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Numbness in One Thigh: 9 Causes

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Are you noticing numbness in your thigh? Numbness in the thigh ranges in severity and causes can be mechanical, metabolic, inflammatory, or iatrogenic. Thigh numbness is often felt on the outer thigh, though it sometimes reaches the knee, and is often accompanied by other symptoms, such as burning or tingling.

9 most common cause(s)

Copper Deficiency
Illustration of a person thinking with cross bandaids.
Transient Ischemic Attack
Illustration of various health care options.
Bulging disc
Spinal Stenosis
Sciatica
Illustration of a person thinking with cross bandaids.
Piriformis syndrome
Illustration of various health care options.
Groin nerve irritation
Illustration of various health care options.
Compartment syndrome
Illustration of a doctor beside a bedridden patient.
Thigh nerve issue (meralgia paresthetica)

Symptoms of numbness and tingling in thigh

Numbness in one thigh can be described as a loss of sensation or tingling in that area. It is reasonable to be concerned if you experience this symptom, especially if associated characteristics described below are persistent or intense. The cause can range in severity and will likely need to be evaluated by a medical provider for a definitive answer.

Common characteristics of numbness in one thigh

For example, symptoms you may also experience that accompany your thigh numbness can include:

  • Burning
  • Tingling
  • Pins and needles sensation
  • Sensitivity to touch
  • Pain

Symptoms that extend beyond the thigh

Sensation in the thigh is primarily controlled by the lateral femoral cutaneous nerve. Because of this nerve's specific location, symptoms are often experienced most significantly in the outer (lateral) part of the thigh. Branches of the lateral femoral cutaneous nerve also supply the anterior and posterior portion of the thigh; thus, symptoms can be felt in these areas as well, sometimes extending to the knee. See this photo here of the lateral femoral cutaneous nerve and its area of innervation.

It is important to follow-up with your healthcare provider if you are experiencing any of the above symptoms. Numbness in the thigh can signal an underlying condition that requires prompt treatment.

What causes numbness in your thigh?

Changes in sensation occur when there is injury or disruption to a sensory nerve. The lateral femoral cutaneous nerve is particularly susceptible to injury or disruption in the form of compression because of its anatomical course in the body. It begins near the abdomen at the psoas muscle, then crosses diagonally over a bone in the pelvis called the anterior superior iliac spine, and then passes under, over or sometimes parallel to a structure called the inguinal ligament in the groin before going to the thigh.

See a visual representation of the lateral femoral cutaneous nerve here.

When the lateral femoral cutaneous nerve is damaged or compressed, a condition called meralgia paresthetica and its associated symptoms of numbness, tingling and pain results. There are four main categories of injury to the nerve in the case of meralgia paresthetica: mechanical, metabolic, inflammatory and iatrogenic (i.e. relating to a condition caused by medical examination or treatment).

Mechanical causes

Mechanical causes relate to issues that increase pressure on the groin or path of the lateral femoral cutaneous nerve.

  • Entrapment: Due to its course, the lateral femoral cutaneous nerve is susceptible to entrapment between the pelvic bone and the inguinal ligament, especially if it runs underneath. Seemingly mild activities such as cycling or walking, especially for long periods, can result in compression of the nerve between these two points. Traumatic injuries to the pelvis can also result in similar compression as well as damage to the nerve.
  • Environmental: External factors such as tight clothing can result in meralgia paresthetica. Any outerwear such as belts, tight pants, and even corsets can cause enough pressure on the nerve and result in meralgia paresthetica.
  • Weight: Pregnancy or weight gain localized to the abdominal region can also cause increased pressure on the groin or path of the lateral cutaneous nerve.
  • Tumors: Very rarely, cancerous and noncancerous growths in the body can directly compress nerves in the upper thigh, including the lateral femoral cutaneous nerve.

Metabolic causes

There are many systemic, metabolic conditions that can result in damage to the lateral femoral cutaneous nerve. These conditions affect the way that the nerve sends and receives signals from the brain and spinal cord and disrupts proper sensory function, resulting in a condition known as neuropathy.

  • Systemic: Dysfunction in the systemic processes that your body uses day-to-day, for example, glucose and insulin dysregulation in diabetes, can damage the lateral femoral cutaneous nerve causing numbness in the thigh and other parts of the body.
  • Toxins: Toxins that cause injury to the nerves include heavy metals such as lead and substances such as alcohol. Too much exposure to either can cause nerve damage that leads to numbness.

