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Top 8 Best B6 Supplements

UpdatedJuly 23, 2024

Vitamin B6, also known as pyridoxine, is an essential nutrient that plays a crucial role in several bodily functions. It helps maintain healthy brain function, supports the immune system, and aids in the production of red blood cells. While vitamin B6 can be found in certain foods such as poultry, fish, and bananas, many people choose to supplement their intake to ensure they are meeting their daily recommended intake.

When it comes to choosing the best B6 supplement, there are a few critical factors to consider. The first is the form of vitamin B6 used in the supplement. There are three main forms: pyridoxine hydrochloride, pyridoxal-5-phosphate, and pyridoxamine. Pyridoxal-5-phosphate is the most active form and is often preferred by those who have trouble converting pyridoxine hydrochloride to its active form.

Another important factor to consider is the dosage. The recommended daily intake of vitamin B6 for adults is 1.3-1.7 mg, but some supplements contain much higher doses. It's important to choose a supplement with a dosage that aligns with your individual needs and to consult with a healthcare provider before taking high doses of any vitamin.

We spent hours researching and testing various B6 supplements to identify the ones that are the most effective and reliable. In the following sections, we will share our top picks for the best B6 supplements on the market, taking into account factors such as form, dosage, and overall quality.

Top 3 Best B6 Supplements

  1. Pure Encapsulations B6 Complex
  2. NOW Supplements, Vitamin B-6 (Pyridoxine HCl) 100 mg
  3. Solgar Vitamin B6 25 mg, 100 Tablets

We have researched and compiled a list of the best B6 supplements available on Amazon. Vitamin B6, also known as pyridoxine, is an essential nutrient that plays a vital role in maintaining a healthy immune system, brain function, and metabolism. It is commonly found in foods such as fish, poultry, potatoes, and bananas, but sometimes it can be challenging to get enough of this vitamin from diet alone. That's where supplements come in handy. In this article, we will highlight the top B6 supplements that can help you meet your daily recommended intake and improve your overall health and well-being.


Pure Encapsulations B6 Complex

Editor's Choice

Pure Encapsulations B6 Complex

Pure Encapsulations B6 Complex offers premium quality, expert-guided nutrition. It's free from common allergens and supports cognitive function, nerve health, and more. However, large capsules and occasional dizziness may be drawbacks. Yet, if you seek top-notch B6 support, it's worth the investment.

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We highly recommend Pure Encapsulations B6 Complex for anyone looking for a high-quality B6 supplement to support their overall health.

Pros

  • Supports healthy cognitive function and proper functioning of the nervous system.
  • Important in amino acid metabolism, hemoglobin formation, nerve impulse transmissions, and hormone synthesis.
  • Includes ingredients to support healthy methylation and neurological health.

Cons

  • Large capsules may be difficult for some to swallow.
  • May cause dizziness in some individuals.
  • More expensive than other B6 supplements on the market.

We were impressed with the premium quality of Pure Encapsulations B6 Complex. The supplement contains only the highest quality ingredients sourced from trusted suppliers and is guided by nutritional experts. We appreciate that it is free from wheat, eggs, tree nuts & peanuts, gluten, artificial colors, flavors & sweeteners, coatings and shellacs, GMOs, and unnecessary binders, fillers & preservatives.

Pure Encapsulations B6 Complex supports healthy cognitive function and proper functioning of the nervous system. It is also important in amino acid metabolism, hemoglobin formation, nerve impulse transmissions, and hormone synthesis. The supplement includes ingredients to support healthy methylation and neurological health.

One downside is that the capsules are quite large and may be difficult for some individuals to swallow. Additionally, some users have reported feeling dizzy after taking the supplement. Finally, the price point is higher than other B6 supplements on the market.

Overall, we believe that Pure Encapsulations B6 Complex is a great choice for anyone looking for a high-quality B6 supplement to support their overall health.


NOW Supplements, Vitamin B-6 (Pyridoxine HCl) 100 mg, Cardiovascular Health*, 250 Veg Capsules 250 Count (Pack of 1)

NOW Supplements, Vitamin B-6 (Pyridoxine HCl) 100 mg, Cardiovascular Health*, 250 Veg Capsules 250 Count (Pack of 1)

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If you're looking for a reliable Vitamin B6 supplement, NOW Supplements Vitamin B-6 (Pyridoxine HCl) 100 mg is definitely worth considering.

