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Top 10 Treatments for IBS

Treatments for IBS
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Written by Andrew Le, MD.
Last updated April 20, 2024

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Irritable bowel syndrome (IBS) is a complex, functional gastrointestinal disorder characterized by various symptoms that can significantly affect individuals' daily lives. These symptoms include abdominal pain, cramping or bloating related to bowel movements, changes in the appearance and frequency of bowel movements, sensation of incomplete evacuation, and increased gas or mucus in the stool.

While the causes are not fully understood, finding an effective treatment can provide much-needed relief and improve the quality of life for sufferers.

This article analyzes the top 10 IBS treatments available on the market today. From dietary supplements to probiotics and specialized formulations, it evaluates products based on ingredients quality, efficacy, pricing, and unique benefits.

Types of IBS

IBS is categorized into different types based on the predominant bowel habit, which is crucial for tailoring treatment:

  1. IBS with Constipation (IBS-C): This type is marked by chronic constipation, where individuals experience infrequent, hard, or lumpy stools, often accompanied by abdominal pain and bloating, which typically lessen following a bowel movement.
  2. IBS with Diarrhea (IBS-D): IBS-D is characterized by frequent, loose, or watery stools, with individuals often feeling an urgent need to have a bowel movement. They may experience pain and discomfort in the abdomen, which can improve after defecation.
  3. Mixed IBS (IBS-M): Individuals with IBS-M experience both constipation and diarrhea, making symptom management particularly challenging due to the unpredictability of their bowel habits.

Causes and Triggers

The exact cause of IBS isn't fully understood. Still, several factors are thought to play a role, including muscle contractions in the intestine, issues with the nervous system, severe infections, early life stress, and changes in gut microbes.

IBS symptoms can be triggered by certain foods, stress, menstrual periods, and other factors such as food intolerance and severe digestive tract infections. People who have experienced physical, sexual, or emotional abuse are also more likely to develop IBS​.

IBS is more common in people under age 50, with a higher prevalence in females. A family history of IBS, along with anxiety, depression, or other mental health issues, can increase the risk of developing this condition​.

Top Treatments for IBS

When selecting treatments for IBS, you must weigh factors such as effectiveness, ingredient quality, and cost to ensure you choose a product that suits your needs. Our detailed analysis of the top treatments for IBS facilitates your decision-making process.

These treatments offer solutions for digestive discomfort, including relief from bloating, constipation, diarrhea, and other IBS symptoms. They utilize a variety of approaches, from dietary supplements to probiotics, targeting different aspects of digestive health. Each product's unique benefits, such as natural ingredient composition, specific formulations for gut lining repair, and the inclusion of clinically tested probiotics, are emphasized, helping you make an informed choice for managing IBS.

IBS Clear™

IBS Clear™ is a breakthrough dietary supplement designed to provide natural relief for Irritable Bowel Syndrome (IBS). This product combines powerful ingredients such as Vitamin D, Psyllium Husk, and Fennel in 60 vegan-friendly capsules per bottle. With a focus on digestive health support, IBS Clear™ aims to alleviate IBS symptoms effectively. The price for a 60-count bottle starts at $44.95, offering an all-in-one solution for those seeking relief from digestive discomfort.


  • Contains natural enzymes to aid in food digestion effectively.
  • Psyllium Husk, a soluble fiber, helps bulk up stool, making it easier to pass through the digestive system.
  • Perilla Leaf and Peppermint Leaf provide additional digestive support, particularly in reducing bloating.
  • Includes Bioperine for enhanced bioavailability, ensuring quicker and easier absorption into the body.
  • Formulated with 100% pure ingredients, free from additives, fillers, colors, or preservatives.
  • Suitable for vegans and made in the USA, ensuring quality and ethical standards.


  • Some users may find the product relatively expensive compared to other IBS supplements on the market.
  • While generally well-tolerated, there may be rare instances of adverse reactions, as with any dietary supplement.
Intestinal Fortitude GLR-6

Intestinal Fortitude GLR-6 is a gut lining repair supplement designed to support gut health and address issues like leaky gut, IBS, IBD, and GERD. The product incorporates a blend of six natural ingredients including L-Glutamine, Slippery Elm, DGL Licorice Root, Marshmallow Root, and Fenugreek, aiming to soothe the irritation and ulceration of the gastrointestinal tract while providing the necessary nutrients for its repair. GLR-6 is available in a bottle containing 120 capsules, with recommended servings of 30, making it suitable for a month's supply.