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Inflammatory causes

Inflammatory causes of numbness in one thigh may be related to:

  • Autoimmune: Many inflammatory diseases that result in the body attacking itself can also affect the nerves and cause injury that results in numbness. Conditions such as multiple sclerosis and lupus are examples of such autoimmune diseases.
  • Infections: Bacterial infections such as Lyme disease and multiple viral infections such as shingles can cause inflammation and nerve injury that results in thigh numbness.

Iatrogenic causes

An iatrogenic cause refers to any condition that results from medical examination or treatment. Due to its superficial course, the lateral femoral cutaneous nerve can often be injured or compressed in surgeries involving the pelvic area or lower abdomen.

This list does not constitute medical advice and may not accurately represent what you have.

Thigh nerve issue (meralgia paresthetica)

Meralgia paresthetica is a nerve condition that causes an area of skin over the upper outer thigh to feel numb, tingly, or painful. This is caused by compression of a nerve known as the lateral cutaneous nerve of the thigh as it passes underneath a tough fibrous ligament known as the inguinal ligament.

You should visit your primary care physician to confirm the diagnosis and discuss treatment options. Generally, this condition is treated with rest, physical therapy, pain medication, and occasionally corticosteroid injections.

Rarity: Rare

Top Symptoms: pain in the outside of the hip, pain in one thigh, thigh numbness, tingling upper leg, hip numbness

Symptoms that never occur with thigh nerve issue (meralgia paresthetica): new headache, swollen hip, swollen hips, swelling of one hip, leg swelling, weakness of both legs, leg weakness

Urgency: Primary care doctor

Stroke or tia (transient ischemic attack)

Transient ischemic attack, or TIA, is sometimes called a "mini stroke" or a "warning stroke." Any stroke means that blood flow somewhere in the brain has been blocked by a clot.

Risk factors include smoking, obesity, and cardiovascular disease, though anyone can experience a TIA.

Symptoms are "transient," meaning they come and go within minutes because the clot dissolves or moves on its own. Stroke symptoms include weakness, numbness, and paralysis on one side of the face and/or body; slurred speech; abnormal vision; and sudden, severe headache.

A TIA does not cause permanent damage because it is over quickly. However, the patient must get treatment because a TIA is a warning that a more damaging stroke is likely to occur. Take the patient to the emergency room or call 9-1-1.

Diagnosis is made through patient history; physical examination; CT scan or MRI; and electrocardiogram.

Treatment includes anticoagulant medication to prevent further clots. Surgery to clear some of the arteries may also be recommended.

Rarity: Common

Top Symptoms: dizziness, leg numbness, arm numbness, new headache, stiff neck

Symptoms that never occur with stroke or tia (transient ischemic attack): bilateral weakness

Urgency: Emergency medical service

Spinal stenosis

The spine, or backbone, protects the spinal cord and allows people to stand and bend. Spinal stenosis causes narrowing in the spine. The narrowing puts pressure on nerves and the spinal cord and can cause pain.

Next steps including visiting a primary care physician. For this condition, a physician might suggest further investigation including imaging of the spine. Treatments may include medications, physical therapy, or braces. For severe cases, surgery is sometimes recommended.

Rarity: Common

Top Symptoms: lower back pain, back pain that shoots down the leg, back pain that shoots to the butt, difficulty walking, thigh pain

Urgency: Primary care doctor

Sciatica

Sciatica is a general term describing any shooting leg pain that begins at the spine and travels down the outside of the leg. It is also called pinched nerve, lumbar radiculopathy, sciatic neuralgia, sciatic neuritis, or sciatic neuropathy.

By far the most common cause is a herniated or "slipped" disc in the lower spine. This means some of the cushioning material inside the disc has been forced outward and is pressing on a nerve root. Spasms of the piriformis muscle around the sciatic nerve, as well as the narrowing of the spinal canal called spinal stenosis, can also cause sciatica.

Symptoms include shooting leg pain that begins suddenly or develops gradually. There may be weakness, numbness, and a pins-and-needles sensation. In severe cases, there may be difficulty moving the foot or bending the knee.

Diagnosis is made through patient history, physical examination, and simple leg-raise tests.

Treatment involves physical therapy, nonsteroidal anti-inflammatory drugs, and muscle relaxants. In some cases, corticosteroid spinal injections and surgery may be tried. Massage and acupuncture are also sometimes helpful.

Piriformis syndrome

Piriformis syndrome

The two piriformis muscles, left and right, each run from the base of the pelvis to the top of the thighbone. The two sciatic nerves, left and right, are each attached to the spine and run down between the pelvic bone and the piriformis muscle to the back of each leg.

