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Learn about your severe fatigue, including causes and common questions. Or get a personalized analysis of your severe fatigue from our A.I. health assistant. At Buoy, we build tools that help you know what’s wrong right now and how to get the right care.

Severe Fatigue Checker

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Your Severe Fatigue May Also be Known as:
Extreme fatigue
Extreme lethargy
Extremely tired
Horrible fatigue
Severe lethargy
Severely tired

Top 9 Severe Fatigue Causes

  1. 1.Mononucleosis Infection

    EBV Mononucleosis is a clinical syndrome characterized by fever, sore throat, and swollen lymph nodes.

    You should visit your primary care physician within the next 24 hours. Diagnosis is confirmed by looking for antibodies against EBV. Treatment involves supportive care (hydration, antipyretics, and analgesics, such as acetaminophen and ibuprofen). Aspirin should not be given to children because of the possibility of Reye syndrome. It is also recommended that you do not do any strenuous physical activity and contact sports in the initial 3 to 4 weeks of illness due to the potential for splenic rupture.

    Rarity:
    Common
    Top Symptoms:
    fatigue, headache, loss of appetite, abdominal pain (stomach ache), cough
    Symptoms that never occur with mononucleosis infection:
    rectal bleeding
    Urgency:
    Primary care doctor
  2. 2.Influenza

    Influenza, or Flu, is an infection of the airway caused by the flu virus, which passes through the air and enters the body through the nose or mouth. The symptoms are similar to those of a cold, but the flu is usually more serious.

    If your flu-like symptoms are existing for less than 48 hours, it might be helpful to seek care by telephone or in a walk-in-clinic to get a course of oseltamivir (Tamiflu). Most people will get better on their own by drinking lots of fluids and taking an over-the-counter medication such as acetominophen (Tylenol) to help with aches or fever.

    Rarity:
    Common
    Top Symptoms:
    fatigue, headache, loss of appetite, cough, muscle aches
    Symptoms that never occur with influenza:
    headache resulting from a head injury
    Urgency:
    Phone call or in-person visit
  3. 3.Heart Attack in a Woman

    Most heart attacks happen when a clot in the coronary artery blocks the supply of blood and oxygen to the heart. Often this leads to an irregular heartbeat - called an arrhythmia - that causes a severe decrease in the pumping function of the heart.

    You should call 911.

    Rarity:
    Uncommon
    Top Symptoms:
    nausea, abdominal pain (stomach ache), pain in one arm, being severely ill, shortness of breath
    Urgency:
    Emergency medical service
  4. 4.Chronic Fatigue Syndrome

    Chronic fatigue syndrome is a disease that causes unexplained fatigue that does not improve with rest.

    While there is no cure, symptoms can be managed with medication & lifestyle changes.

    Rarity:
    Rare
    Top Symptoms:
    fatigue, severe fatigue, trouble sleeping, muscle aches, impaired social or occupational functioning
    Symptoms that always occur with chronic fatigue syndrome:
    fatigue, impaired social or occupational functioning
    Symptoms that never occur with chronic fatigue syndrome:
    mild fatigue, fever
    Urgency:
    Primary care doctor

    Severe Fatigue Checker

    Take a quiz to find out why you’re having severe fatigue.

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  5. 5.Hyperglycemic Hyperosmolar Syndrome (Hhs)

    Hyperosmolar hyperglycemic state is a very serious sudden complication of type 2 diabetes in which blood sugar is dangerously high.

    This is a medical emergency. You will most likely be admitted to the hospital and receive fluids and electrolytes.

    Rarity:
    Rare
    Top Symptoms:
    nausea or vomiting, being severely ill, severe fatigue, fruity odor on breath, frequent urination
    Symptoms that always occur with hyperglycemic hyperosmolar syndrome (hhs):
    being severely ill
    Urgency:
    Emergency medical service
  6. 6.Mononucleosis Infection

    EBV Mononucleosis is a clinical syndrome characterized by fever, sore throat, and swollen lymph nodes.

    You should visit your primary care physician within the next 24 hours. Diagnosis is confirmed by looking for antibodies against EBV. Treatment involves supportive care (hydration, antipyretics, and analgesics, such as acetaminophen and ibuprofen). Aspirin should not be given to children because of the possibility of Reye syndrome. It is also recommended that you do not do any strenuous physical activity and contact sports in the initial 3 to 4 weeks of illness due to the potential for splenic rupture.

    Rarity:
    Rare
    Top Symptoms:
    fatigue, headache, loss of appetite, abdominal pain (stomach ache), cough
    Symptoms that never occur with mononucleosis infection:
    rectal bleeding
    Urgency:
    Primary care doctor
  7. 7.Adrenal Insufficiency

    The adrenal gland's outer layer produces hormones such as cortisol and aldosterone, which control many important functions of the body such as blood sugar and blood pressure regulation, and urine production. In adrenal insufficiency, not enough of these hormones are produced, leading to symptoms such as fatigue and weakness, appetite and weight loss, nausea, and vomiting.

    You should visit your primary care physician who will coordinate your care with a specialist. Adrenal insufficiency is a complex condition that is treated with hormone replacement therapy.

    Rarity:
    Rare
    Top Symptoms:
    depressed mood, loss of appetite, fatigue, nausea or vomiting, anxiety
    Urgency:
    Primary care doctor
  8. 8.Adrenal Insufficiency

    The adrenal gland's outer layer produces hormones such as cortisol and aldosterone, which control many important functions of the body such as blood sugar and blood pressure regulation, and urine production. In adrenal insufficiency, not enough of these hormones are produced, leading to symptoms such as fatigue and weakness, appetite and weight loss, nausea, and vomiting.

    You should visit your a physician or Emergency Room as soon as possible today where blood test will probably be take to look at the 'salts' (elektrolytes) in your blood. Adrenal insufficiency is a complex condition that is treated with hormone replacement therapy.

    Rarity:
    Rare
    Top Symptoms:
    abdominal pain (stomach ache), nausea or vomiting, loss of appetite, being severely ill, vomiting
    Symptoms that always occur with adrenal insufficiency:
    being severely ill
    Urgency:
    Hospital emergency room
  9. 9.Aplastic Anemia

    Aplastic anemia occurs when the body stops creating enough blood cells

    You should seek immediate medical care at your primary care physician or an urgent care, where diagnostic tests (blood tests) can be done and if needed a referral to a hospital can be made.

    Rarity:
    Rare
    Top Symptoms:
    being severely ill, fever, new headache, racing heart beat, severe fatigue
    Symptoms that always occur with aplastic anemia:
    being severely ill
    Urgency:
    In-person visit

Questions Your Doctor May Ask About Severe Fatigue

  • Q.Is your fatigue getting any better or worse?
  • Q.Is your fatigue constant or come-and-go?
  • Q.How long has your fatigue been going on?
  • Q.Any fever today or during the last week?

If you've answered yes to one or more of these questions, check our severe fatigue symptom checker.

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Severe Fatigue Symptom Checker Statistics

  • People who have experienced severe fatigue have also experienced:

    • 5% Nausea
    • 4% Headache
    • 3% Fatigue
  • People who have experienced severe fatigue had symptoms persist for:

    • 34% Over a Month
    • 24% Less Than a Week
    • 19% Less Than a Day
  • People who have experienced severe fatigue were most often matched with:

    • 11% Influenza
    • 4% Mononucleosis Infection

People Who Have Experienced Severe Fatigue Also Read

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    Severe Fatigue Checker

    Take a quiz to find out why you’re having severe fatigue.

    Take a quiz