Pros

  • Supports healthy homocysteine metabolism
  • Important for nervous system function
  • Cardiovascular health benefits

Cons

  • May melt or get damaged if exposed to heat or sunlight during delivery
  • Some people may experience side effects like nausea or stomach pain
  • Not suitable for people with certain medical conditions or taking certain medications

We've been using this supplement for a while now and have noticed a significant improvement in our overall health and wellbeing. The supplement is easy to take and doesn't have any unpleasant taste or aftertaste.

One of the biggest advantages of this supplement is that it supports healthy homocysteine metabolism, which is important for maintaining cardiovascular health. It's also essential for normal synthesis of hemoglobin and red blood cells, and for regulating nervous system function.

However, it's important to note that this supplement may melt or get damaged if exposed to heat or sunlight during delivery. Additionally, some people may experience side effects like nausea or stomach pain, especially if they take high doses or have certain medical conditions.

Overall, we would definitely recommend NOW Supplements Vitamin B-6 (Pyridoxine HCl) 100 mg to anyone looking for a high-quality Vitamin B6 supplement that can help support their overall health and wellbeing.


Solgar Vitamin B6 25 mg, 100 Tablets - Supports Energy Metabolism, Heart Health & Healthy Nervous System - B Complex Supplement - Vegan, Gluten Free, Dairy Free, Kosher - 100 Servings (Pack of 2) 100 Count (Pack of 2)

Solgar Vitamin B6 25 mg, 100 Tablets - Supports Energy Metabolism, Heart Health & Healthy Nervous System - B Complex Supplement - Vegan, Gluten Free, Dairy Free, Kosher - 100 Servings (Pack of 2) 100 Count (Pack of 2)

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If you're looking for a B6 supplement that supports energy metabolism, heart health, and a healthy nervous system, then Solgar Vitamin B6 25 mg, 100 Tablets is a great option.

Pros

  • Promotes heart health by supporting healthy levels of homocysteine
  • Plays an integral role in the production of red blood cells
  • Suitable for Vegetarians

Cons

  • Exposure to heat or sunlight may lead to melting/damage of product
  • The below information is per pack only
  • None

I've been using Solgar Vitamin B6 25 mg, 100 Tablets for a few weeks now, and I've noticed an improvement in my energy levels. Along with folic acid and B12, B6 promotes heart health by supporting healthy levels of homocysteine. I appreciate that this supplement is suitable for vegetarians, so it's a great option for those who follow a plant-based diet.

One thing to keep in mind is that exposure to heat or sunlight may lead to melting/damage of the product, so it's important to store it properly. Additionally, the below information is per pack only, so it's important to read the label carefully to ensure that you're getting the right amount of B6.

Overall, I would recommend Solgar Vitamin B6 25 mg, 100 Tablets to anyone looking for a B6 supplement to support energy metabolism, heart health, and a healthy nervous system.


Divine Bounty Super B Complex Vitamins

Divine Bounty Super B Complex Vitamins

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If you're looking for an affordable and high-quality B-complex supplement, Divine Bounty Super B Complex Vitamins are an excellent choice.

Pros

  • Our extra strength formula contains all the essential B Vitamins in just one capsule, making it a more potent source of B-Complex vitamins.
  • With 90 capsules per bottle, Divine Bounty offers one of the best value vitamin B supplements available.
  • Our formula is made up of only pure ingredients with no harmful additives, making it a safe and clean formula.

Cons

  • Some users may experience a change in urine color due to the high levels of B vitamins in the supplement.
  • The capsules may be too large for some users to swallow easily.
  • Some users may not see noticeable results immediately and may need to take the supplement for a few weeks before noticing any difference.

We've been using Divine Bounty Super B Complex Vitamins for a few weeks now and have noticed a significant improvement in our energy levels and overall well-being. The extra strength formula contains all the essential B vitamins, including B12, B1, B2, B3, B5, B6, B7, B9, and folic acid, making it a more potent source of B-complex vitamins.

One of the best things about this supplement is the value for money it offers. With 90 capsules per bottle, it's one of the best value vitamin B supplements available. Additionally, the formula is made up of only pure ingredients with no harmful additives, making it a safe and clean formula.

While some users may experience a change in urine color due to the high levels of B vitamins in the supplement, it's a small price to pay for the benefits it provides. However, some users may find the capsules too large to swallow easily. Additionally, some users may not see noticeable results immediately and may need to take the supplement for a few weeks before noticing any difference.

Overall, we highly recommend Divine Bounty Super B Complex Vitamins as a supplement you can take with confidence. It's proudly made in the USA in an inspected facility, and the company stands behind its product. If it doesn't work for you, let them know. They care about your results.


Nature Made Vitamin B6 100 mg

Nature Made Vitamin B6 100 mg

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If you're looking for a high-quality B6 supplement, Nature Made Vitamin B6 100 mg tablets are worth considering.

