What is psoriatic disease?
Psoriatic disease is a chronic disease driven by an overactive immune system that attacks the skin and the joints.
It causes itchy, red, scaly patches (plaques) to appear on the skin (called psoriasis). Psoriasis is the most common inflammatory skin disease, affecting about 4% of the population. About a third of all people with psoriasis develop an inflammatory arthritis that causes pain and swelling in the joints (called ).
Most common symptoms
Ask your doctor: What is the best treatment for me, which is safe and will improve the symptoms of skin psoriasis and arthritis? —Dr. Petros Efthimiou
Psoriasis tends to appear on skin on the outside of the elbows, front of the knees, or the scalp. Though it can appear on any part of the body, including large plaques covering the torso. The plaques may itch and burn for some people.
Psoriatic arthritis causes swelling, pain, and stiffness in the joints. It can affect the large joints (e.g., knees), the small joints of the hands and feet, and the spine.
Causes of psoriatic disease
Psoriatic disease is an autoimmune disease where the immune system attacks skin and joints. There is a genetic component to the disease. A person is more likely to get it if a first degree relative, such as a mother, father, or sibling, has psoriasis.
Changes in the microbiome (the type of bacteria that live in the gut) have also been associated with an increased risk. Environmental factors such as exposure to cold, UV radiation, pollution, and smoking may also play a role.
Psoriatic disease is associated with other conditions such as diabetes, obesity, and depression.
Trauma to the skin (such as scratching or picking on the scales) can worsen skin psoriasis (known as Koebner phenomenon).
Treatment of psoriatic disease
Treatments are now very effective, both in the skin and the joints, and can lead to long-lasting remission. It may mean a better sense of well-being and decrease or even eliminate the need to constantly apply creams and lotions to the skin plaques. —Dr. Efthimiou
If you only have psoriasis (skin symptoms), see a dermatologist. If you have joint symptoms (or both skin and joint symptoms) see a rheumatologist (a doctor specializing in autoimmune disease and arthritis).
Mild skin symptoms (like a rash) can be treated with topical (applied to the skin) ointments, lotions, creams, and gels. These contain corticosteroids or vitamin D. Phototherapy (light therapy), which is being exposed to ultraviolet A (UVA) in a controlled way, may also be recommended.
If you have severe psoriasis or psoriatic arthritis, you will need to take oral medication or have injections or infusions. There are a range of medications to try. A few options include biologics, immunosuppressants, and disease-modifying antirheumatic drugs (DMARDs).
You should continue to have follow-up visits with your doctor (dermatologist and/or rheumatologist). Talk to your doctor before stopping any medication, as it may lead to a rebound of the disease.
You can take the following steps to help prevent recurrences or flare-ups:
- Use moisturizer
- Avoid dry, cold weather
- Use a humidifier
- Stop smoking
- Eat healthy and exercise, avoid excess alcohol
- Avoid scrapes, bumps, and tattoos
- Ask your doctor about substitutes for medication you’re taking that can make psoriasis worse (beta blockers, lithium, hydroxychloroquine, quinidine)
- Avoid or reduce stress