Symptoms A-Z

Severe Thigh Pain Symptoms, Causes & Common Questions

Understand severe thigh pain symptoms, including 10 causes & common questions.

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10 Possible Severe Thigh Pain Causes

The list below shows results from the use of our quiz by Buoy users who experienced severe thigh pain. This list does not constitute medical advice and may not accurately represent what you have.

Femoral stress fracture

Femoral stress fracture means there is a break in the femur, or thighbone. The femur is the largest and strongest bone in the body and is important for bearing weight. A femoral stress fracture usually occurs in the top of the bone where it connects to the pelvis.

Stress fractures happen from overuse and/or from weakness in the bone from disease, rather than from trauma. Those in heavy physical training, such as athletes and military trainees, are vulnerable to femoral stress fracture. But anyone suffering from malnutrition or osteoporosis is vulnerable to a stress fracture, even with ordinary activities of daily living.

Symptoms include pain deep in the thigh or groin, especially during exercise. The pain may have started gradually instead of being sudden, as with a traumatic injury. The condition might be thought to be a simple strain.

Diagnosis is made through physical examination, with simple tests such as hopping on the painful leg, and imaging.

Treatment involves rest; improved nutrition; study of proper training and striding techniques; and sometimes surgery.

Rarity: Common

Top Symptoms: dull, achy hip pain, pain in one thigh, thigh pain, spontaneous hip pain

Urgency: Primary care doctor

Deep vein thrombosis

Deep vein thrombosis (DVT) is a blood clot that forms in a vein deep in the body. Most deep vein clots occur in the lower leg or thigh.

Rarity: Uncommon

Top Symptoms: fever, thigh pain, upper leg swelling, calf pain, butt pain

Urgency: Hospital emergency room

Thigh nerve issue (meralgia paresthetica)

Meralgia paresthetica is a nerve condition that causes an area of skin over the upper outer thigh to feel numb, tingly, or painful. This is caused by compression of a nerve known as the lateral cutaneous nerve of the thigh as it passes underneath a tough fibrous ligament known as the inguinal ligament.

Rarity: Rare

Top Symptoms: pain in the outside of the hip, pain in one thigh, thigh numbness, tingling upper leg, hip numbness

Symptoms that never occur with thigh nerve issue (meralgia paresthetica): new headache, swollen hip, swollen hips, swelling of one hip, leg swelling, weakness of both legs, leg weakness

Urgency: Primary care doctor

Thigh bruise

A bruise is the damage of the blood vessels that return blood to the heart (the capillaries and veins), which causes pooling of the blood. This explains the blue/purple color of most bruises.

Rarity: Rare

Top Symptoms: pain in one thigh, thigh pain from an injury, upper leg injury, thigh bruise, swelling of one thigh

Symptoms that always occur with thigh bruise: upper leg injury, thigh pain from an injury

Urgency: Self-treatment

Cellulitis

Cellulitis is a bacterial infection of the deep layers of the skin. It can appear anywhere on the body but is most common on the feet, lower legs, and face.

The condition can develop if Staphylococcus bacteria enter broken skin through a cut, scrape, or existing skin infection such as impetigo or eczema.

Most susceptible are those with a weakened immune system, as from corticosteroids or chemotherapy, or with impaired circulation from diabetes or any vascular disease.

Symptoms arise somewhat gradually and include sore, reddened skin.

If not treated, the infection can become severe, form pus, and destroy the tissue around it. In rare cases, the infection can cause blood poisoning or meningitis.

Symptom of severe pain, fever, cold sweats, and fast heartbeat should be seen immediately by a medical provider.

Diagnosis is made through physical examination.

Treatment consists of antibiotics, keeping the wound clean, and sometimes surgery to remove any dead tissue. Cellulitis often recurs, so it is important to treat any underlying conditions and improve the immune system with rest and good nutrition.

Rarity: Uncommon

Top Symptoms: fever, chills, facial redness, swollen face, face pain

Symptoms that always occur with cellulitis: facial redness, area of skin redness

Urgency: Primary care doctor

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Greater trochanteric pain syndrome

Greater trochanteric pain syndrome, also called trochanteric bursitis or GTPS, is an inflammation of the bursa of the greater trochanter. Bursae are the small "cushions" between tendons, bones, and muscles. The greater trochanter is th...

Peripheral arterial disease (pad)

Peripheral artery disease is also called PAD, intermittent claudication, or vascular disease. The large main artery from the heart is the aorta, and its smaller branches are the peripheral arteries.

In PAD these peripheral arteries are blocked with plaque, which is debris that builds up in the lining of these arteries and eventually cuts off the blood flow.

Risk factors for PAD include smoking, high blood pressure, and diabetes.

PAD usually involves arteries that lead to the legs, but can affect any artery. Symptoms include numbness and pain in the legs, especially with exercise when more circulation is needed but the flow is blocked.

It is important to seek treatment for these symptoms. PAD can lead to increased risk of heart attack, stroke, and infection as well as to gangrene, a life-threatening medical emergency.

