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Top 14 Best Choline Supplements

Written by Andrew Le, MD

UpdatedMay 29, 2024

Choline is an essential nutrient that plays an important role in several bodily functions, including liver function, brain development, and muscle movement. However, many people don't get enough choline from their diets, which is where choline supplements come in. Choline supplements are designed to provide the body with the necessary amount of choline to maintain optimal health.

When it comes to choline supplements, there are several different types to choose from, including choline bitartrate, alpha-GPC, and citicoline. Each type has its unique benefits and drawbacks, so it's essential to choose the right one for your needs.

One critical factor to consider when purchasing a choline supplement is the purity and quality of the product. Some supplements may contain fillers or other additives that can be harmful to your health. It's essential to choose a supplement that is free from harmful additives and has been tested for purity and potency.

Top 3 Best Choline Supplements

  1. Nested Naturals Choline Supplement
  2. NOW Choline & Inositol Capsules
  3. PURE SYNERGY Choline Complex

If you're looking to boost your cognitive function, improve your memory, or enhance your overall brain health, choline supplements might be worth considering. Choline is an essential nutrient that plays a crucial role in brain development, nerve function, and metabolism. While choline can be found in certain foods like eggs, liver, and soybeans, many people find it challenging to get enough choline from their diet alone. That's where choline supplements come in.

We've researched and tested various choline supplements on the market to bring you the best options available. Whether you're a student looking to improve your focus or an older adult hoping to support your brain health, we've got you covered. Check out our top picks for the best choline supplements below.

Nested Naturals Choline Supplement

The Editor's Choice

Discover Nested Naturals Choline Supplement—a vegan, non-GMO gem supporting brain health & nervous system. Ideal for moms-to-be. Yet, watch for a fishy odor reported by users, misleading labeling (split dosage), and large capsules. Despite quirks, it's a solid option, just mind the caveats before diving in.

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If you're looking for a vegan and non-GMO choline supplement, Nested Naturals Choline Supplement might be a good option for you.

Nested Naturals Choline Supplement is a great way to support your nervous system and brain function. It's especially helpful for pregnant and breastfeeding mothers who need extra choline for their baby's health. Additionally, it can help support your liver and metabolism of fatty acids.

However, some users have reported a strong fish odor with the supplement. The product label can also be misleading, as it suggests that you're getting 180 capsules when in fact the 550mg dose is split between two capsules. Finally, the capsules themselves are quite large, which may be difficult for some users to swallow.

Overall, if you're looking for a vegan and non-GMO choline supplement, Nested Naturals Choline Supplement is a good choice. Just be aware of the potential downsides before making your purchase.

Pros

  • Supports brain and nervous system
  • Contains 500mg of choline for pregnant and breastfeeding mothers
  • Helps support the liver and metabolism of fatty acids

Cons

  • Strong fish odor
  • Misleading product label
  • Capsules are large
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If you're looking for a choline supplement that supports healthy nerve transmission and fatty acid metabolism, NOW Choline & Inositol Capsules are a great option.

I've been taking NOW Choline & Inositol Capsules for a few weeks now, and I've noticed a significant improvement in my overall cognitive function. My memory has improved, and I've been able to focus better on tasks at work. I also appreciate that these capsules are Kosher, Non-GMO, and Soy-Free.

One thing to keep in mind is that the capsules are relatively large, so if you have difficulty swallowing pills, you may want to consider a different choline supplement. Additionally, some users may experience digestive discomfort after taking these capsules, so it's important to start with a lower dose and gradually increase as needed.

While NOW Choline & Inositol Capsules may not be as effective as other choline supplements for certain individuals, I think they're a great option for anyone looking to support healthy nerve transmission and fatty acid metabolism. Overall, I would definitely recommend giving these capsules a try if you're in the market for a choline supplement.

Pros

  • Supports healthy nerve transmission
  • Assists in fatty acid metabolism
  • Kosher, Non-GMO, and Soy-Free

Cons

  • Capsules are relatively large
  • Some users may experience digestive discomfort
  • May not be as effective as other choline supplements for certain individuals
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If you are looking for a choline supplement that is made with organic vegetables and sprouts, and fermented so it’s absorbed just like food, then PURE SYNERGY Choline Complex is a great option.