Pros

  • Supports energy metabolism
  • Helps with proper red blood cell formation
  • Supports nervous system function

Cons

  • May cause nasal congestion for some
  • May not be suitable for those with certain medical conditions
  • Some people may find the tablets hard to swallow

We've been using Nature Made Vitamin B6 100 mg tablets for a few weeks now, and we've noticed an improvement in our energy levels. The tablets are easy to take, and we appreciate that they're gluten-free, with no artificial colors or flavors.

While we haven't experienced any negative side effects from taking these tablets, we have heard that some people may experience nasal congestion when taking B6 supplements. Additionally, if you have any medical conditions or are taking any medications, it's always a good idea to check with your doctor before starting any new supplements.

Overall, we think that Nature Made Vitamin B6 100 mg tablets are a solid choice for anyone looking to support their energy levels and overall health. With a USP verification and a good reputation among pharmacists, we feel confident in recommending this product.


Nature's Bounty Vitamin B6

Nature's Bounty Vitamin B6

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If you're looking for a B6 supplement to support your energy metabolism and nervous system health, Nature's Bounty Vitamin B6 is a great choice.

Pros

  • Supports healthy amino acid levels
  • Suitable for vegetarians
  • From a trusted wellness brand

Cons

  • May cause stomach upset if taken on an empty stomach
  • Some users have reported a strong odor from the tablets
  • May not be suitable for those with certain medical conditions

We've been using Nature's Bounty Vitamin B6 for a few weeks now and have noticed an increase in our energy levels throughout the day. We appreciate that it's a vegetarian formula and doesn't contain any artificial flavors. Additionally, we trust the Nature's Bounty brand and appreciate their commitment to quality and scientific research.

One thing to keep in mind is that taking B6 supplements on an empty stomach may cause stomach upset, so it's best to take them with food. Additionally, some users have reported a strong odor from the tablets, although we didn't notice this ourselves. As with any supplement, it's important to check with your healthcare provider before taking it, especially if you have any medical conditions or are taking any medications.

Overall, we would recommend Nature's Bounty Vitamin B6 to anyone looking for a high-quality B6 supplement to support their energy levels and overall health.


Life Extension Pyridoxal 5'-Phosphate 100 mg P5P – Essential Vitamin B6 For Heart, Nerve & Eye Health – Glucose & Blood Sugar Supplement - Gluten-Free, Non-GMO - 60 Vegetarian Capsules 60 Count (Pack of 1)

Life Extension Pyridoxal 5'-Phosphate 100 mg P5P – Essential Vitamin B6 For Heart, Nerve & Eye Health – Glucose & Blood Sugar Supplement - Gluten-Free, Non-GMO - 60 Vegetarian Capsules 60 Count (Pack of 1)

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If you are looking for a supplement to support healthy nerve, eye, cardiovascular and kidney function, Life Extension Pyridoxal 5'-Phosphate 100 mg P5P might be the right choice for you.

Pros

  • METABOLICALLY ACTIVE B6 - Vitamin B6 plays an important role in many of your body’s essential processes. Pyridoxal 5’-phosphate is the metabolically active form of vitamin B6.
  • GLYCATION AND AGEs (AND AGING) – “Glycation” is when blood sugar reacts with proteins and lipids in your body to create advanced glycation end products, or AGEs. Your body can’t use AGEs for anything, so they simply accumulate...and contribute to the physiological effects of aging. Vitamin B6 helps inhibit glycation reactions—which helps keep you young on the inside.
  • BRAIN, KIDNEY & EYE HEALTH – Turns out, inhibiting glycation has nearly system-wide benefits. Doing so supports eye, heart and brain health. It also helps encourage healthy kidney function, and can even help your body mount a more effective and healthy immune response.

Cons

  • Might not be suitable for people who are allergic to any of the ingredients.
  • Taking too much vitamin B6 can cause nerve damage and other serious side effects.
  • Some customers reported that the capsules are hard to swallow.

Life Extension Pyridoxal 5'-Phosphate 100 mg P5P is a great supplement to support healthy nerve, eye, cardiovascular and kidney function. The metabolically active form of vitamin B6 in this supplement can help inhibit glycation reactions and keep you young on the inside. Moreover, it has nearly system-wide benefits for brain, kidney, and eye health. However, it might not be suitable for people who are allergic to any of the ingredients, and taking too much vitamin B6 can cause nerve damage and other serious side effects. Some customers also reported that the capsules are hard to swallow.