This supplement is processed in a GMP-compliant facility in the USA and is free from gluten, dairy, GMO, wheat, tree nuts, peanuts, eggs, fish, colorings, or preservatives.


  • GLR-6 is made from natural ingredients known for their gut health benefits.
  • Users report significant improvements in symptoms related to digestive health issues.
  • Contains 2-6 times more of the active ingredients compared to competitors, making it a highly potent option.
  • Specifically formulated to support the repair of the gut's mucosal lining.
  • It is processed in a facility that ensures it's free from common allergens and harmful additives.


  • Some individuals may experience adverse reactions due to the potent nature of the ingredients.
  • At $39.99, it may be considered expensive for some, especially considering it is a monthly supply.
  • The requirement to potentially take multiple capsules daily may be inconvenient for some users.

IBSolution is an all-natural gut health supplement designed to provide relief for irritable bowel syndrome (IBS) symptoms. It helps promote digestive health, relieve constipation, diarrhea, gas, bloating, and stomach pain.

Each bottle contains 60 capsules, which is a 30-day supply when taken as directed. The price for a one-time purchase is $27.95, with the option to save 10-15% through Subscribe & Save.


  • All-natural ingredients sourced from Mother Nature, including walnut hulls, acai, slippery elm, papaya, aloe, inulin, ginger, psyllium, chlorella, lycopene, and hyssop leaf.
  • Formulated with digestive aids and naturally occurring superfoods.
  • Helps regulate bowel movements and promote regularity.
  • Made in the USA and certified by the Natural Products Association.
  • Non-GMO, gluten-free, and vegan.
  • Affordable option compared to expensive prescriptions and medical treatments.


  • Some users may find the price relatively high compared to other over-the-counter supplements.
  • Results may vary from person to person, and not everyone may experience the same level of relief.
  • Non-returnable due to food safety reasons, so there is limited recourse if the product does not meet expectations.
Digestive Advantage IBS Probiotics

Digestive Advantage IBS Probiotics is a supplement designed for both men and women to support digestive health and provide intensive bowel support. It includes a unique blend of probiotics and three types of digestive enzymes (protease, amylase, lipase) aimed at reducing minor abdominal discomfort, occasional bloating, and supporting overall digestive balance.

This product, available in a pack of 96 unflavored capsules, leverages the clinically tested probiotic strain BC30, which is notably resilient against stomach acid, ensuring more probiotics reach the gut to exert their beneficial effects.


  • BC30 is designed to survive stomach acid better than many other probiotics, ensuring it reaches the gut.
  • Aimed at reducing symptoms like minor abdominal discomfort and occasional bloating.
  • Includes both probiotics and digestive enzymes for a broad approach to digestive health.
  • Suitable for vegetarians and those avoiding genetically modified organisms.
  • With continued use, it supports long-term digestive health.


  • Some users might experience constipation as a side effect.
  • Symptoms may return if usage is discontinued; it manages rather than cures digestive issues.
  • Contains wheat and soy, which could be problematic for individuals with allergies or sensitivities to these ingredients.

IBgard is a gut health supplement that comes in the form of peppermint oil capsules. It is designed to provide relief from various digestive symptoms, including cramping, bowel urgency, diarrhea, constipation, bloating, and gas.

The product is clinically shown to offer abdominal comfort and is recommended by gastroenterologists for promoting digestive health. IBgard comes in a pack of 48 capsules and is priced at $26.95 for a single pack.


  • Clinically proven to manage a combination of digestive symptoms.
  • Recommended by gastroenterologists for abdominal comfort.
  • Contains ultrapure peppermint oil, which supports healthy digestion.
  • Utilizes Patented Site-Specific Targeting (SST) technology for effective delivery.
  • Starts providing relief in as little as 24 hours.
  • Safe for daily use and suitable for adults.