PURE SYNERGY Choline Complex is a great supplement to promote healthy cognitive function and support brain and nervous system health. It is also important for healthy prenatal brain development. Additionally, it supports healthy liver function as well as healthy bile and fat metabolism.

The tablets are made with organic ingredients, non-GMO, gluten-free, vegan, and dairy-free. However, the tablets are sticky and clumped together, making it hard to get one out. The tablets also have a slight smell, like greens, and are a little big, about 3/4 inch.

Overall, if you are looking for a choline supplement that is made with organic ingredients and supports cognitive and liver health, then PURE SYNERGY Choline Complex is a good option to consider.

Pros

  • Made with organic vegetables and sprouts, and fermented so it’s absorbed just like food.
  • Promotes healthy cognitive function & supports brain & nervous system health.
  • Supports healthy liver function as well as healthy bile & fat metabolism.

Cons

  • Tablets are sticky and clumped together, making it hard to get one out.
  • Tablets have a slight smell, like greens.
  • Tablets are a little big, about 3/4 inch.
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If you're looking for a choline supplement that's good for your brain, liver, and energy metabolism, Solgar Choline/Inositol 500 mg/500 mg is a great choice.

I've been using Solgar Choline/Inositol 500 mg/500 mg for a few months now, and I've noticed an improvement in my energy levels and mental clarity. I take one capsule in the morning with breakfast, and another in the afternoon with a snack. The capsules are easy to swallow, but they do have an unpleasant taste if you don't swallow them quickly.

One thing to note is that this product is not eligible for international shipping, so if you're outside of the US, you'll need to find another choline supplement. Also, if you take these capsules on an empty stomach, you may experience stomach upset, so be sure to take them with food.

Overall, I highly recommend Solgar Choline/Inositol 500 mg/500 mg if you're looking for a choline supplement that's good for your brain, liver, and energy metabolism. It's a high-quality product from a reputable brand, and it's helped me feel more alert and focused throughout the day.

Pros

  • Supports brain and nerve function
  • Promotes normal fat metabolism
  • Helps support energy metabolism

Cons

  • Capsules taste unpleasant
  • Not eligible for international shipping
  • May cause stomach upset if taken on an empty stomach
Order Ritual Natal Choline Now!

If you're an expectant mother searching for a prenatal supplement, Ritual Natal Choline stands out as a noteworthy option. Packed with essential nutrients, this supplement aims to support both maternal and fetal health during pregnancy.

Pros

  • Easy-to-swallow capsules with no aftertaste
  • Choline content for optimal brain development in the fetus
  • Gentle on the stomach, suitable for sensitive pregnant individuals

Cons

  • Slightly higher price compared to other prenatal supplements
  • May not contain all the nutrients found in traditional prenatal multivitamins

The easily digestible capsules without an unpleasant aftertaste are a key advantage of Ritual Natal Choline. The inclusion of choline is particularly commendable, as it plays a crucial role in promoting optimal brain development in the growing fetus. Furthermore, its gentle formula is well-tolerated by those with sensitive stomachs, ensuring a comfortable experience for pregnant individuals.

However, it's essential to note that the price point of this supplement may be slightly higher than alternatives on the market. Additionally, while Ritual Natal Choline focuses on key nutrients, it may not provide the comprehensive range of vitamins and minerals found in traditional prenatal multivitamins.

In conclusion, for expectant mothers seeking a prenatal supplement that prioritizes ease of consumption, choline supplementation, and stomach comfort, Ritual Natal Choline deserves consideration.

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This dietary supplement with 250 mg of Citicoline is a great choice for people looking for daily brain health, performance, and memory support.

This supplement is a great choice for people looking for a subtle but clear improvement in mental energy and focus. It is easy to use, and the suggested use is to take one capsule one or two times a day with food or as directed by your qualified healthcare professional.

The Citicoline in this supplement supports brain energy metabolism and attention performance in healthy adults and adolescents. It is also gluten-free and suitable for people with dietary restrictions.

However, some users reported side effects such as irritability and throat mucus, and it may cause headaches if taken every day. Additionally, better alternatives are available for lesser price.

Overall, if you are looking for a reliable and effective choline supplement for daily brain health, performance, and memory support, Jarrow Formulas Citicoline CDP Choline 250 mg Capsules is a great choice.