EZ Melts Dissolvable Vitamin B6 50 mg, Sugar-Free, 1-Month Supply

EZ Melts Dissolvable Vitamin B6 50 mg, Sugar-Free, 1-Month Supply

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We highly recommend the EZ Melts Dissolvable Vitamin B6 50 mg supplement for anyone looking to support their heart and nervous system health, boost metabolic function, and maintain healthy energy levels.

Pros

  • These dissolvable tablets have a refreshing orange flavor and contain zero sugar, making them easy to take.
  • EZ Melts supplements are made with non-GMO, vegan-friendly ingredients, and are formulated without the use of common allergens such as gluten, dairy, lactose, eggs, nuts, fish, shellfish, and soy.
  • The vitamin B6 50mg per serving tablets are made in the USA at Florida facilities using ingredients that are globally sourced by certified US-based suppliers, ensuring high quality.

Cons

  • Some users may find the chalky texture and strong orange flavor hard to stomach.
  • The tablets may not dissolve easily for some people, requiring them to use water to dissolve them before taking.
  • The supplement may not work for everyone, and results may vary depending on individual needs and health conditions.

If you're looking for a convenient and effective way to boost your vitamin B6 intake, the EZ Melts Dissolvable Vitamin B6 50 mg supplement is an excellent choice. These tablets are easy to take, made with high-quality ingredients, and provide a range of health benefits.

In addition to supporting heart and nervous system health, these supplements can help convert food to fuel, support healthy energy levels, and promote mood balance. Whether you're an athlete looking to improve your performance or simply want to maintain optimal health, the EZ Melts Vitamin B6 supplement is a great choice.

Buying Guide

When looking for the best B6 supplement, there are a few things to consider before making a purchase. Here are some key features to look for:

Form

B6 supplements come in various forms, including tablets, capsules, and gummies. Consider which form is most convenient for you and your lifestyle. For example, if you have trouble swallowing pills, gummies may be a better option.

Dosage

The recommended daily intake of B6 varies depending on age and gender. Make sure to choose a supplement that provides the appropriate dosage for your needs. It's also important to not exceed the recommended dosage, as high levels of B6 can be harmful.

Quality

Look for a supplement that is made by a reputable manufacturer and has been third-party tested for quality and purity. This can help ensure that you are getting a safe and effective product.

Additional Ingredients

Some B6 supplements may also contain other vitamins or minerals, such as B12 or magnesium. Consider whether you need these additional ingredients and if they are included in safe and effective amounts.

Price

Price can vary greatly between different B6 supplements. While it's important to find a supplement that fits within your budget, it's also important to prioritize quality and effectiveness over price.

In summary, when choosing a B6 supplement, consider the form, dosage, quality, additional ingredients, and price. By taking these factors into account, you can find a supplement that meets your needs and helps support your overall health.

Frequently Asked Questions

What is the recommended daily dose for a B6 supplement?

The recommended daily dose of Vitamin B6 varies depending on age and gender. For adults, the recommended daily intake is 1.3-1.7 mg/day. Pregnant and breastfeeding women may require higher doses. It is important to consult with a healthcare professional before taking any supplements to determine the appropriate dosage for your individual needs.

What are the best brands of Vitamin B6 supplements?

There are many reputable brands of Vitamin B6 supplements on the market. Some popular options include Nature Made, Solgar, and NOW Foods. It is important to choose a brand that has been third-party tested for purity and potency.

Can taking too much Vitamin B6 be harmful?

Yes, taking too much Vitamin B6 can be harmful. High doses of Vitamin B6 can cause nerve damage, numbness, and tingling in the hands and feet. The upper limit for daily intake of Vitamin B6 is 100 mg/day for adults. It is important to follow the recommended dosage guidelines and consult with a healthcare professional before taking any supplements.

What are the benefits of taking Vitamin B6 supplements?

Vitamin B6 plays an important role in many bodily functions, including metabolism, immune function, and nervous system health. Some studies suggest that Vitamin B6 may also help reduce symptoms of PMS, improve mood, and support cardiovascular health. However, more research is needed to fully understand the potential benefits of Vitamin B6 supplementation.

Is P5P a more effective form of Vitamin B6 compared to other forms?

P5P, or pyridoxal-5-phosphate, is a biologically active form of Vitamin B6 that is more readily absorbed by the body compared to other forms. However, more research is needed to determine whether P5P is more effective than other forms of Vitamin B6 for specific health conditions.

What is the recommended dosage of Vitamin B6 for relieving pregnancy nausea?

The recommended dosage of Vitamin B6 for relieving pregnancy nausea is 10-25 mg, three times per day. It is important to consult with a healthcare professional before taking any supplements during pregnancy.

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