If the piriformis muscle is damaged through sudden trauma, or through overuse as in sports, the resulting inflammation or spasm of the muscle can trap the sciatic nerve between the pelvic bone and the muscle.

Piriformis syndrome is most often found in women over 30.

Symptoms include pain over one or both sides of the low back, and shooting pain (sciatica) down one or both legs.

Diagnosis is made through physical examination and sometimes imaging such as CT scan or MRI.

Treatment involves rest; over-the-counter, nonsteroidal anti-inflammatory drugs; physical therapy; therapeutic injections; and, rarely, surgery.

The best prevention is a good regimen of stretching before exercise, to help prevent damage to the piriformis.

Rarity: Common

Top Symptoms: pelvis pain, butt pain, pain when passing stools, leg numbness, hip pain

Symptoms that never occur with piriformis syndrome: involuntary defecation, leaking urine

Urgency: Primary care doctor

Herniated (slipped) disk in the lower back

A herniated, ruptured, or "slipped" disc means that a vertebral disc – one of the soft pads of tissue that sit between each of the vertebral bones – has becomes squeezed out of shape. Its cushioning material has been forced against, and possibly through, the ring of fibrous tissue that normally contains it. This causes pain, numbness, and weakness in the legs.

The normal aging process causes the discs lose moisture and become thinner, making them more vulnerable to "slipping."

Most susceptible are men from ages 30 to 50. Smoking, obesity, lack of exercise, and improper lifting are also risk factors.

Symptoms include pain, weakness, numbness, and tingling in the back, leg, and foot.

Diagnosis is made through patient history, neurological examination, and MRI scan.

Treatment begins with rest, nonsteroidal anti-inflammatory drugs, physical therapy, and sometimes epidural steroid injections into the back to ease pain and inflammation.

Surgery to remove the herniated part of the disc – the part that was squeezed out of place – can also be helpful.

Rarity: Common

Top Symptoms: lower back pain, moderate back pain, back pain that shoots down the leg, back pain that gets worse when sitting, leg weakness

Urgency: Primary care doctor

Groin nerve irritation

There are several nerves supplying the groin, inner thigh and genital region. Entrapment or irritation of one of these nerves can result in pain or numbness in this area. This is often caused by surgery in this area but can happen without a specific cause as well.

You should discuss your symptoms with your primary care physician. Sometimes a referral to a specialist is needed. Treatment often includes an injection with a local anesthetic.

Rarity: Rare

Top Symptoms: thigh numbness, groin numbness, testicle numbness, sharp testicle or scrotum pain, sharp groin pain

Urgency: Primary care doctor

Copper deficiency

Copper is a natural element necessary to many of the body's daily processes. Although found in the body in small amounts, copper is crucial to the proper functioning of the nervous, musculoskeletal, and immune systems, as well as the creation of red blood cells. A copper deficiency, or an insufficient amount of copper, can be due to a poor diet or malabsorption or an inherited disorder.

If your copper deficiency is acquired, you may experience fatigue, paleness, frequent infections, neurologic deficits, and bone and cardiovascular issues. If you or your child's copper deficiency is inherited, you may observe distinct facial features and kinky hair, a failure to thrive, weak muscles, seizures, and hypopigmentation.

Acquired copper deficiency can usually be remedied by supplements and a proper diet. However, effects of inherited copper deficiency are often permanent.

You should visit your primary care physician to confirm the diagnosis and discuss copper supplements

Compartment syndrome

Acute compartment syndrome describes the damage done to certain muscle groups of the arms or legs after a traumatic injury.

All of the long muscles are bundled into sections – "compartments" – by the white sheets of strong, tough connective tissue called fascia. If something interferes with circulation so that blood flow is trapped within the compartment, pressure rises because the fascia cannot stretch. This causes serious damage to the muscles and other tissues within the compartment.

Acute compartment syndrome is caused by a broken bone; a crush injury; burns, due to scarred and tightened skin; and bandages or casts applied before an injury has stopped swelling.

Symptoms can rapidly intensify. They include severe pain and tightness in the muscle; tingling or burning sensation; and sometimes numbness and weakness.

Acute compartment syndrome is a medical emergency which can result in loss of the limb. Take the patient to the emergency room or call 9-1-1.

Diagnosis is made through patient history and physical examination.

Treatment involves hospitalization for emergency surgery and, in some cases, skin graft.

Rarity: Rare

Top Symptoms: arm numbness, hand numbness, foot numbness, pain in one leg, thigh numbness

Urgency: Hospital emergency room

At-home and professional treatments for a numb thigh

Numbness in one thigh can be alleviated or prevented with a few at-home measures. If you cannot find relief, you should consult your physician. They can make further recommendations for medical treatment.