Pros

  • Provides daily brain health, performance, and memory support
  • Supports brain energy metabolism and attention performance in healthy adults and adolescents
  • Contains one 120 count bottle of Jarrow Formulas Citicoline CDP Choline 250 mg Capsules for a 60- to 120-day supply

Cons

  • May cause headaches if taken every day
  • Some users reported side effects such as irritability and throat mucus
  • Better alternatives are available for lesser price
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If you're looking for a high-quality choline supplement, NusaPure Choline Bitartrate is definitely worth considering.

Overall, I think NusaPure Choline Bitartrate is a great choice if you're looking for a high-quality choline supplement. The 650 mg per serving is a good amount to get the benefits of choline, and the fact that it's suitable for vegan/vegetarian diets, non-GMO, and gluten-free is a nice bonus. Plus, the fact that it's made in the USA in a cGMP registered facility means you can trust the quality.

That said, some users might find the capsules a bit large to swallow, and a few users have reported mild side effects like headaches or stomach upset. Additionally, the product is a bit more expensive than some other choline supplements on the market.

If you're willing to spend a bit more for a high-quality choline supplement, I definitely recommend giving NusaPure Choline Bitartrate a try.

Pros

  • Provides 650 mg per serving, which is a good amount to get the benefits of choline.
  • Suitable for vegan/vegetarian diets, non-GMO, and gluten-free.
  • Made in the USA in a cGMP registered facility, so you can trust the quality.

Cons

  • Some users might find the capsules a bit large to swallow.
  • A few users have reported mild side effects like headaches or stomach upset.
  • The product is a bit more expensive than some other choline supplements on the market.
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If you're looking for a choline supplement that supports healthy brain and cellular function, then Solgar Choline Supplement could be the right choice for you.

Solgar Choline Supplement is a high-quality supplement that supports brain health and metabolism management. The supplement is unflavored and suitable for vegetarians, making it a great choice for anyone looking for a natural and effective way to support their health.

One of the key benefits of Solgar Choline Supplement is that it is involved in the chemistry of the brain, where it is used to synthesize acetylcholine, a critical neurotransmitter required for brain function. This means that taking this supplement may help support healthy brain function and improve cognitive performance.

Another benefit of Solgar Choline Supplement is that it promotes normal fat metabolism and provides liver support. This makes it a great choice for anyone looking to support their overall health and wellbeing.

However, it's important to note that exposure to heat or sunlight may lead to melting/damage of the product. Hence customers are expected to be available during the product delivery. Additionally, some users may not notice any significant changes, and the supplement may not be suitable for people with bladder/kidney stones.

In conclusion, Solgar Choline Supplement is a great choice for anyone looking for a natural and effective way to support their brain health and metabolism management. With its high-quality ingredients and proven benefits, this supplement is definitely worth considering.

Pros

  • Involved in the chemistry of the brain, where it is used to synthesize acetylcholine, a critical neurotransmitter required for brain function
  • Promotes normal fat metabolism and provides liver support
  • Suitable for Vegetarians

Cons

  • Product Note: Exposure to heat or sunlight may lead to melting/damage of product. Hence customers are expected to be available during the product delivery
  • May not be suitable for people with bladder/kidney stones
  • Some users may not notice any significant changes
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If you're looking for a high-quality choline supplement that supports healthy liver and gallbladder function and the nervous system, then Standard Process Choline might be the right choice for you.

Standard Process Choline is a great option for those looking for a natural supplement that supports overall health. Its unique blend of choline bitartrate and honey provides a range of benefits, including support for methylation reactions, healthy liver and gallbladder function, and a healthy nervous system.

One potential downside of this supplement is that it may cause stomach upset in some individuals. Additionally, some users report not noticing any significant difference after taking it. Finally, those with gallbladder issues may want to consult with their doctor before taking this supplement.

Overall, if you're looking for a high-quality choline supplement that provides a range of benefits, Standard Process Choline is definitely worth considering. With its natural ingredients and proven track record, it's a great choice for anyone looking to support their overall health and wellbeing.

Pros

  • Provides support for methylation reactions
  • Supports healthy liver and gallbladder function
  • Supports a healthy nervous system

Cons

  • May cause stomach upset in some individuals
  • Some users report not noticing any significant difference
  • May not be suitable for individuals with gallbladder issues
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If you're looking for a high-quality choline supplement, the Double Wood Supplements CDP Choline Supplement is a great option that may help support memory formation and retention, working memory, focus, and mental energy.