  • Some users find the product expensive for the quantity provided.
  • May cause heartburn and reflux in certain individuals.
  • Effectiveness varies among users, with some experiencing limited relief.
  • Capsules may be large and difficult for some individuals to swallow.
  • Not suitable for individuals with peppermint allergies.
  • Requires consistent daily use for optimal results.
SIBO IBS Relief by Flight Armour

The SIBO IBS Relief by Flight Armour is a clinical-grade treatment designed to alleviate symptoms associated with IBS and Small Intestine Bacterial Overgrowth (SIBO). This supplement is formulated to improve abdominal pain, reduce bloating, and stimulate gut recovery. It contains clinically studied ingredients that are safe for individuals with SIBO and IBS.

The product is gluten-free, vegan, non-GMO, and manufactured in the USA. Its patented DR Caps capsule technology ensures maximum potency by delivering the ingredients intact.


  • Customers report significant relief from symptoms such as bloating, gas, and abdominal discomfort.
  • Formulated with ingredients that have been clinically studied for their efficacy in managing SIBO and IBS.
  • Compatible with low FODMAP and elemental diets, as well as antimicrobials and other products like berberine and Quebracho.
  • Suitable for individuals with dietary restrictions and preferences.
  • Patented capsule technology ensures the delivery of ingredients intact for maximum effectiveness.


  • While many customers praise its effectiveness, some express concerns about the value proposition, suggesting that it may be relatively expensive compared to other options.
Innovative Bowel Support for Women

The Innovative Bowel Support for Women is a specialized product designed to alleviate symptoms associated with Irritable Bowel Syndrome (IBS). This product offers relief from common gastrointestinal discomforts such as bloating, gas, constipation, diarrhea, and abdominal pain. Formulated with natural ingredients and manufactured in the USA, it targets a woman's unique digestive needs with its proprietary blend.


  • Tailored specifically for women, this product addresses hormonal imbalances and supports healthy digestion.
  • Formulated with natural ingredients like Ginger, Fennel Seed, and Peppermint, it offers relief without harsh chemicals.
  • The innovative delivery system ensures that active ingredients are released at the right time and location for maximum effectiveness.
  • Beyond alleviating immediate symptoms, it promotes overall digestive health, mood enhancement, and stress relief.
  • Made in the USA, Non-GMO, gluten-free, soy-free, and dairy-free, this product undergoes third-party testing to ensure quality and safety.


  • While many users experience significant relief, individual results may vary, and some users may not find the product as effective for their specific symptoms.
Banatrol Natural Anti-Diarrheal with Prebiotics

Banatrol® Natural Anti-Diarrheal with Prebiotics offers relief from chronic diarrhea, IBS, recurring diarrhea, and other related conditions. This clinically supported medical food is trusted by healthcare professionals worldwide. It effectively stops diarrhea and loose stools without causing constipation, allowing individuals to resume their daily activities without the worry of frequent restroom visits. The product contains clinically proven prebiotics that promote gut health in as few as 7 days.

Recommended for adults and children aged 4 years and older, Banatrol® Plus is a safe and reliable solution for managing diarrhea associated with various conditions, including IBS, food poisoning, stomach bugs, traveler’s diarrhea, flu, C. Diff, and antibiotic use. The product typically comes in a package with 28 servings, priced at approximately $38.99.


  • Stops diarrhea and loose stools fast without causing constipation.
  • Clinically proven medical food recommended by healthcare professionals worldwide.
  • Contains prebiotics that effectively increase gut health in as few as 7 days.
  • Safe for both adults and children aged 4 years and older.
  • Recommended for managing diarrhea associated with various conditions, including IBS, food poisoning, stomach bugs, and more.


  • Some users may find the taste unpleasant, although it is not overly flavored.
  • Mixing the product with water may result in a thick and pasty consistency, which can be unappealing for some individuals.
  • Relatively expensive compared to similar products on the market.
Banatrol Natural Anti-Diarrheal

Medtrition Banatrol Natural Anti-Diarrheal with Prebiotics offers relief for individuals experiencing IBS and recurring diarrhea. This clinically supported food product comes in a pineapple flavor and is available in a 10.5-ounce jar.

This product provides a natural solution to stop diarrhea and loose stools quickly without causing constipation, allowing users to resume their daily activities without worry.


