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Myofascial Pain Syndrome

What is causing your muscles aches and how to treat it.
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Written by Petros Efthimiou, MD, FACR.
New York Rheumatology Care, PC
Medically reviewed by
Last updated April 17, 2024

Myofascial pain syndrome quiz

Take a quiz to find out if you have myofascial pain syndrome.

Care Plan


First steps to consider

  • If you have symptoms of myofascial pain syndrome, like deep, constant muscle pain and knots that cause pain to radiate, you should see a healthcare provider to get a treatment plan.
  • Treatment typically includes a combination of medications, trigger point injections, exercise, massage, and physical therapy.
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Symptom relief

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  • OTC anti-inflammatory medications like ibuprofen (Advil, Motrin) can help relieve muscle tightness.
  • Stretching and massage of the tense area can also help relieve muscle tension.
  • Placing a heating pad on sore muscles can be soothing and help relax the muscle.
See home treatments

What is myofascial pain syndrome?

Myofascial pain syndrome (MPS) is a chronic pain disorder that usually affects a specific group of muscles in your body. It’s caused by tight, contracted bands of fibers in your muscles called “myofascial trigger points.”

The pain feels like a deep constant ache. When trigger points are pressed, the pain can radiate to surrounding areas. You may also feel a burning or stinging sensation.

MPS is often confused with fibromyalgia, which causes pain throughout the body, not just in a specific area, and does not usually have trigger points.

Most common symptoms

You may feel a pain in one muscle group or part of your body, like the lower back, neck, or jaw.

Main symptoms

  • Pain
  • Muscle stiffness
  • Trigger points (they may feel like muscle knots or tenderness to pushing down on a particular spot)

Pro Tip

Myofascial pain syndrome is often confused with fibromyalgia, a more generalized condition. They share many common characteristics, such as the type of pain and the presence of tender points. However, MFS usually affects specific muscle groups/areas of the body. —Dr. Petros Efthimiou

What causes myofascial pain syndrome?

MPS seems to be set off by some type of event, such as a muscle spasm, a muscle injury, or continual muscle stress (overuse). These may lead to the development of contracted muscle fibers, which become trigger points. The prolonged contraction creates inflammation, which may lead to a painful knot. This is why poor posture is often cited as a cause of myofascial pain syndrome. The posture leads to a prolonged contraction, leading to the knot and corresponding discomfort. As we will discuss later, therapies are aimed at relieving inflammation and improving the function of the muscle and fascia in the area.

Pro Tip

Ask your doctor: Is there a particular posture, exercise, repetitive movement that causes pain and muscle spasm in the area of my body affected by MFS? Can non-pharmacologic approaches (change of posture, avoidance of a particular exercise/movement) help resolve it? —Dr. Efthimiou

What makes you more likely to have MPS?

Factors that may contribute to the development of MPS:

  • Poor posture
  • Sitting for a long time in awkward positions
  • Nutritional deficiencies (e.g. vitamin deficiencies, electrolyte abnormalities)
  • Any injury to the musculoskeletal system (muscles, bones, tendons) or disks in the spine
  • Fatigue and lack of sleep
  • Hormonal changes (menopause)
  • Intense cooling of muscles (such as when sleeping in front of an air conditioner)
  • Stress and mental health issues (depression, anxiety)
  • Underlying inflammatory diseases
  • Obesity

What is the best treatment for myofascial pain?

Treatment for MPS typically includes a combination of drugs, trigger point injections, exercise, massage of pressure and trigger points, and physical therapy.

  • Stretching. A physical therapist may lead you through gentle stretching exercises through a tolerable range of motion to help the management of muscle pain. If you have trigger point pain when stretching, the physical therapist may spray a numbing solution on your skin.
  • Massage. Massaging the tight muscles manually or by acupressure or the use of a massage percussion device (massage gun) applied directly on trigger points may offer instant pain relief and release muscle tension. This is likely due to the improving movement of fascia.
  • Heat. Apply heat using a heat pack or warm towel to the painful area to help relieve muscle tension and reduce pain.
  • Therapeutic ultrasound. Use of sound waves may increase blood circulation and warm the area, which can bring relief and promote healing in muscles.
  • Dry/wet needling. Inserting a needle (dry needling) into the trigger point may break up the tension. Sometimes a numbing agent or steroid is used (wet needling).
  • Acupuncture. Speaking of needles, acupuncture is the practice of inserting thin, solid, metallic needles through the skin combined with gentle movements by the practitioner's hands.


  • Muscle relaxants
  • Nonsteroidal anti-inflammatory drugs (NSAIDs)
  • Trigger point injections
  • Analgesics (lidocaine patches) applied on affected muscle groups
  • Anticonvulsants (lidocaine, pregabalin)
  • Antidepressants (duloxetine)
  • Botox injections to affected areas

Here are some over-the-counter (OTC) treatments to help manage this pain from the comfort of your home.

  • Anti-Inflammatory Medications: Products like ibuprofen can reduce inflammation and relieve muscle tightness. They're easily accessible and can make a significant difference in your comfort levels.
  • Heat Therapy: A simple heating pad can work wonders by soothing your sore muscles and helping them relax. This is an easy way to get some relief, especially during flare-ups.
  • Topical Pain Relievers: Gels or creams containing lidocaine can numb the pain locally, providing temporary but effective relief. These are great for targeting specific areas that hurt the most.

Ready to treat your myofascial pain syndrome?

We show you only the best treatments for your condition and symptoms—all vetted by our medical team. And when you’re not sure what’s wrong, Buoy can guide you in the right direction.See all treatment options
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Dr. Rx

In milder cases, topical injections of the trigger points with local anesthetics (e.g. lidocaine) can release the muscle spasm and relieve the pain, without the need for oral medicines. —Dr. Efthimiou


  • Improving your posture can help treat, but also prevent myofascial pain, particularly in your neck (e.g., “tech neck”). You can improve posture by stretching and avoiding being in the same position for a long period of time.
  • Doing exercises that strengthen the muscles surrounding your trigger point will help avoid muscle overuse.
  • Try to reduce your stress and practice relaxation techniques.
  • Try to keep a regular sleep schedule to improve your sleep.
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The stories shared below are not written by Buoy employees. Buoy does not endorse any of the information in these stories. Whenever you have questions or concerns about a medical condition, you should always contact your doctor or a healthcare provider.
Dr. Le obtained his MD from Harvard Medical School and his BA from Harvard College. Before Buoy, his research focused on glioblastoma, a deadly form of brain cancer. Outside of work, Dr. Le enjoys cooking and struggling to run up-and-down the floor in an adult basketball league.

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