This supplement is manufactured in the USA and provides 300mg of pharmaceutical-grade CDP Choline per capsule. It's gluten-free and suitable for adults looking to manage their energy levels.

If you're looking for a supplement to support your cognitive function, this product may be worth considering. However, it's important to note that some users may experience side effects such as headaches or stomach upset, and it may not be suitable for those with certain medical conditions.

Overall, if you're looking for a high-quality choline supplement that may help support your memory and cognitive function, the Double Wood Supplements CDP Choline Supplement is definitely worth checking out.

Pros

  • Promotes choline levels effectively
  • Supports memory formation and retention
  • Supports cognitive function

Cons

  • May cause headaches or stomach upset in some individuals
  • May not be suitable for those with certain medical conditions
  • Some users may not experience noticeable benefits
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If you want to improve your mental clarity and focus, NATURAL STACKS Acetylcholine Brain Food can help you achieve your goals.

NATURAL STACKS Acetylcholine Brain Food is a potent and powerful nootropic designed to help your body produce more of “the learning molecule”. It contains Alpha-GPC, a super nootropic clinically studied for mental performance, combined with synergistic vitamins B1 and B5 to provide elite clarity, cognition, and focus.

The formula includes exact ratios of each ingredient found in scientific research, ensuring that it works fast and well. It can be taken as an anytime tune-up to keep your brain running at optimum performance, banishing brain fog and allowing you to think clearly and store more memories.

NATURAL STACKS is #1 in brain supplements, and their formulas contain the finest natural ingredients, transparent open-source labeling, and vigorous third-party testing to ensure purity and potency. Your purchase comes with a 100% happiness guarantee, so if anything goes wrong, simply contact them, and they’ll make it right.

If you’re looking for a high-quality choline supplement to help improve your mental clarity and focus, NATURAL STACKS Acetylcholine Brain Food is definitely worth trying.

Pros

  • Helps improve mental clarity and focus
  • Contains high-quality natural ingredients
  • Comes with a 100% happiness guarantee

Cons

  • Expensive compared to other choline supplements
  • May take some time to see noticeable results
  • May not work for everyone
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If you're looking for a high-potency choline supplement, Horbäach Choline Bitartrate is worth considering.

As someone who has used Horbäach Choline Bitartrate, I can attest to its high potency and quality. The capsules are easy to take, although they may be a bit large for some people. I appreciate that this supplement is free of gluten, artificial flavors, and sweeteners, and that it's non-GMO. I also like that Horbäach is committed to ensuring the purity and potency of their products.

That being said, I do think it's important to note that some individuals may not find this supplement to be effective for their needs. Additionally, as with any supplement, it's important to talk to your healthcare provider before taking Horbäach Choline Bitartrate, especially if you have any medical conditions or are taking any medications.

Overall, if you're looking for a high-quality choline supplement, Horbäach Choline Bitartrate is definitely worth considering. Just be sure to talk to your healthcare provider before taking it to ensure it's safe and appropriate for you.

Pros

  • Provides 410 mg of choline per capsule, which is 75% of the daily value
  • Gluten-free, non-GMO, and free of artificial flavors and sweeteners
  • Backed by Horbäach's commitment to purity and potency

Cons

  • Some users may find the capsules difficult to swallow
  • May not be suitable for individuals with certain medical conditions or who are taking certain medications
  • Some users may not notice significant benefits from taking this supplement
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If you're looking for a quality choline supplement, Horbäach Choline Inositol Supplement might be the right choice for you.

This supplement is expertly crafted and scientifically formulated to provide high-quality Choline Inositol in quick-release capsules. The active compounds found in lecithin and members of the B-vitamin family make this supplement an excellent choice for anyone looking to support their brain health and cognitive function.

One of the best things about Horbäach Choline Inositol Supplement is that it is free of gluten, wheat, yeast, lactose, artificial sweetener, preservatives, and non-GMO. This makes it a great choice for anyone with dietary restrictions or who is looking for a clean and pure supplement.

While this supplement may not be suitable for those with soy allergies, most users report experiencing little to no side effects. With consistent use, this supplement can help improve memory, focus, and overall cognitive function.