Diagnosis is made through patient history, physical examination, blood tests, and sometimes a treadmill test, MRI, and arteriogram.

Treatment involves medication and surgery to open or bypass blocked arteries, and lifestyle changes regarding diet, exercise, and smoking cessation.

Rarity: Common

Top Symptoms: leg numbness, spontaneous foot pain, decreased exercise tolerance, cold feet, thigh pain

Symptoms that never occur with peripheral arterial disease (pad): calf pain from an injury, thigh pain from an injury

Urgency: Primary care doctor

Thigh bone infection (osteomyelitis)

Osteomyelitis of the thigh is a bacterial or fungal infection of the thigh bone, typically caused by Staph Aureus (40-50% of the time). It is difficult to diagnose as the infection can come from a break in the skin at the area or anywhere else in the body that spreads by blood.

Rarity: Rare

Top Symptoms: moderate fever, constant upper leg pain, spontaneous thigh pain, painful surgical site, warm red upper leg swelling

Symptoms that always occur with thigh bone infection (osteomyelitis): spontaneous thigh pain, constant upper leg pain

Urgency: Hospital emergency room

Patellofemoral pain syndrome

Patellofemoral pain syndrome (PFPS) is also called runner's knee, jumper's knee, anterior knee pain, chondromalacia patella, and patellofemoral joint syndrome.

Overuse through training for sports is a common cause, especially if there is a misalignment in the knee joint or a previous knee injury. This wears away the cartilage beneath the kneecap and causes pain on exercising.

It is most common in females and in young adults who are active in sports, but can affect anyone.

Symptoms include dull pain at the front of the knee and around the kneecap (patella) while running, squatting, or climbing stairs, or after prolonged sitting with knees bent.

Diagnosis is made through physical examination and through x-rays, CT scan, and/or MRI.

Treatment most often involves rest; over-the-counter pain relievers; low-impact exercise such as swimming or bicycling; physical therapy to strengthen and stabilize the knee; and orthotics (shoe inserts) to help correct a misaligned stride.

Surgery is needed only for severe cases, and is done through arthroscopy to remove any fragments of damaged cartilage.

Rarity: Common

Top Symptoms: knee pain, pain in one knee, knee pain that gets worse when going up stairs, dull, achy knee pain, knee pain that gets worse when squatting

Symptoms that always occur with patellofemoral pain syndrome: knee pain

Urgency: Primary care doctor

Compartment syndrome

Acute compartment syndrome describes the damage done to certain muscle groups of the arms or legs after a traumatic injury.

All of the long muscles are bundled into sections – "compartments" – by the white sheets of strong, tough connective tissue called fascia. If something interferes with circulation so that blood flow is trapped within the compartment, pressure rises because the fascia cannot stretch. This causes serious damage to the muscles and other tissues within the compartment.

Acute compartment syndrome is caused by a broken bone; a crush injury; burns, due to scarred and tightened skin; and bandages or casts applied before an injury has stopped swelling.

Symptoms can rapidly intensify. They include severe pain and tightness in the muscle; tingling or burning sensation; and sometimes numbness and weakness.

Acute compartment syndrome is a medical emergency which can result in loss of the limb. Take the patient to the emergency room or call 9-1-1.

Diagnosis is made through patient history and physical examination.

Treatment involves hospitalization for emergency surgery and, in some cases, skin graft.

Rarity: Rare

Top Symptoms: arm numbness, hand numbness, foot numbness, pain in one leg, thigh numbness

Urgency: Hospital emergency room

Questions Your Doctor May Ask About Severe Thigh Pain

To diagnose this condition, your doctor would likely ask the following questions:

  • Do you run for exercise or sport?
  • What is your body mass?
  • Do your symptoms get worse when you exercise?
  • Have you ever had any surgeries?

The above questions are also covered by our A.I. Health Assistant.

If you've answered yes to one or more of these questions

Take a quiz to find out what might be causing your severe thigh pain

Severe Thigh Pain Symptom Checker Statistics

People who have experienced severe thigh pain have also experienced:

  • 17% Lower Back Pain
  • 4% Deep, Throbbing Hip Pain
  • 4% Hip Pain

People who have experienced severe thigh pain were most often matched with:

  • 46% Deep Vein Thrombosis
  • 30% Femoral Stress Fracture
  • 23% Thigh Nerve Issue (Meralgia Paresthetica)

People who have experienced severe thigh pain had symptoms persist for:

  • 32% Over a month
  • 26% Less than a week
  • 22% Less than a day

Source: Aggregated and anonymized results from visits to the Buoy AI health assistant (check it out by clicking on “Take Quiz”).

Severe Thigh Pain Symptom Checker

Take a quiz to find out what might be causing your severe thigh pain

Disclaimer: The article does not replace an evaluation by a physician. Information on this page is provided as an information resource only, and is not to be used or relied on for any diagnostic or treatment purposes.