Read below about unilateral upper leg swelling, including causes and common questions. Or get a personalized analysis of your unilateral upper leg swelling from our A.I. health assistant. At Buoy, we build tools that help you know what’s wrong right now and how to get the right care.

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A.I. Health Assistant Causes for Unilateral Upper Leg Swelling

The list below shows results from the use of our A.I. Health Assistant by Buoy users who experienced unilateral upper leg swelling. This list does not constitute medical advice.

  1. 1.Deep Vein Thrombosis

    Deep vein thrombosis (DVT) is a blood clot that forms in a vein deep in the body. Most deep vein clots occur in the lower leg or thigh.

    Curable with medication or surgery but may recur.

    Rarity:
    Uncommon
    Top Symptoms:
    fever, thigh pain, upper leg swelling, calf pain, butt pain
    Urgency:
    Hospital emergency room
  2. 2.Compartment Syndrome

    Compartment syndrome is a serious condition that involves increased pressure in a muscle compartment. It can lead to muscle and nerve damage and problems with blood flow.

    Prognosis is highly variable after surgery and depends on how rapidly you are treated.

    Rarity:
    Rare
    Top Symptoms:
    arm numbness, hand numbness, foot numbness, pain in one leg, thigh numbness
    Urgency:
    Hospital emergency room

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  3. 3.Cushing Syndrome

    Cushing Syndrome is a hormonal disorder. The cause is long-term exposure to too much cortisol, a hormone that the adrenal gland makes. Sometimes, taking synthetic hormone medicine like corticosteroids to treat an inflammatory disease leads to Cushing's syndrome.

    Recovery depends on treatment method

    Rarity:
    Rare
    Top Symptoms:
    fatigue, headache, depressed mood, weight gain, back pain
    Urgency:
    Primary care doctor
  4. 4.Osteogenic Sarcoma

    Osteogenic sarcoma (osteosarcoma) is a cancer that starts in the bone, and usually affects the ends of the bone where new tissue forms at a growth plate. It is the most common cancerous bone tumor in young people, with the average age at diagnosis being 15 years. Pain in the bone is the most commonly reported symptom.

    Although surgery will treat the cancer, a limb prosthesis will likely need to be used for life.

    Rarity:
    Ultra rare
    Top Symptoms:
    spontaneous bone pain, lower leg bump, upper leg bump, swollen thigh, swollen shin
    Symptoms that always occur with osteogenic sarcoma:
    spontaneous bone pain
    Urgency:
    Primary care doctor

Questions Your Doctor May Ask About Unilateral Upper Leg Swelling

  • Q.Where on your upper leg is this swelling?
  • Q.Have you ever been diagnosed with diabetes?
  • Q.Any fever today or during the last week?
  • Q.Do you have a rash?

If you've answered yes to one or more of these questions, try our unilateral upper leg swelling symptom checker to find out more.

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Unilateral Upper Leg Swelling Symptom Checker Statistics

  • People who have experienced unilateral upper leg swelling have also experienced:

    • 9% Upper Leg Pain
    • 3% Severe Upper Leg Pain
    • 2% Tingling Upper Leg
  • People who have experienced unilateral upper leg swelling had symptoms persist for:

    • 30% Less Than a Week
    • 28% Over a Month
    • 22% Less Than a Day
  • People who have experienced unilateral upper leg swelling were most often matched with:

    • 40% Deep Vein Thrombosis
    • 40% Compartment Syndrome
    • 20% Cushing Syndrome
  • Source: Aggregated and anonymized results from visits to the Buoy AI health assistant (check it out by clicking on “Take Quiz”).

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