuterol inhaler?

when to replace albuterol inhaler
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Written by Andrew Le, MD.
Medically reviewed by
Last updated November 26, 2025

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Have you ever pressed your inhaler, felt a weak spray, and wondered if it was still working? Many people overlook the signs that their albuterol inhaler needs replacement until it fails at the worst moment, right in the middle of an asthma attack.

Knowing when your inhaler is running low, clogged, or expired is not just good practice. It’s important for your safety. If the dose counter is wrong, if the spray feels weak, or if the medicine inside loses its strength, your body might not get what it needs to breathe freely.

Why does the dose indicator matter so much?

Most modern albuterol inhalers come with a dose counter or dose indicator that tracks how many puffs you’ve taken. Each spray releases a set amount of medicine, typically 120 mcg from the valve and 108 mcg from the mouthpiece, which equals 90 mcg of albuterol base.

Each canister usually contains 200 inhalations, and the counter moves after every 10 sprays. Watching this number closely helps you know when your medication supply is getting low.

Ignoring the counter might make you think your inhaler still works, even when it’s empty. That can be dangerous, especially if an asthma attack hits unexpectedly.

What does it mean when the indicator turns red?

Source: Lupin

When the background of your dose counter changes to red, your inhaler is nearly empty. That is a warning.

The red signal means you need to refill your prescription soon. Don’t wait until it stops working altogether. A nearly empty inhaler might not release a full dose, leaving you under-treated when you need relief most.

Once you notice the red indicator, contact your pharmacy or doctor immediately. Having a backup inhaler ensures you’re never left unprotected.

What if the counter reads “20” or “0”?

When the number hits 20, it means you only have a few doses left, you’re at the tail end of the canister’s life. Plan your refill now before it runs out.

But when the indicator reaches 0, the inhaler is completely empty. It may still spray air, but it will not deliver medicine. Continuing to use it at this stage is risky.

For example, with Ventolin HFA, the manufacturer advises replacing the inhaler once the counter shows 020, since that’s the final warning before you run out. When it reaches 000, stop using it immediately. Even a small delay could mean facing an asthma attack without proper medication.

Why does my inhaler spray weakly or not at all?

Have you ever pressed down and noticed a weak spray or none at all?

That’s often a sign of medicine build-up inside the actuator, the plastic part that releases the mist.

When residue collects, it can block the nozzle. The counter may still move, making it seem like medicine is coming out, but the spray might contain little or no medication.

If that happens, stop and clean the inhaler before using it again. A weak spray means the medicine isn’t reaching your lungs properly, which can make your symptoms worse.

What should you do if the counter moves but no medicine comes out?

Sometimes the counter moves even though you don’t see any mist. That means the inhaler recognized a press, but the nozzle was clogged. You technically used a dose, but none entered your lungs.

This can trick you into thinking you’re protected when you’re not. The solution is simple:

  1. Clean your inhaler immediately
  2. Remove the canister
  3. Rinse the actuator under warm water
  4. Let it air dry completely
  5. Only then should you reassemble it

If the spray still feels weak after cleaning, your inhaler might be too blocked or worn out. At that point, replacement is the safest option.

Can you still use an expired inhaler?

You might see the expiration date and think, “It still sprays, so it must work, right?” Unfortunately, that’s not always true.

Every inhaler has a printed expiration date that marks when its active ingredients start to degrade. Even if the device still sprays, the medication may lose potency. This means your body won’t get the full benefit during an asthma episode.

A study using high-performance liquid chromatography (HPLC) found that many expired albuterol and montelukast inhalers still contained more than 90% of the active ingredient. Still, that doesn’t guarantee full strength. Even a small loss of potency can mean slower relief, especially during a severe attack.

Manufacturers like Ventolin HFA warn against using expired devices because the medicine may not deliver correctly. Once your inhaler reaches its expiration date, replace it immediately; there are no exceptions.

What happens if you use an expired or weak inhaler?

If you rely on an expired inhaler, you may not notice problems right away. But during an asthma flare-up, the difference becomes clear. The spray might feel lighter, and the medicine may not work fast enough.

This can lead to poor symptom control, increased shortness of breath, or even emergency situations. The safest practice is to always have a fresh, unexpired inhaler on hand and discard the old one as soon as it expires.

How can you keep your inhaler clean and working properly?

Proper cleaning is essential. A dirty inhaler won’t deliver medicine evenly, even if it’s full.

Here’s how to keep it clear and reliable:

  1. Remove the canister from the plastic actuator. Never let the metal canister get wet.
  2. Take off the mouthpiece cap and rinse the plastic part under warm running water for about 30 seconds.
  3. Clean the actuator by running water through it for another 30 seconds, then flip it and rinse again.
  4. Shake off excess water and inspect the mouthpiece. If residue remains, repeat the rinse.
  5. Let it air dry overnight before reassembling. Never use heat to dry it.

If you clean your inhaler regularly but still notice poor spray performance, it may be worn out. A healthy inhaler should release a full, clear mist with each press.

How many puffs does an albuterol inhaler contain?

Most albuterol inhalers deliver 200 puffs, but counting them accurately matters. Some inhalers come with built-in dose counters, but not all.

If yours doesn’t, you can manually track your doses:

  • Keep a small notebook or use your phone to record each use.
  • Replace your inhaler once you reach 200 puffs, even if it still sprays air.

Why is this important?

Because the pressure inside the canister can make it look full even after the medicine is gone. Continuing to use it means you’re inhaling mostly propellant, not the actual medication.

A study found that integrated dose counters were highly accurate, with an error rate of just 0.76%, and 92% of patients said these counters helped them avoid running out. So, if possible, choose an inhaler with a built-in tracker.

So, when should you get a new inhaler?

  • Replace your inhaler when the dose counter turns red or reaches zero.
  • Do not rely on sprays after “0” — the medicine is gone.
  • If the spray weakens or stops, clean the actuator and test again.
  • Never use expired inhalers, even if they still spray.
  • Track every puff and replace after 200 uses to stay accurate.

Clean weekly to prevent blockages and ensure full delivery.

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Jeff brings to Buoy over 20 years of clinical experience as a physician assistant in urgent care and internal medicine. He also has extensive experience in healthcare administration, most recently as developer and director of an urgent care center. While completing his doctorate in Health Sciences at A.T. Still University, Jeff studied population health, healthcare systems, and evidence-based medi...
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