At-home treatments and preventative measures for numbness in one thigh

You can prevent more temporary symptoms with the following lifestyle changes:

  • Restrictions or movements: Avoid repetitive motions or cramped positions that put unnecessary pressure on your lateral femoral cutaneous nerve.
  • Exposures: Avoid toxic exposures such as alcohol and check your home and work environment for substances such as lead.
  • Clothing: Avoid tight clothing and opt for looser, more relaxed clothing especially around the pelvic region.

For temporary relief, consider applying topical pain relievers that can help alleviate minor nerve irritation. Products containing ingredients like lidocaine can be effective.

When to see a doctor for numbness in one thigh

However, if you experience frequent, persistent episodes of numbness, visit your physician to find to get appropriate treatment. Depending on the cause, your physician may suggest the following treatments:

  • Anticonvulsants: Some anticonvulsant medications (used for seizures) can also be used to combat nerve pain and include medications such as gabapentin.
  • Corticosteroid injections: Injections can reduce inflammation and help relieve pain; however they include certain side effects such as joint infection and nerve damage that you need to discuss with your healthcare provider before beginning.
  • Surgery: If other treatments are ineffective and your symptoms continue to progress or worsen, your physician may recommend looking into surgical options to combat your symptoms.

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FAQs about numbness in one thigh

Will the numbness in the thigh affect my gait or walking?

The numbness in your thigh should not affect your gait or walking because the lateral femoral cutaneous nerve is a pure sensory nerve that only provides innervation related to sensation and feeling. It does not affect your ability to use the muscles in your leg. If you are experiencing problems with your gait, make an appointment with your healthcare provider promptly; this could signal a different underlying condition.

Why am I only feeling numbness in one thigh?

You are only feeling numbness in one thigh because the nerve in that thigh has been affected, whereas the nerve in the other thigh has not.

Is numbness in one thigh life-threatening?

Usually, numbness in one thigh is not life-threatening, especially if it is related to damage or compression of the lateral femoral cutaneous nerve. There are life- and/or limb-threatening conditions such as compartment syndrome a situation in which increased pressure within a confined space can lead to inadequate blood supply to an organ that can also present as numbness. Usually, these conditions are associated with severe trauma and symptoms such as paralysis, lack of pulse and changes in the color of the extremity.

Will the numbness spread from my thigh to other parts of my lower body?

If your symptoms are only due to compression or injury to the lateral cutaneous femoral nerve, your symptoms should remain localized to the thigh and spread to as low as the knee. If you have neuropathy in other nerves caused by other conditions, you may also experience numbness in the hands, feet or toes as well.

How long will the numbness last?

Decompression of the nerve usually results in very fast relief. Decompression can be attained by simply wearing more loose-fitting clothing and does not necessarily require surgery.

Questions your doctor may ask about numbness in one thigh

  • Lie down. Have someone hold onto your foot on the affected side and try to rotate the foot inward. Does this cause pain?
  • Do your symptoms improve with activity (moving around and such)?
  • Do your symptoms worsen when sitting?
  • What is your body mass?

Self-diagnose with our free Buoy Assistant if you answer yes on any of these questions.

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The stories shared below are not written by Buoy employees. Buoy does not endorse any of the information in these stories. Whenever you have questions or concerns about a medical condition, you should always contact your doctor or a healthcare provider.
Dr. Rothschild has been a faculty member at Brigham and Women’s Hospital where he is an Associate Professor of Medicine at Harvard Medical School. He currently practices as a hospitalist at Newton Wellesley Hospital. In 1978, Dr. Rothschild received his MD at the Medical College of Wisconsin and trained in internal medicine followed by a fellowship in critical care medicine. He also received an MP...
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References

  1. Meralgia paresthetica. Mayo Clinic. Published March 8, 2018. Mayo Clinic Link
  2. Erbay H. Meralgia paresthetica in differential diagnosis of low-back pain. The Clinical Journal of Pain. 2002;18(2):132-5. NCBI Link
  3. Cheatham SW, Kolber MJ, Salamh PA. Meralgia paresthetica: A review of the literature. International Journal of Sports Physical Therapy. 2013;8(6):883-893. NCBI Link
  4. Ruane JJ, Bring BV. Meralgia paresthetica - a common cause of thigh pain. Practical Pain Management. Updated August 6, 2014. PPM Link
  5. Stewart M, Ariyasinghe C, et al. Lateral femoral cutaneous nerve. Radiopaedia.org. Radiopaedia Link