Overall, Horbäach Choline Inositol Supplement is a high-quality supplement that can help support brain health and cognitive function. If you're looking for a reliable and effective choline supplement, this might be the right choice for you.

Pros

  • Choline Inositol: Active compounds naturally found in lecithin and members of the B-vitamin family
  • Scientific Formula: Features 1000 mg Choline Inositol per serving in quick release capsules
  • Expertly Crafted: Our professional formula is backed by our commitment to purity and potency

Cons

  • May not be suitable for those with allergies to soy
  • Some users may experience mild side effects such as stomach upset or headaches
  • Requires consistent use to see optimal results
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If you're looking for a choline supplement that supports your memory, attention, and focus, then Klaire Labs CDP Choline 250mg is a great option.

Klaire Labs CDP Choline 250mg is a hypoallergenic* product that is free of common allergens such as milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat, gluten, soybeans, corn, and yeast. It contains no artificial colors, flavors, or preservatives.

This choline supplement is trusted by healthcare practitioners since 1969, and it's developed closely with physicians to ensure optimal outcomes for even the most sensitive individuals.

If you're looking for a choline supplement that supports your memory, attention, and focus, then Klaire Labs CDP Choline 250mg is a great option. It supplies the bioavailable, active form of choline, and citicoline is among the best-studied agents for supporting memory function and healthy cognition. This brain supportive nutrient is a precursor of phosphatidylcholine, glycerophosphatidylcholine, and acetylcholine, making it a great choice for those looking to optimize their brain health.

However, Klaire Labs CDP Choline 250mg may be a bit pricey for some people, and you may need to take more than one capsule a day if you're taking this for medical reasons. Some people may experience mild side effects, such as headaches or nausea, but overall, this is a great option for those looking to support their brain health.

Pros

  • Supplies the bioavailable, active form of choline.
  • Citicoline is among the best-studied agents for supporting memory function and healthy cognition.*
  • This brain supportive nutrient is a precursor of phosphatidylcholine, glycerophosphatidylcholine, and acetylcholine.

Cons

  • It may be a bit pricey for some people.
  • You may need to take more than one capsule a day if you're taking this for medical reasons.
  • Some people may experience mild side effects, such as headaches or nausea.

Buying Guide

When looking for the best choline supplement, there are a few key factors to consider. Here are some features to look for:

1. Type of Choline

There are several types of choline supplements available, including choline bitartrate, citicoline, and alpha-GPC. Each type has its own benefits and drawbacks, so it's important to choose the one that best fits your needs.

Choline bitartrate is the most common form of choline supplement and is often the most affordable. Citicoline is a more expensive option, but it may offer additional benefits for brain health. Alpha-GPC is another popular form of choline supplement that may have cognitive benefits.

2. Dosage

The recommended dosage of choline supplements varies depending on the type of choline and the individual's needs. It's important to choose a supplement that provides an appropriate dosage for your specific needs.

3. Form

Choline supplements are available in various forms, including capsules, powders, and liquids. Capsules are the most convenient option for most people, while powders and liquids may be more suitable for those who have difficulty swallowing pills.

4. Quality

When choosing a choline supplement, it's important to select a high-quality product from a reputable manufacturer. Look for supplements that are made with pure, high-quality ingredients and are free from contaminants.

5. Additional Ingredients

Some choline supplements may contain additional ingredients, such as vitamins, minerals, or other nutrients. While these ingredients may provide additional benefits, it's important to choose a supplement that contains only the ingredients you need and that is free from unnecessary additives.

By considering these factors, you can choose the best choline supplement to meet your needs and support your overall health.

Frequently Asked Questions

1. What is the best form of choline to take?

The best form of choline to take is dependent on individual needs and preferences. However, some of the most popular forms of choline supplements include Alpha-GPC, CDP-choline, and choline bitartrate. These forms of choline are highly bioavailable and can easily cross the blood-brain barrier.

2. What supplement is best for choline?

Alpha-GPC and CDP-choline are considered to be the best supplements for choline. These supplements are highly bioavailable and can easily cross the blood-brain barrier. Additionally, they have been shown to support cognitive function and memory.

3. Is it good to supplement with choline?

Choline is an essential nutrient that is required for many bodily functions, including liver function, brain development, and nerve function. While some individuals may be able to obtain sufficient choline through their diet, others may require supplementation to meet their daily needs.

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