Skip to main content

Dyspepsia Treatment Overview

Find the right care and learn about different treatments.
Reviewed by Buoy's medical team
Learn how we choose treatments

Care Plan


First steps to consider

  • Mild, occasional dyspepsia (indigestion) can usually be treated at home.
  • Try OTC medications like antacids and anti-bloating and anti-gas medications.
  • Quit smoking and avoid coffee, carbonated beverages, and alcohol.
See home treatments

When you may need a provider

  • Moderate to severe indigestion
  • Need to take antacids daily
  • Symptoms occur frequently or are affecting your quality of life.
See care providers

Emergency Care

Arrow Icon.

Go to the ER or call 911 if you have any of the following symptoms:

  • Severe nausea and vomiting
  • Bloody or black stools
  • Constant upper abdominal pain

See your doctor right away if you’re over 55 and

  • Have a family history of cancer
  • Stomach pain comes on suddenly and abruptly
  • Can’t swallow or it’s painful to swallow
  • Vomiting frequently
  • Have unexplained weight loss

The suppliers listed follow Buoy’s clinical guidelines, but listing the suppliers does not constitute a referral or recommendation by Buoy. When you click on the link and/or engage with these services Buoy will be compensated.

Stethoscope Inside Circle.


All treatments for dyspepsia
Info Icon.
Read more about dyspepsia care options

When to see a healthcare provider

While mild, occasional episodes of dyspepsia can often be treated at home, you should see a doctor if your symptoms occur frequently, you take antacids most days to treat your symptoms, or the symptoms are interfering with your everyday life.

Your doctor may prescribe medications to control the production of stomach acid. In some cases, cognitive behavior therapy is recommended.

Getting diagnosed

Dyspepsia is diagnosed based on your medical history and a physical exam. If you have severe symptoms, your doctor may recommend having an upper gastrointestinal (GI) endoscopy.

An upper GI endoscopy can help your doctor identify conditions that may be causing your dyspepsia, such as gastritis and peptic ulcer disease. During this test, a small tube called an endoscope is inserted through your mouth. Tiny tools go through the endoscope to take tissue samples of the stomach and the first part of the small intestine.

Other tests your doctor may order include imaging tests (X-rays, ultrasound), blood and stool tests, and a urea breath test.

What to expect from your visit

If OTC medications haven’t helped, your doctor may recommend prescription medications for indigestion.

  • Some prescription medications are stronger versions of the OTC medications that treat mild dyspepsia, such as H2 blockers and proton pump inhibitors (PPIs). Both work by decreasing the amount of acid your stomach produces. PPIs are most effective for people who have dyspepsia and heartburn.
  • Prokinetics may be prescribed to help your stomach empty faster.
  • If tests show that you have a type of bacterial infection (H. pylori) that causes peptic ulcers, your doctor may put you on a course of antibiotics to treat it.
  • Behavior therapy may also be recommended to help you learn to relax and reduce stress, which helps prevent dyspepsia. Types of therapy include cognitive-behavioral therapy, biofeedback, and hypnotherapy.

Prescription dyspepsia medications

  • H2 blockers: famotidine (Pepcid/Zantac), cimetidine (Tagamet)
  • Proton pump inhibitors: pantoprazole (Protonix), rabeprazole (AciPhex), esomeprazole (Nexium), lansoprazole (Prevacid), omeprazole(Prilosec)
  • Antibiotics for H. pylori: amoxicillin (Amoxil), clarithromycin (Biaxin), metronidazole (Flagyl)
  • Prokinetics: bethanechol (Urecholine), metoclopramide (Reglan)

Types of providers

  • A primary care provider can treat mild to moderate symptoms.
  • A gastroenterologist specializes in diagnosing and treating conditions involving the digestive tract.
Showing results for
Meet Buoy's physicians and clinicians
Every treatment shown on this site is evaluated by our medical team and must pass Buoy's clinical review.
Learn how we choose treatments
FAQ Icon.


Frequently asked questions