  • Banatrol Plus stops diarrhea rapidly, providing relief without the concern of constipation.
  • Recommended by medical professionals worldwide for over 15 years, it effectively manages diarrhea associated with various conditions, including IBS, food poisoning, stomach bugs, traveler’s diarrhea, flu, C. Diff, and antibiotic use.
  • Contains clinically proven prebiotics that enhance gut health in as little as 7 days.
  • Suitable for both adults and children aged 4 years and older.
  • Apart from general use, it's also recommended for managing diarrhea caused by the side effects of oncology treatments.


  • Some users may find the taste unpleasant, which could affect compliance with the regimen.
  • While many users report positive results, some have experienced adverse effects such as diarrhea and vomiting.
  • Few users have reported discrepancies in the number of servings received compared to what was advertised, which could lead to dissatisfaction.
  • While it works well for many, some users may not experience significant improvement in their condition even after using it for a considerable period.
Hyperbiotics PRO IBS Probiotic Support

Hyperbiotics PRO IBS Probiotic Support is a targeted supplement designed to alleviate symptoms of irritable bowel syndrome (IBS) and promote digestive health. This product offers a convenient solution for those experiencing bloating, gas, and irregularity associated with IBS. Each capsule contains 30 billion CFUs of Lactiplantibacillus plantarum 299v, a clinically effective strain, along with Boswellia serrata extract to support gastrointestinal health.


  • Formulated specifically for individuals with IBS, this supplement provides accelerated and prolonged relief from symptoms such as bloating, gas, and irregularity.
  • The inclusion of L. plantarum 299v, a highly stable and patented probiotic strain, ensures that beneficial bacteria survive the harsh conditions of the gastrointestinal tract to support a healthy intestinal barrier.
  • Backed by over 65 clinical studies, the efficacy of L. plantarum 299v and Boswellia serrata extract has been demonstrated in addressing gut discomfort and dysfunction.
  • Each capsule combines a blend of probiotic strain and bioavailable Boswellia serrata extract, delivering essential nutritional support for gastrointestinal health.
  • This vegan, non-GMO formula is free of dairy, gluten, soy, nuts, and active yeast, making it suitable for individuals with dietary restrictions. It undergoes rigorous testing to ensure safety and potency.


  • As with any supplement, the effectiveness of Hyperbiotics PRO IBS Probiotic Support may vary among individuals, and some users may not experience significant relief from their symptoms.

Final Thoughts

The Intestinal Fortitude GLR-6 supplement is the best overall choice for treating IBS symptoms. This potent, all-natural formula contains high concentrations of gut-healing ingredients like L-glutamine and slippery elm designed to soothe the intestinal lining.

Many users report significant relief from issues like bloating, diarrhea, and abdominal pain after taking GLR-6. While slightly more expensive, its targeted and high-quality formula justifies the cost for those seeking an effective IBS solution. GLR-6's comprehensive approach to gut repair makes it stand out as the top recommended product in this analysis.

Frequently Asked Questions

What kinds of medications are commonly prescribed for IBS?

Medications for IBS vary based on symptoms. For diarrhea, options include loperamide, rifaximin, and eluxadoline. For constipation, fiber supplements, laxatives, and specific drugs like lubiprostone may be recommended. Antispasmodics and antidepressants can help manage abdominal pain​.

Can probiotics help with IBS?

Probiotics, which are live microorganisms, are being studied for their potential to treat IBS. It’s essential to consult with a healthcare provider before starting probiotics to ensure they’re appropriate for your situation.

What are mental health therapies for IBS?

Cognitive behavioral therapy, gut-directed hypnotherapy, and relaxation training are mental health therapies that can help improve IBS symptoms by addressing the psychological aspects contributing to the condition.

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The stories shared below are not written by Buoy employees. Buoy does not endorse any of the information in these stories. Whenever you have questions or concerns about a medical condition, you should always contact your doctor or a healthcare provider.
Dr. Le obtained his MD from Harvard Medical School and his BA from Harvard College. Before Buoy, his research focused on glioblastoma, a deadly form of brain cancer. Outside of work, Dr. Le enjoys cooking and struggling to run up-and-down the floor in an adult basketball league.

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